Lactams
Medchemexpress LLC Sulbactam pivoxil | 69388-79-0 | MFCD00867003 | 98.0% | 347.38 g·mol⁻¹ | C14H21NO7S | 1 ML
Sulbactam pivoxil is the pivoxil prodrug of sulbactam, a β-lactamase inhibitor used in antibacterial research. It is supplied for research and analytical applications and is available as an analytical solid or as a ready-to-use 10 mM solution in DMSO.
- Available as solid and 10 mM solution in DMSO.
- Purity 98.0%.
- Molecular weight 347.38 g·mol⁻¹.
- Chemical formula C14H21NO7S.
- Recommended storage: powder -20°C for long term; in solvent -80°C for extended storage.
- Supplied with datasheet, certificate of analysis, and safety data sheet.
Medchemexpress LLC Sulbactam | 68373-14-8 | 100.0% | 1 ML
Sulbactam is a competitive, irreversible beta-lactamase inhibitor that demonstrates antimicrobial activity against multidrug-resistant (MDR) Acinetobacter calcoaceticus-Acinetobacter baumannii (Acb) complex. It exhibits a wide range of antibacterial activity against both Gram-positive and Gram-negative aerobic and anaerobic bacteria.
- Competitive, irreversible beta-lactamase inhibitor
- Antimicrobial against multidrug-resistant Acinetobacter calcoaceticus-Acinetobacter baumannii (Acb) complex
- Wide range of antibacterial activity
- Active against Gram-positive and Gram-negative aerobic and anaerobic bacteria
- For research use only
Medchemexpress LLC (R)-Thalidomide | 2614-06-4 | 99.8% | 258.23 | 1 MG
(R)-Thalidomide, also known as (R)-(+)-Thalidomide, is the R-enantiomer of Thalidomide, possessing psychomotor stabilizing properties. It is intended for research use only and is not sold to patients.
- (R)-Thalidomide binds more strongly to the selective sites of MIP (molecularly imprinted polymer) compared to other forms, indicating distinct biological entities.
- In vivo studies in F344 rats with 9L gliosarcoma tumors showed that serum and tissue concentrations of (R)-thalidomide were 40-50% greater than those of (S)-thalidomide.
- Co-administration of BCNU or cisplatin with thalidomide did not alter the concentration enantioselectivity in rats.
![Medchemexpress LLC 5-[(prop-2-yn-1-yl)amino]-2,3-dihydro-1H-isoindole-1,3-dione | 2357110-24-6 | MFCD34563706 | 98.0% | 311.29 g/mol | C16H13N3O4 | 50 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000284650.png-250.jpg)
Medchemexpress LLC 5-[(prop-2-yn-1-yl)amino]-2,3-dihydro-1H-isoindole-1,3-dione | 2357110-24-6 | MFCD34563706 | 98.0% | 311.29 g/mol | C16H13N3O4 | 50 MG
Thalidomide-5-NH-C-alkyne is an E3 ligase ligand-linker conjugate that contains a terminal alkyne for bioorthogonal conjugation. It is provided as a small-quantity research reagent intended for PROTAC development and target protein conjugation. Reported properties include a molecular formula of C16H13N3O4, a molecular weight of 311.29 g/mol, and a reported purity of 98.0%.
- Contains an E3 ligase ligand with a terminal alkyne for conjugation.
- Designed for PROTAC development and target protein degradation studies.
- Reported purity 98.0% suitable for research applications.
- Provided as a small-quantity reagent (50 mg) for synthetic chemistry workflows.
- Molecular formula C16H13N3O4; molecular weight 311.29 g/mol.
- Store and handle according to supplier safety data sheet recommendations.
Medchemexpress LLC 6h-Thieno[3,2-f]triazolo[4,3-a]diazepine-6-acetic acid, 4-(4-chlorophenyl)-2,3,9-trimethyl-, cyclopropyl ester, (6s)- | 3077900-08-1 | 98.31% | 440.95 | 1 ML
DDL-357 is a potent secreted clusterin enhancer. It reduces phospho-tau in the brain and improves memory in the murine 3xTg-AD model.
