Lactams
Medchemexpress LLC Thalidomide-pinacolborane | 2229725-98-6 | 97.0% | 384.19 g/mol | C19H21BN2O6 | 250 MG
Thalidomide-pinacolborane is a thalidomide analogue that incorporates a boronic pinacol ester (Bpin). It is used as a synthetic intermediate for cross-coupling chemistry and as an E3 ligase (cereblon) ligand in chemical biology and targeted protein degradation research.
- Contains a boronic pinacol ester suitable for Suzuki-Miyaura cross-coupling.
- Functions as an E3 ligase (cereblon) ligand for PROTAC and degradation studies.
- High purity appropriate for research applications.
- Available in research-scale quantities for assay development.
- Molecular formula C19H21BN2O6; molecular weight 384.19 g/mol.
Medchemexpress LLC Thalidomide-NH-PEG1-NH2 hydrochloride | 2154342-56-8 | 99.2% | C17H21ClN4O5 | 10MG
Thalidomide-NH-PEG1-NH2 hydrochloride is a thalidomide-derived cereblon E3 ligase ligand-linker conjugate supplied as the hydrochloride salt and intended as a building block for PROTAC design and small-molecule degradation strategies. It couples a cereblon-recruiting moiety with a short PEG1 diamine linker to facilitate conjugation to target-binding ligands and streamline synthesis workflows.
- Provides thalidomide-based cereblon recruiting moiety.
- Includes a short PEG1 diamine linker for flexibility in conjugation.
- Supplied as hydrochloride salt for improved stability and handling.
- High purity suitable for synthetic applications (99.2%).
- Available in small milligram quantities for early-stage research.
![eMolecules Medchem Express / Thalidomide-Propargyne-PEG2-COOH / 50mg / 626717252 / HY-138777 / / 2797619-65-7 / [null] / 428.397 / C21H20N2O8](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502480460.JPG-250.jpg)
eMolecules Medchem Express / Thalidomide-Propargyne-PEG2-COOH / 50mg / 626717252 / HY-138777 / / 2797619-65-7 / [null] / 428.397 / C21H20N2O8
Medchem Express / Thalidomide-Propargyne-PEG2-COOH / 50mg / 626717252 / HY-138777 / / 2797619-65-7 / [null] / 428.397 / C21H20N2O8
eMolecules Thalidomide-Acid | 1061605-21-7 | | 1g
Broadpharm | Thalidomide-Acid | 1g | 550804650 | BP-24447 | 98.000 | 1061605-21-7 | | 332.268 | C15H12N2O7
If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link:
eMolecules Building Block Tool
Medchemexpress LLC Tetrazine-tagged thalidomide | 2087490-42-2 | 98.6% | 571.58 g/mol | C29H29N7O6 | 25 MG
Tz-Thalidomide is a tetrazine-tagged derivative of thalidomide designed as a chemical probe and building block for targeted protein degradation and molecular-glue research. Supplied as a research reagent for laboratory use only (not for human or clinical applications).
- Tetrazine-tagged thalidomide derivative for click chemistry (iEDDA).
- Suitable as a building block in PROTAC and molecular-glue studies.
- High purity, typically 98.6%.
- Available in small research pack sizes, including 25 mg.
- Molecular formula C29H29N7O6; molecular weight 571.58 g/mol.
Medchemexpress LLC Thalidomide-4-O-C6-NH2 hydrochloride | 2245697-88-3 | 98.5% | C19H24ClN3O5 | 10MG
Thalidomide-4-O-C6-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate used in PROTAC research, notably as a component of the degrader dTAG-13 that directs FKBP12F36V and BET proteins for degradation. It is intended for laboratory research into E3 ligase recruitment, targeted protein degradation, apoptosis, and autophagy.
- High purity suitable for research (98.5%).
- Soluble in DMSO at 83.33 mg/mL (203.31 mM); ultrasonic assistance may be needed.
- Engages cereblon for E3 ligase-mediated protein degradation.
- Useful for PROTAC assembly and linker conjugation workflows.
- Available in small research quantities to support assay development.
- Recommended storage: 4°C sealed, away from moisture and light; in solvent, store at -80°C for long term.
Medchemexpress LLC Thalidomide-NH-PEG3-COOH | 2375283-62-6 | 98.9% | 477.46 | C22H27N3O9 | 5 MG
Thalidomide-NH-PEG3-COOH is a synthesized E3 ligase ligand-linker conjugate that combines a thalidomide-derived cereblon ligand with a three-unit polyethylene glycol (PEG3) linker terminating in a carboxylic acid. It is intended as a modular building block for PROTAC development to recruit CRBN and enable linker attachment to target-binding ligands.
- Designed for PROTAC assembly and CRBN recruitment.
- Contains a PEG3 linker terminating in a carboxylic acid for facile conjugation.
- Incorporates a thalidomide-based cereblon ligand.
- High chemical purity (≈98.9%).
- Suitable for medicinal chemistry and chemical biology applications.
![eMolecules Pharmablock / tert-butyl N-(9-azabicyclo[3.3.1]nonan-3-yl)carbamate / 25mg / 721772855 / PBTEN0138 / 0.000 / 1208530-70-4 / MFCD13196387 / 240.347 / C13H24N2O2](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502451719.PNG-250.jpg)
eMolecules Pharmablock / tert-butyl N-(9-azabicyclo[3.3.1]nonan-3-yl)carbamate / 25mg / 721772855 / PBTEN0138 / 0.000 / 1208530-70-4 / MFCD13196387 / 240.347 / C13H24N2O2
Pharmablock / tert-butyl N-(9-azabicyclo[3.3.1]nonan-3-yl)carbamate / 25mg / 721772855 / PBTEN0138 / 0.000 / 1208530-70-4 / MFCD13196387 / 240.347 / C13H24N2O2
Cell Signaling Technology Phospho-IKK-epsilon (Ser172) (D1B7) Rabbit mAb 20 ul
Phospho-IKK-epsilon (Ser172) (D1B7) Rabbit mAb 20 ul
U.S. Pharmacopeia Sulbactam, 68373-14-8, MFCD00867005, 250mg
Molecular formula C8H11NO5S, Molecular weight 233.24, Melting Point 298.4 - 303.8 °F (148 - 151 °C) (also reported as 170 °C), Synonyms: Penicillanic acid 1,1-dioxide. Cold Shipment Required