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Lactams

Organic heterocyclic compounds that contain a cyclic amide; amide groups consist of a carbonyl carbon atom linked by a single bond to a nitrogen atom and either a hydrogen or a carbon atom. These compounds are the nitrogen analogs of lactones.
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1

1,2,3,4-Cyclobutanetetracarboxdiimide 98.0+%, TCI America™

CAS: 4415-88-7 Molecular Formula: C8H6N2O4 Molecular Weight (g/mol): 194.146 InChI Key: NWRWMFOKSXWCHV-UHFFFAOYSA-N PubChem CID: 338831 SMILES: C12C(C3C1C(=O)NC3=O)C(=O)NC2=O

PubChem CID 338831
CAS 4415-88-7
Molecular Weight (g/mol) 194.146
SMILES C12C(C3C1C(=O)NC3=O)C(=O)NC2=O
InChI Key NWRWMFOKSXWCHV-UHFFFAOYSA-N
Molecular Formula C8H6N2O4
2

Medchemexpress LLC Thalidomide-4-O-C6-NH2 hydrochloride | 2245697-88-3 | 98.5% | C19H24ClN3O5 | 10MG
SDP

Thalidomide-4-O-C6-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate used in PROTAC research, notably as a component of the degrader dTAG-13 that directs FKBP12F36V and BET proteins for degradation. It is intended for laboratory research into E3 ligase recruitment, targeted protein degradation, apoptosis, and autophagy.

  • High purity suitable for research (98.5%).
  • Soluble in DMSO at 83.33 mg/mL (203.31 mM); ultrasonic assistance may be needed.
  • Engages cereblon for E3 ligase-mediated protein degradation.
  • Useful for PROTAC assembly and linker conjugation workflows.
  • Available in small research quantities to support assay development.
  • Recommended storage: 4°C sealed, away from moisture and light; in solvent, store at -80°C for long term.

ENCOMPASS_PREFERRED
3

Medchemexpress LLC Thalidomide-4-O-C6-NH2 hydrochloride | 2245697-88-3 | 98.5% | 409.86 | C19H24ClN3O5 | 5 MG
SDP

Thalidomide-4-O-C6-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate supplied as the hydrochloride salt for research use. It is used as a building block in PROTAC dTAG-13, a degrader of FKBP12F36V and BET proteins, and is provided with supporting analytical data and handling documentation.

  • Provided as the hydrochloride salt suitable for synthetic applications.
  • High purity (98.5% by HPLC) with supporting analytical data.
  • Analytical files include data sheet, COA, H NMR, and LCMS.
  • Available in multiple pack sizes from milligrams to grams.
  • Intended for research use only; not for human or therapeutic use.

ENCOMPASS_PREFERRED
4

eMolecules​ Medchem Express / Thalidomide-4-O-C6-NH2 (hydrochloride) / 5mg / 599150703 / HY-135250B / / 2245697-88-3 / [null] / 409.870 / C19H24ClN3O5

Medchem Express / Thalidomide-4-O-C6-NH2 (hydrochloride) / 5mg / 599150703 / HY-135250B / / 2245697-88-3 / [null] / 409.870 / C19H24ClN3O5

ENCOMPASS_PREFERRED