Lactams
Medchemexpress LLC Thalidomide-5-O-C13-NH2 hydrochloride | 99.9% | 508.05 g/mol | C26H38ClN3O5 | 10 MG
Thalidomide-5-O-C13-NH2 hydrochloride is a thalidomide-derived cereblon (CRBN) ligand supplied as the hydrochloride salt for research use in targeted protein degradation. It is intended for conjugation to target-binding ligands via linkers for PROTAC design and other bifunctional degrader constructs.
- High purity suitable for research assays (approximately 99.9%).
- Hydrochloride salt form for improved stability and handling.
- Compatible with linker conjugation for PROTAC synthesis.
- Recommended storage at -20°C; protect from light and oxygen.
- Supplied in small milligram quantities for exploratory studies.
Medchemexpress LLC Fc epsilon RIA/FCER1 10ug
Recombinant human Fc epsilon RIA (FCER1A) is the extracellular alpha chain of the high-affinity IgE receptor supplied as a His-SUMO-tagged recombinant protein. The lyophilized protein is intended for use in binding studies, ELISA, and other immunological or biochemical assays requiring the human FCER1A ectodomain.
- His-SUMO tagged protein for affinity purification and detection.
- Expressed in E. coli and supplied lyophilized for enhanced stability.
- Purity >95% as determined by reducing SDS-PAGE.
- Formulated with trehalose and EDTA for increased storage stability.
- Suitable for ELISA and binding assays; functional activity characterized.
- Recommended reconstitution at or above 100 μg/mL for optimal performance.
Medchemexpress LLC Laurocapram | 59227-89-3 | 281.48 | 1 ML
Laurocapram is a chemical penetration enhancer that increases the permeability of compounds through the skin and mucous membranes, improving their local or systemic efficacy. It enhances the skin permeability of various hydrophilic and lipophilic compounds. This product is provided as a 10 mM solution in 1 mL, suitable for research applications.
- Increases permeability of compounds through skin and mucous membranes.
- Improves local or systemic efficacy of compounds.
- Enhances skin permeability for both hydrophilic and lipophilic compounds.
- Synergizes with β-lactam antibiotics to improve antibacterial activity against S. aureus.
- Exhibits anti-infectious activity in MRSA-induced mouse pneumonia models.
- Ameliorates infection wounds in MRSA-administrated mouse skin infection models.
Medchemexpress LLC CD3 epsilon 1-27 pep 50ug | 50ug
CD3 epsilon is an important component of the TCR-CD3 complex on T lymphocytes and promotes TCR-mediated signaling When APC activates the TCR CD3 epsilon together with CD3D CD3G and CD3Z transmits signals across the cell membrane through ITAMs CD3 epsilon 1-27 peptide Protein Human (Biotinylated HEK293 hFc-Avi) is the recombinant human-derived CD3 epsilon 1-27 peptide protein expressed by HEK293 with C-Avi C-hFc labeled tag
Apexbio Technology LLC Sulbactam sodium,100mg CAS# 69388-84-7
Sulbactam sodium. Other sizes are also available. Please inqury us for quote.
Medchemexpress LLC Thalidomide-NH-PEG4-COOH | 2412056-48-3 | 96.7% | 521.52 | 50 MG
Thalidomide-NH-PEG4-COOH is an E3 ligase ligand-linker conjugate which can be used for synthesizing dCBP-1. dCBP-1 is a potent and selective heterobifunctional degrader of p300/CBP.
- E3 ligase ligand-linker conjugate
- Used for synthesizing dCBP-1
- Potent and selective heterobifunctional degrader of p300/CBP
- Purity of 96.7%
- Appearance: yellow to green (solid-liquid mixture)
- Store at -20°C, protect from light
Medchemexpress LLC Thalidomide-4-OH | 5054-59-1 | MFCD03699892 | 99.9% | 274.23 g/mol | C13H10N2O5 | 5 G
Thalidomide-4-OH is a 4-hydroxylated thalidomide derivative that serves as a cereblon (CRBN) ligand for targeted protein degradation research. It is commonly used as a building block in PROTAC design and medicinal chemistry studies and is supplied as a solid for laboratory research use only.
- Acts as a cereblon (CRBN) ligand suitable for PROTAC synthesis.
- 4-hydroxyl substitution enables linker attachment for conjugation.
- High purity supports reproducible conjugation and biological assays.
- Solid form allows convenient storage and handling.
- Useful for ligand optimization and E3 ligase recruitment studies.
Medchemexpress LLC Thalidomide-4-O-C14-NH2 hydrochloride | 99.9% | 522.08 | 5 MG
Thalidomide-4-O-C14-NH2 hydrochloride is a cereblon ligand derived from Thalidomide and is utilized for the recruitment of CRBN protein. It can be linked to a protein ligand via a linker to create PROTACs, which are relevant for research purposes.
- Thalidomide-based cereblon ligand
- Recruits CRBN protein
- Can be connected to a protein ligand by a linker to form PROTACs
- For research use only
Medchemexpress LLC Thalidomide-5-PEG2-Cl | 2230956-57-5 | 96.6% | 380.78 | 250 MG
Thalidomide-5-PEG2-Cl is a Thalidomide-based cereblon ligand that plays a crucial role in recruiting CRBN protein. It can be utilized to form PROTACs by linking to a target protein ligand. PROTACs are designed to selectively degrade target proteins within the intracellular ubiquitin-proteasome system by exploiting E3 ubiquitin ligase and target protein interactions.
- Thalidomide-based cereblon ligand
- Recruits CRBN protein
- Can be linked to form PROTACs
- Exploits ubiquitin-proteasome system
- Selectively degrades target proteins
Medchemexpress LLC Thalidomide-NH-C4-NH-Boc | 2093388-52-2 | 99.6% | 100 MG
Thalidomide-NH-C4-NH-Boc (compound 15) is a synthesized E3 ligase ligand-linker conjugate that incorporates a Thalidomide-based cereblon ligand and a linker utilized in PROTAC technology. It is intended for research use only.
- Synthesized E3 ligase ligand-linker conjugate.
- Incorporates Thalidomide based cereblon ligand.
- Uses a linker in PROTAC technology.
- High purity of 99.64%.