Imidazopyrimidines
![Research Products International Corp Adenine [6-Aminopurine] [Vitamin B4] USP, 1 KG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/VN00006095-A11500-1000.0.JPG-250.jpg)
Research Products International Corp Adenine [6-Aminopurine] [Vitamin B4] USP, 1 KG
A nucleobase with a variety of roles in biochemistry including cellular respiration, in the form of both the energy-rich adenosine triphosphate and the cofactors nicotinamide adenine dicucleotide and flavin adenine dinucleotide, and protein synthesis, as a chemical component of DNA and RNA.
Medchemexpress LLC Adenine | 73-24-5 | 99.99% | 1 G
Adenine (6-Aminopurine) is a purine and one of the four nucleobases found in DNA. It functions as a chemical component of both DNA and RNA, playing a vital role in biochemistry, particularly in cellular respiration where it forms part of ATP and cofactors like NAD and FAD, and in protein synthesis.
- Chemical component of DNA and RNA
- Important in cellular respiration, forming ATP, NAD, and FAD
- Involved in protein synthesis
- Purity of 99.99%
- Molecular weight of 135.13
- Formula C5H5N5
- White to off-white solid appearance
- Soluble in DMSO (≥ 10 mg/mL) and H2O (2 mg/mL with warming)
- Utilized to induce chronic kidney injury models
- Used in inducing Chronic Kidney Disease (CKD) models in mice and rats
Medchemexpress LLC Adenine (Standard) | 73-24-5 | 99.9% | 100 MG
Adenine (Standard) is the analytical standard of Adenine, intended for research and analytical applications. Adenine (6-Aminopurine), a purine, is one of the four nucleobases in the nucleic acid of DNA. It acts as a chemical component of DNA and RNA and plays an important role in biochemistry involved in cellular respiration, the form of both ATP and the cofactors (NAD and FAD), and protein synthesis. The compound is an analytical standard, supplied as a reference standard assay.
- Commonly used in qualitative, quantitative, and methodological research experiments
- Suitable for HPLC, GC, and MS applications
Medchemexpress LLC FAPy-adenine | 5122-36-1 | 99.9% | 153.14 | 50 MG
FAPy-adenine is an oxidized DNA base. Increased levels of FAPy-adenine have been observed in the brains of individuals with Alzheimer's disease.
- Oxidized nucleosides are biochemical markers for various conditions, including tumors, aging, and neurodegenerative diseases.
- Intended for research use only and not for patient use.
Medchemexpress LLC Adenine phosphate | 70700-30-0 | 100.0% | 233.12 | 5 G
Adenine phosphate (6-Aminopurine phosphate) can stimulate leukocyte proliferation. It is a biological material or organic compound widely used in life science research.
- Appears as a solid
- Color is white to off-white
- Can be stored at room temperature, dry and cool
- Soluble in DMSO (11.67 mg/mL)
Sigma Aldrich Fine Chemicals Biosciences Adenine 99100G
Adenine is a purine nucleobase. It is part of DNA and RNA. Adenine is also a component of cofactors (NAD fAD) and signaling molecules (cAMP).
Medchemexpress LLC Xanthine oxidase, Microorganism | 9002-17-9 | ≥10 U/mg solid | 283 kDa | 100 U
Xanthine oxidase, Microorganism (XO) is a xanthine oxidoreductase enzyme that generates reactive oxygen species (ROS). It catalyzes the oxidation of hypoxanthine to xanthine, and further catalyzes the oxidation of xanthine to uric acid. This product is for research use only.
- Generates reactive oxygen species (ROS)
- Catalyzes oxidation of hypoxanthine to xanthine
- Catalyzes oxidation of xanthine to uric acid
- Rapidly and completely depletes hypoxanthine in human erythrocytes
- Inhibits growth of Plasmodium falciparum in human erythrocytes in vitro
- Reduces viability of postnatal cerebellar granule neurons
- Optimal pH is 7.5-8.0
- Soluble in water at 10 mg/mL or higher
Sigma Aldrich Fine Chemicals Biosciences 1-Methylxanthine-2,4,5,6-13C4, 1,3,9-15N3 >=98 atom %, >=98% (CP) | 1173018-69-3 | 5MG
1-Methylxanthine-2,4,5,6-13C4, 1,3,9-15N3 >=98 atom %, >=98% (CP) | Purity: >=98% (CP) | Mol Wt: 173.09 | 1173018-69-3 | 5MG
Medchemexpress LLC Theobromine | 83-67-0 | >99.55% | 180.17 | 1 ML
Theobromine is a methylxanthine found in cacao beans that can inhibit adenosine receptor A1 (AR1) signaling. It is intended for research use only.
