Imidolactams
Apexbio Technology LLC Cell-permeable Src family tyrosine kinase inhibitor 172889-26-8. MFCD01076570
Cell-permeable Src family tyrosine kinase inhibitor 172889-26-8. MFCD01076570
Medchemexpress LLC DHC-156 | 99.5% | 492.47 g·mol⁻¹ | C24H24F4N4O3 | 10 MG
DHC-156 is a selective small-molecule downmodulator of the transcription factor Brachyury, developed for preclinical research into chordoma. It downmodulates brachyury post-translationally and has been shown to impair chordoma cell growth. Intended for research use only.
- Selective downmodulator of the transcription factor Brachyury.
- Downmodulates brachyury post-translationally and impairs chordoma cell growth.
- Chemical formula: C24H24F4N4O3.
- Molecular weight: 492.47 g·mol⁻¹.
- High purity (99.5%).
- Available in multiple pack sizes, including 10 mg.
- Supplied for research use only; not for human or clinical use.
Apexbio Technology LLC Pregnenolone Carbonitrile(Synonyms: PCN, Pregnenolone-16α-carbonitrile, Pregn-5-en-20-one-16α-carbonitrile), 50mg, CAS: 1434-54-4.
Pregnenolone Carbonitrile (CAS 1434-54-4) known as Pregnenolone-16 -carbonitrile (PCN) is a pregnane X receptor (PXR) agonist primarily utilized in biomedical research investigating xenobiotic metabolism pathways By activating rodent nuclear PXR PCN stimulates expression of cytochrome P450 enzymes notably of the CYP3A subfamily enhancing hepatic detoxification and clearance of diverse foreign substances Independently of PXR PCN exhibits antifibrotic activity in liver fibrosis models shown by inhibition of hepatic stellate cell trans-differentiation in vitro and decreased hepatic fibrosis in vivo PCN thus serves as a useful tool for studying both PXR-dependent gene regulatory mechanisms and PXR-independent anti-fibrogenic effects
Medchemexpress LLC (S,R,S)-AHPC-Me-PEG2-dabrafenib | 2769753-69-5 | 99.9% | 1106.31 g/mol | C53H62F3N9O8S3 | 5 MG
DD-03-156 ((S,R,S)-AHPC-Me-PEG2-dabrafenib) is a selective small-molecule degrader developed for research use that targets cyclin-dependent kinase 17 (CDK17) and LIM kinase 2 (LIMK2). The compound is provided as a high-purity solid in milligram-scale quantities and is intended for biochemical and cell-based studies with recommended low-temperature storage under inert atmosphere.
- Selective degrader of CDK17 and LIMK2.
- High reported purity suitable for research assays.
- Supplied in milligram-scale quantities for exploratory studies.
- Stable under recommended low-temperature storage when handled under inert atmosphere.
- Includes molecular characterization and CAS registry number for traceability.