Imidazopyrimidines
Medchemexpress LLC 3-isobutyl-1-methylxanthine | 28822-58-4 | MFCD00005584 | 100.0% | 222.24 g/mol | C10H14N4O2 | 5G
IBMX (3-isobutyl-1-methylxanthine) is a broad-spectrum phosphodiesterase (PDE) inhibitor used in research to raise intracellular cyclic AMP and probe signaling pathways. It is provided as a solid reagent for biochemical and cell-based assays.
- Broad-spectrum phosphodiesterase inhibitor.
- Inhibitory activity: PDE3 IC50 6.5 μM, PDE4 IC50 26.3 μM, PDE5 IC50 31.7 μM.
- Molecular formula C10H14N4O2; molecular weight 222.24 g/mol.
- Supplied as a powdered reagent suitable for research use.
- Storage: powder -20°C for long-term storage, 4°C for shorter storage.
- Reported purity approximately 99.97% by HPLC.
- Used to elevate intracellular cAMP in biochemical and cell signaling studies.
Medchemexpress LLC (R)-Lisofylline | 100324-81-0 | 99.99% | 280.32 | 500 MG
(R)-Lisofylline | 100324-81-0 | 99.99% | 280.32 | 500 MG
eMolecules 58-08-2 | Caffeine | Chem-Impex | MFCD00005758 | 194.194 | C8H10N4O2 | 99.000 | Cn1cnc2n(C)c(=O)n(C)c(=O)c12 | 1kg | 490848235
Caffeine | Chem-Impex | 58-08-2 | MFCD00005758 | 194.194 | C8H10N4O2 | 99.000 | Cn1cnc2n(C)c(=O)n(C)c(=O)c12 | 1kg | 490848235
Medchemexpress LLC Xanthine oxidase, bovine milk | 9002-17-9 | 283 kDa | 5 U
Xanthine oxidase, bovine milk is an oxidoreductase enzyme that generates reactive oxygen species (ROS). It catalyzes the oxidation of hypoxanthine to xanthine, and further catalyzes the oxidation of xanthine to uric acid. This product is for research use only.
- Generates reactive oxygen species
- Catalyzes oxidation of hypoxanthine to xanthine
- Catalyzes oxidation of xanthine to uric acid
- Depletes hypoxanthine in human erythrocytes
- Inhibits growth of Plasmodium falciparum in human erythrocytes
- Reduces viability of postnatal cerebellar granule neurons
Medchemexpress LLC Xanthine | 69-89-6 | MFCD00078453 | 99.1% | 152.11 g/mol | C5H4N4O2 | 100 G
Xanthine (CAS 69-89-6) is a purine base and endogenous metabolite involved in purine degradation. It is used as a research reagent and reference standard in biochemical and analytical workflows, including metabolic pathway studies and instrument calibration.
- Used as a research reagent and reference standard for analytical assays.
- Reference-standard grades available with documented purity for quantitative work.
- Well-characterized molecular identity: C5H4N4O2, MW 152.11 g/mol.
- Suitable for use in chromatography and mass spectrometry calibration.
- Applicable to studies of purine metabolism and enzymatic pathways.
Medchemexpress LLC 3-isobutyl-1-methylxanthine | 28822-58-4 | MFCD00005584 | >98.0% | 222.24 g/mol | C10H14N4O2 | 1G
IBMX (3-isobutyl-1-methylxanthine) is a non-selective cyclic nucleotide phosphodiesterase inhibitor used in research to raise intracellular cAMP and cGMP and to probe PKA/PKG signaling pathways. Supplied as a solid research reagent, it is used in biochemical assays and cell-based studies to pharmacologically increase cyclic nucleotide levels.
- Non-selective phosphodiesterase inhibitor that elevates cAMP and cGMP.
- Commonly used in cell signaling and biochemical assay workflows.
- Purity >98.0% by HPLC (typical specification).
- Chemical formula C10H14N4O2; molecular weight 222.24 g/mol.
- CAS number 28822-58-4 for unambiguous identification.
- Available in small-scale research pack sizes as a solid powder.
Medchemexpress LLC Theobromine | 83-67-0 | >99.55% | 180.17 | 1 ML
Theobromine is a methylxanthine found in cacao beans that can inhibit adenosine receptor A1 (AR1) signaling. It is intended for research use only.
- Inhibits adenosine receptor A1 (AR1) signaling
- Decreases lipid accumulation at concentrations above 25 μM without affecting cell viability
- Suppresses protein expression of PPARγ, C/EBPα, and adipogenic genes at concentrations above 25 μM
- Lowers body weight and suppresses gains in epididymal and perirenal adipose tissues in vivo
- Reduces mean adipocyte area in vivo
- Leads to lower bacterial counts per fecal weight in vivo
- Increases fecal pH values in vivo
Medchemexpress LLC 3-Methylxanthine | 1076-22-8 | 99.5% | C6H6N4O2 | 1 ML
3-Methylxanthine is a xanthine derivative and a cyclic guanosine monophosphate (GMP) inhibitor, with an IC50 of 920 μM on guinea-pig isolated trachealis muscle. This product is provided as a solid with a purity of 99.45%.
- Xanthine derivative
- Cyclic guanosine monophosphate (GMP) inhibitor
- IC50 of 920 μM on guinea-pig isolated trachealis muscle
- Provided as a solid
- Purity of 99.45% (HPLC)
- Stable under recommended storage conditions