- Inhibits adenosine receptor A1 (AR1) signaling
- Decreases lipid accumulation at concentrations above 25 μM without affecting cell viability
- Suppresses protein expression of PPARγ, C/EBPα, and adipogenic genes at concentrations above 25 μM
- Lowers body weight and suppresses gains in epididymal and perirenal adipose tissues in vivo
- Reduces mean adipocyte area in vivo
- Leads to lower bacterial counts per fecal weight in vivo
- Increases fecal pH values in vivo
Medchemexpress LLC 3-isobutyl-1-methylxanthine | 28822-58-4 | MFCD00005584 | >98.0% | 222.24 g/mol | C10H14N4O2 | 1G
IBMX (3-isobutyl-1-methylxanthine) is a non-selective cyclic nucleotide phosphodiesterase inhibitor used in research to raise intracellular cAMP and cGMP and to probe PKA/PKG signaling pathways. Supplied as a solid research reagent, it is used in biochemical assays and cell-based studies to pharmacologically increase cyclic nucleotide levels.
- Non-selective phosphodiesterase inhibitor that elevates cAMP and cGMP.
- Commonly used in cell signaling and biochemical assay workflows.
- Purity >98.0% by HPLC (typical specification).
- Chemical formula C10H14N4O2; molecular weight 222.24 g/mol.
- CAS number 28822-58-4 for unambiguous identification.
- Available in small-scale research pack sizes as a solid powder.
Chem-Impex International, Inc. Xanthine | 69-89-6 | MFCD00078453 | 5G
Xanthine, 69-89-6, MFCD00078453, 5G
eMolecules Chem-Impex Caffeine 10kg 490848238 33898 0 000 58-08-2 MFCD00005758 194 194 C8H10N4O2
Chem-Impex Caffeine 10kg 490848238 33898 0 000 58-08-2 MFCD00005758 194 194 C8H10N4O2
Medchemexpress LLC 3-isobutyl-1-methylxanthine | 28822-58-4 | MFCD00005584 | 100.0% | 222.24 g/mol | C10H14N4O2 | 5G
IBMX (3-isobutyl-1-methylxanthine) is a broad-spectrum phosphodiesterase (PDE) inhibitor used in research to raise intracellular cyclic AMP and probe signaling pathways. It is provided as a solid reagent for biochemical and cell-based assays.
- Broad-spectrum phosphodiesterase inhibitor.
- Inhibitory activity: PDE3 IC50 6.5 μM, PDE4 IC50 26.3 μM, PDE5 IC50 31.7 μM.
- Molecular formula C10H14N4O2; molecular weight 222.24 g/mol.
- Supplied as a powdered reagent suitable for research use.
- Storage: powder -20°C for long-term storage, 4°C for shorter storage.
- Reported purity approximately 99.97% by HPLC.
- Used to elevate intracellular cAMP in biochemical and cell signaling studies.
Medchemexpress LLC (R)-lisofylline | 100324-81-0 | MFCD00867573 | 100.0% | 280.32 g/mol | C13H20N4O3 | 5 MG
(R)-Lisofylline is the R-enantiomer of lisofylline, a metabolite of pentoxifylline with documented anti-inflammatory activity. It is used as a research compound to probe lipid signaling and immune pathways, including inhibition of lysophosphatidic acid acyltransferase and disruption of IL-12-mediated STAT4 activation.
- R-enantiomer of lisofylline.
- Lysophosphatidic acid acyltransferase inhibitor (reported IC50 ≈ 0.6 μM).
- Modulates IL-12-STAT4 signaling relevant to immunology research.
- Provided in small milligram research packs for laboratory use.
- Store under nitrogen at -20°C; in solvent, -80°C for up to 6 months.
- Molecular weight 280.32 g/mol; formula C13H20N4O3.
Sigma Aldrich Fine Chemicals Biosciences 3-Isobutyl-1-methylxanthine BioUltra, 99, 28822-58-4, MFCD00005584
3-Isobutyl-1-methylxanthine BioUltra, 99