- Potent secreted clusterin enhancer.
- Reduces phospho-tau in brain.
- Improves memory in the murine 3xTg-AD model.
Medchemexpress LLC Thalidomide-O-amido-C4-NH2 (TFA) | 1799711-25-3 | MFCD31560484 | 99.9% | 516.42 g/mol | C21H23F3N4O8 | 1 G
Thalidomide-O-amido-C4-NH2 (TFA) is a thalidomide-derived cereblon ligand supplied as the trifluoroacetate salt and intended as a building block for E3 ligase ligand-linker conjugates and PROTAC research. The compound is provided as a solid research reagent with characterized purity, formula, and solubility data for in vitro and in vivo formulation.
- Intended for research use only.
- High purity 99.92%.
- Molecular weight 516.42 g/mol.
- Molecular formula C21H23F3N4O8.
- Soluble in DMSO (~42.86 mg/mL); multiple in vivo formulation protocols reported.
- Store dry at 4°C; in solvent store at -80°C for up to 6 months.
Medchemexpress LLC Thalidomide-O-amido-PEG2-C2-NH2 hydrochloride | 2376990-30-4 | 498.91 | 50 MG
Thalidomide-O-amido-PEG2-C2-NH2 hydrochloride incorporates an E3 ligase ligand and a linker, and can be an immunomodulator for the treatment of cancer. PROTACs, which contain two different ligands connected by a linker (one for an E3 ubiquitin ligase and the other for the target protein), exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Incorporates an E3 ligase ligand and a linker.
- Can be an immunomodulator for the treatment of cancer.
- Exploits the intracellular ubiquitin-proteasome system.
- Selectively degrades target proteins.
- For research use only.
Medchemexpress LLC Thalidomide-5-nh2-c8-nh2 tfa | 2097509-49-2 | 98.3% | 514.49 | 100 MG
Thalidomide-5-NH2-C8-NH2 TFA is a chemical compound that can be used for compound synthesis. It is for research purposes only and not for sale to patients.
- Appearance: Solid
- Color: Light yellow to green yellow
- Molecular Formula: C23H29F3N4O6
Medchemexpress LLC Thalidomide-5-Br | 26166-92-7 | 98.4% | 337.13 g/mol | C13H9BrN2O4 | 50 MG
Thalidomide-5-Br is a brominated thalidomide analogue supplied for biochemical research. It has a reported molecular weight of 337.13 g/mol and is supplied as an off-white to gray solid with reported purity around 98%.
- Used in research of inflammation, tumor biology, and neurology.
- Supplied as a solid suitable for formulation or dissolution in solvent for experimental use.
- Reported high purity for analytical and preclinical studies.
- Stable at room temperature for extended storage; in-solution storage requires low temperatures.
Medchemexpress LLC Thalidomide-O-PEG4-Boc | 2411681-87-1 | C28H38N2O11 | 50 MG
Thalidomide-O-PEG4-Boc is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide-based cereblon ligand and a linker used in PROTAC technology. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Synthesized E3 ligase ligand-linker conjugate
- Incorporates cereblon ligand
- Used in PROTAC technology
- Exploits intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
Medchemexpress LLC Thalidomide-O-C6-COOH | 2169266-69-5 | 99.3% | 25 MG
Thalidomide-O-C6-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the thalidomide based cereblon ligand and a linker used in PROTAC technology. This conjugate exploits the intracellular ubiquitin-proteasome system to selectively degrade target proteins and is for research use only.
- Synthesized E3 ligase ligand-linker conjugate
- Incorporates thalidomide-based cereblon ligand
- Used in PROTAC technology
- Exploits intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
- Related to cancer, cancer targeted therapy, cancer metabolism and metastasis
- Related to autophagy and apoptosis