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Organic heterocyclic compounds that consist of a cyclic carboximidic acid characterized by a carbon-nitrogen double bond within the ring; they are tautomeric with the lactams.
Cycloheximide is an antibiotic produced by Streptomyces sp. that activates against yeasts and fungi. It inhibits protein synthesis thru DNA translation arrest in eukaryotes. Cycloheximide also inhibits chain initiation and chain elongation by acting on 60S subunits of eukaryote ribosome.
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Also available in 10 mg 25 mg 50 mg 100 mg and bulk. Please contact Fisher for quotes. AP-C5 is a compound with selective inhibition of guanosine 3'5' cyclic monophosphate (cGMP)-dependent protein kinase II (cGKII) with a Pic50 value of 7.2 for cGMP and can be used in the study of diarrheal diseases. purity: 99%
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Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Complement C5-IN-1 is a small-molecule inhibitor of complement component 5 protein (C5). purity: 99%
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Porcine IgG Affinity Purified 1gm - Porcine IgG Affinity Purified from Innovative Research has been purified from normal Porcine Serum using Protein G affinity chromatography. This is a frozen liquid buffered in 0.02M Sodium Phosphate; 0.15M NaCl; pH 7.4 and a purity of >95%. This product is useful for ELISA, Western Blot, and as an isotype control. More Details Source Porcine Serum Purification IgG Fractionated Purity >95% Storage Conditions -70 C
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Cycloheximide cryst. pure Glutarimide antibiotic isolated from Streptomyces griseus; active against fungi and yeasts, but not against bacteria. Inhibits eukaryotic protein synthesis by blocking the translocation step in the elongation cycle (1,3,8). Blocks tra
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Cycloheximide cryst. pure Glutarimide antibiotic isolated from Streptomyces griseus; active against fungi and yeasts, but not against bacteria. Inhibits eukaryotic protein synthesis by blocking the translocation step in the elongation cycle (1,3,8). Blocks tra
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
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(S,R,S)-AHPC-C5-NH2 dihydrochloride is the dihydrochloride salt of an AHPC-derived E3 ligase ligand, provided as a solid for research use in studies of VHL E3 ubiquitin ligase recruitment and targeted protein degradation.
Dihydrochloride salt form for improved stability.
High purity of 97.8%.
Molecular weight 616.64 g/mol.
Molecular formula C28H43Cl2N5O4S.
Suitable as an E3 ligase ligand-linker component in PROTAC designs.
Storage: sealed, away from moisture; in solvent: -80°C up to 6 months, -20°C up to 1 month.
Documentation available: datasheet, COA, SDS.
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Pomalidomide-C5-azide is a cereblon (CRBN) E3 ubiquitin ligase ligand-linker conjugate bearing a terminal azide for bioconjugation. Supplied as a light yellow solid with high reported purity, it is intended for research use and is commonly used as a building block in PROTAC synthesis and click-chemistry workflows.
Azide functional group enables click chemistry conjugation.
Serves as a cereblon (CRBN) ligand-linker conjugate for degrader synthesis.
High purity suitable for research applications.
Light yellow solid for convenient handling and storage.
Soluble in DMSO at high concentration (100 mg/mL) with ultrasonic assistance.
Intended for research use only; not for clinical use.
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Dibromomaleimide-C5-COOH is a bifunctional dibromomaleimide linker used in antibody-drug conjugate synthesis to connect payloads such as MMAF. It is supplied as a white to off-white solid with high purity and is soluble in DMSO.
Bifunctional dibromomaleimide linker for ADC synthesis.
High purity (99.4%) suitable for research applications.
Molecular weight 369.01 g/mol and formula C10H11Br2NO4.
Soluble in DMSO at ≥100 mg/mL.
Available in small-scale quantities (5-200 mg) for conjugation workflows.
Store at 4°C under nitrogen; in solvent store at -80°C (6 months) or -20°C (1 month).
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