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Lactams

Organic heterocyclic compounds that contain a cyclic amide; amide groups consist of a carbonyl carbon atom linked by a single bond to a nitrogen atom and either a hydrogen or a carbon atom. These compounds are the nitrogen analogs of lactones.

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Medchemexpress LLC Thalidomide 4-chloro | 244057-36-1 | MFCD30188071 | >98.0% | 292.68 | C13H9ClN2O4 | 5 G
SDP

Thalidomide 4-chloro is a chlorinated thalidomide derivative that functions as an E3 ligase (cereblon) ligand/activator for research use. It is commonly used as a synthetic building block in PROTAC design and for studies involving CRBN recruitment, where the 4-chloro group can be substituted to create derivatives.

  • Functions as an E3 ligase (cereblon) ligand for biochemical studies.
  • Useful for PROTAC design and cereblon recruitment assays.
  • Enables further derivatization via substitution at the 4-chloro position.
  • Available in laboratory pack sizes suitable for synthesis and screening.
  • Analytical data and a product datasheet are available for reference.

ENCOMPASS_PREFERRED
2

Medchemexpress LLC Thalidomide 4-chloro | 244057-36-1 | MFCD30188071 | 96.0% | 292.68 g·mol⁻¹ | C13H9ClN2O4 | 500 MG
SDP

Thalidomide 4-chloro is a chlorinated derivative of thalidomide that acts as an E3 ligase activator for biochemical and cell-based research. It is commonly used as a research reagent and as a synthetic building block for further derivatization at the 4-chloro position, and is offered in lab-scale pack sizes with supporting product documentation.

  • Acts as an E3 ligase activator for protein degradation studies.
  • Serves as a synthetic intermediate for derivatization at the 4-chloro position.
  • Applicable in biochemical and cell-based assays.
  • Supplied in multiple lab-scale pack sizes suitable for research.
  • Molecular identity confirmed: CAS 244057-36-1, formula C13H9ClN2O4, MW 292.68 g·mol⁻¹.

ENCOMPASS_PREFERRED
3

Medchemexpress LLC Thalidomide 4-chloro | 244057-36-1 | MFCD30188071 | 96.0% | 292.68 g·mol⁻¹ | C13H9ClN2O4 | 1 G
SDP

Thalidomide 4-chloro is a chlorinated thalidomide derivative that functions as a cereblon (E3 ligase) ligand and E3 ligase activator. It is used in PROTAC development and as a synthetic building block for further derivatization via substitution at the 4-chloro position. The compound is supplied as a solid and is characterized for research applications.

  • Molecular formula: C13H9ClN2O4.
  • Molecular weight: 292.68 g·mol⁻¹.
  • CAS number: 244057-36-1.
  • Appearance: solid (powder).
  • Purity: 96.0%.
  • Intended use: E3 ligase (cereblon) ligand for PROTAC design and derivatization.
  • Storage: powder -20 °C (3 years) or 4 °C (2 years); in solvent -80 °C (6 months) or -20 °C (1 month).

ENCOMPASS_PREFERRED