Lactams
Medchemexpress LLC Tazobactam | 89786-04-9 | 99.9% | 1 ML
Tazobactam is a potent β-lactamases inhibitor and penicillin antibiotic. It exhibits antibacterial activity and can be used for pneumonia research.
- Potent β-lactamases inhibitor
- Penicillin antibiotic
- Antibacterial activity
- Can be used for pneumonia research
Apexbio Technology LLC Sulbactam sodium 69388-84-7 10mM (in 1mL H2O)
Sulbactam sodium is a competitive and irreversible inhibitor targeting -lactamase enzymes It functions predominantly through binding the active site of -lactamases thereby obstructing these enzymes from hydrolyzing -lactam antibiotics Widely employed in biomedical research Sulbactam sodium is utilized for evaluating bacterial resistance mechanisms characterizing susceptibility profiles of -lactamase-expressing clinical isolates and examining synergistic therapeutic combinations Moreover Sulbactam sodium itself exhibits antimicrobial activity notably against Acinetobacter species clinically resistant to common antibiotics In antibacterial assays against certain -lactamase-producing bacterial strains Sulbactam sodium typically demonstrates inhibitory effects at IC50 values ranging approximately from 5 to 25 g/mL depending upon specific experimental conditions
Apexbio Technology LLC Sulbactam 68373-14-8 10mM (in 1mL DMSO)
Sulbactam (CAS 68373-14-8) is a small-molecule inhibitor targeting bacterial -lactamase enzymes It is designed to inhibit -lactamase-mediated hydrolytic inactivation of -lactam antibiotics thereby enhancing antibiotic stability and efficacy Sulbactam exerts its biological activity primarily through competitive irreversible inhibition by covalently binding to the -lactamase active site Experimental studies report an IC50 value in the low micromolar range for inhibition of various bacterial -lactamase enzymes Based on these pharmacological properties Sulbactam holds research potential in investigating resistance mechanisms to -lactam antibiotics assessing combined therapeutic regimens and exploring novel clinical strategies for infections caused by -lactamase-producing pathogens
Medchemexpress LLC Sulbactam pivoxil | 69388-79-0 | MFCD00867003 | 98.0% | 347.38 g·mol⁻¹ | C14H21NO7S | 1 ML
Sulbactam pivoxil is the pivoxil prodrug of sulbactam, a β-lactamase inhibitor used in antibacterial research. It is supplied for research and analytical applications and is available as an analytical solid or as a ready-to-use 10 mM solution in DMSO.
- Available as solid and 10 mM solution in DMSO.
- Purity 98.0%.
- Molecular weight 347.38 g·mol⁻¹.
- Chemical formula C14H21NO7S.
- Recommended storage: powder -20°C for long term; in solvent -80°C for extended storage.
- Supplied with datasheet, certificate of analysis, and safety data sheet.
Medchemexpress LLC Sulbactam | 68373-14-8 | 100.0% | 100 MG
Sulbactam is a competitive, irreversible beta-lactamase inhibitor. It exhibits antimicrobial activity against multidrug-resistant (MDR) Acinetobacter calcoaceticus-Acinetobacter baumannii (Acb) complex and possesses a broad spectrum of antibacterial activity against Gram-positive and Gram-negative aerobic and anaerobic bacteria. It is suitable for use as a laboratory chemical and in the manufacture of substances.
- Competitive, irreversible beta-lactamase inhibitor
- Antimicrobial activity against multidrug-resistant (MDR) Acinetobacter calcoaceticus-Acinetobacter baumannii (Acb) complex
- Broad spectrum antibacterial activity
- Solid form, light yellow to yellow in color
- Suitable for laboratory chemical applications
- Melting point: 154-157°C
- Boiling point: 356°C at 760 mmHg
- Flash point: 297.1°C
- For research use only
U.S. Pharmacopeia Sulbactam, 68373-14-8, MFCD00867005, 250mg
Molecular formula C8H11NO5S, Molecular weight 233.24, Melting Point 298.4 - 303.8 °F (148 - 151 °C) (also reported as 170 °C), Synonyms: Penicillanic acid 1,1-dioxide. Cold Shipment Required
Apexbio Technology LLC Tazobactam (sodium salt) 89785-84-2 250mg
Tazobactam sodium salt (CAS 89785-84-2) is a small-molecule inhibitor targeting -lactamases It is designed to irreversibly bind to -lactamases thereby preventing the enzyme-mediated hydrolysis of -lactam antibiotics Tazobactam sodium salt exerts its biological activity primarily through -lactamase inhibition In microbiological assays tazobactam demonstrates intrinsic antibacterial activity against several Acinetobacter strains typically with MIC values of 8 mg/L (range 2 32 mg/L) Based on these pharmacological properties tazobactam sodium salt holds research potential in microbiological assessments and efficacy evaluations of -lactam antibiotic combinations
Medchemexpress LLC Thalidomide-pinacolborane | 2229725-98-6 | 97.0% | 384.19 | C19H21BN2O6 | 100 MG
Thalidomide-pinacolborane is a thalidomide analogue that incorporates a boronic pinacol ester (Bpin). It is used as an E3 ligase ligand in PROTAC research and as a boronate building block for cross-coupling chemistry. Intended for research use only.
- Contains a boronic pinacol ester (Bpin) suitable for Suzuki cross-coupling.
- Acts as a ligand for E3 ligase in PROTAC applications.
- Characterized identity with CAS 2229725-98-6 and molecular weight 384.19.
- Purity typically reported as 97.0% by supplier.
- Recommended storage under nitrogen at -20°C; in solvent, store at -80°C for up to 6 months.
Selleck Chemical LLC Laurocapram S4841-25mg
Laurocapram (N-Dodecylcaprolactam Azone N-0252 N-Lauryl caprolactam Tranzone) is a skin penetration enhancer that facilitates absorption of cutaneously applied substances