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Organic heterocyclic compounds that contain a cyclic amide; amide groups consist of a carbonyl carbon atom linked by a single bond to a nitrogen atom and either a hydrogen or a carbon atom. These compounds are the nitrogen analogs of lactones.
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
Thalidomide-NH-C6-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
Synthesized E3 ligase ligand-linker conjugate
Incorporates cereblon ligand and a linker used in PROTAC technology
For research use only
Exploits the intracellular ubiquitin-proteasome system
Selectively degrades target proteins
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
Thalidomide-NH-C6-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates a Thalidomide-based cereblon ligand and a linker commonly used in PROTAC technology. PROTACs are designed to exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. This product is intended for research use only and is not sold to patients.
Synthesized E3 ligase ligand-linker conjugate
Incorporates a thalidomide-based cereblon ligand
Features a linker used in PROTAC technology
Designed to exploit the ubiquitin-proteasome system
Selectively degrades target proteins
Molecular weight: 408.88
Chemical formula: C19H25ClN4O4
Appearance: Light yellow to yellow solid
Recommended storage: -20°C in sealed container, away from moisture and light
Long-term solvent storage: 6 months at -80°C or 1 month at -20°C
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
Thalidomide-NH-C6-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. This product is for research use only.
Synthesized E3 ligase ligand-linker conjugate
Incorporates Thalidomide based cereblon ligand
Used in PROTAC technology
Exploits intracellular ubiquitin-proteasome system
Selectively degrades target proteins
For research use only
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More