Dithioles
Chem-Impex International, Inc. 4-Propylbenzoic acid | 2438-05-3 | MFCD00013996 | 25G
4-Propylbenzoic acid, 2438-05-3, MFCD00013996, 25G
Cayman Chemical 2H 2H 3H 3HPerfluorohexnoIc 1g
A polyfluoroalkyl substance; has been found as a contaminant in sea and river water
Medchemexpress LLC Malotilate | 59937-28-9 | C12H16O4S2 | 50 MG
Malotilate is an orally active hepatotropic agent and an anti-fibrotic substance. It selectively inhibits 5-lipoxygenase (5-LOX) with an IC50 of 4.7 μM. It helps prevent the development of hepatocytic injury in alcohol-pyrazole hepatitis by reducing hepatic acetaldehyde levels and preventing the retention of transferrin in hepatocytes.
- Selectively inhibits 5-lipoxygenase (5-LOX) (IC50=4.7 μM).
- Prevents the development of hepatocytic injury in alcohol-pyrazole hepatitis by decreasing hepatic acetaldehyde levels.
- Prevents the retention of transferrin in the hepatocytes.
Apexbio Technology LLC Thiolutin(Synonyms: Acetopyrrothin, Farcinicin, Aureothricin, Antibiotic 810, Pyrrothine, Nocathiacin), 10mg, CAS: 32087.
Thiolutin (CAS 87-11-6) is a microbial-derived antibiotic known to inhibit RNA polymerase activity in bacteria It also interferes with the adhesion process of human umbilical vein endothelial cells (HUVECs) to vitronectin displaying an IC value of approximately 0 83 mM and subsequently reduces cellular paxillin expression Through these actions thiolutin effectively diminishes tumor cell-induced angiogenesis making it a useful tool compound in research exploring transcription regulation cell adhesion processes and tumor-related angiogenic mechanisms
Medchemexpress LLC Malotilate | 59937-28-9 | 99.5% | C12H16O4S2 | 100 MG
Malotilate is an orally active hepatotropic agent and an anti-fibrotic substance. It selectively inhibits 5-lipoxygenase (5-LOX) with an IC50 of 4.7 μM. It prevents the development of hepatocytic injury in alcohol-pyrazole hepatitis by decreasing hepatic acetaldehyde levels and preventing the retention of transferrin in the hepatocytes. For research use only.
- Reduces collagen synthesis and cell migration activity of fibroblasts in vitro
- Stimulates 12- and 15-lipoxygenase pathways
- Prevents acute experimental liver injury induced by various hepatotoxic compounds
- Normalizes lowered serum cholesterol in rats with hypocholesterolemia
- Normalizes inhibition of triglyceride secretion from livers in rats with CCl4-induced liver damage
Chem-Impex International, Inc. 3H-1,2-Benzodithiol-3-one-1,1-dioxide | 66304-01-6 | MFCD00132960 | 25G
3H-1,2-Benzodithiol-3-one-1,1-dioxide, 66304-01-6, MFCD00132960, 25G
Accela Chembio Inc Tetrathiafulvalene | 5g | 31366-25-3 | MFCD00005492 | 97+% | Shelf Life: 540 Days | Light Sensitive/nitrogen Or Argon/+4
Tetrathiafulvalene | 5g | 31366-25-3 | MFCD00005492 | 97+% | Shelf Life: 540 Days | Light Sensitive/nitrogen Or Argon/+4
Medchemexpress LLC Thiolutin (Acetopyrrothin) | 87-11-6 | 5 MG
Thiolutin (Acetopyrrothin) | 87-11-6 | 5 MG
Medchemexpress LLC Thiolutin (Acetopyrrothin) | 87-11-6 | 10 MG
Thiolutin (Acetopyrrothin) is a sulfur-containing antibiotic and a potent inhibitor of bacterial and yeast RNA polymerases. Produced by Streptomyces, it functions as a dual inhibitor of BRCC36 and the NLRP3 inflammasome, demonstrating anti-inflammatory and anti-angiogenic properties.
- Sulfur-containing antibiotic
- Potent inhibitor of bacterial and yeast RNA polymerases
- Inhibits AMSH and Rpn11
- Dual inhibitor of BRCC36 and the NLRP3 inflammasome
- Anti-inflammatory effects
- Inhibits HCC growth by suppressing BRCC36 and HMGCR interaction
- Attenuates pyroptosis and NLRP3 inflammasome activation
- Alleviates renal injury and inflammatory processes in IgAN
- Acts as an anti-angiogenic compound
- Eases Doxorubicin-induced cardiotoxicity
Medchemexpress LLC Thiolutin (acetopyrrothin) | 87-11-6 | 1 ML
Thiolutin (Acetopyrrothin) is a sulfur-containing antibiotic and a potent inhibitor of bacterial and yeast RNA polymerases. It is produced by Streptomyces. Thiolutin inhibits AMSH (IC50 = 4 μM) and Rpn11 (IC50 = 0.53 μM). It acts as a dual inhibitor of BRCC36 and the NLRP3 inflammasome, demonstrating anti-inflammatory effects and effectively suppressing the interaction between BRCC36 and HMGCR, thereby inhibiting HCC growth.
- Potent inhibitor of bacterial and yeast RNA polymerases.
- Inhibits AMSH (IC50 = 4 μM) and Rpn11 (IC50 = 0.53 μM).
- Dual inhibitor of BRCC36 and the NLRP3 inflammasome, exhibiting anti-inflammatory effects.
- Suppresses the interaction between BRCC36 and HMGCR, inhibiting HCC growth.
- Attenuates pyroptosis and NLRP3 inflammasome activation.
- Alleviates renal injury and inflammatory process in IgAN.
- Anti-angiogenic compound that can ease doxorubicin-induced cardiotoxicity (DOXIC).
Tetrathiafulvalene-d4, TCI America™
CAS: 51751-16-7 Molecular Formula: C6H4S4 Molecular Weight (g/mol): 208.362 MDL Number: MFCD00191580 InChI Key: FHCPAXDKURNIOZ-RHQRLBAQSA-N Synonym: TTF-d4 PubChem CID: 12207880 IUPAC Name: 4,5-dideuterio-2-(4,5-dideuterio-1,3-dithiol-2-ylidene)-1,3-dithiole SMILES: C1=CSC(=C2SC=CS2)S1
4,5-Methylenedithio-1,3-dithiol-2-one 95.0+%, TCI America™
CAS: 85720-62-3 Molecular Formula: C4H2OS4 Molecular Weight (g/mol): 194.299 MDL Number: MFCD00137885 InChI Key: VBZVKFOMXXSGFB-UHFFFAOYSA-N PubChem CID: 2060090 IUPAC Name: [1,3]dithiolo[4,5-d][1,3]dithiol-5-one SMILES: C1SC2=C(S1)SC(=O)S2