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An inhibitor of protein synthesis in eukaryotes (IC50 = 5-50 μM) that functions by interfering with translational elongation; can either induce or inhibit apoptosis depending on cell type
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Cycloheximide cryst. pure Glutarimide antibiotic isolated from Streptomyces griseus; active against fungi and yeasts, but not against bacteria. Inhibits eukaryotic protein synthesis by blocking the translocation step in the elongation cycle (1,3,8). Blocks tra
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Cycloheximide (CAS 66-81-9) is a small molecule inhibitor that specifically disrupts protein biosynthesis in eukaryotic cells by interfering with translational elongation at the ribosomal level It is widely employed in biomedical research to transiently block protein synthesis in vitro facilitating the study of cellular processes dependent on active translation Due to its cytotoxicity teratogenic potential and capacity to induce DNA damage cycloheximide is exclusively utilized for experimental research applications and inappropriate for clinical therapeutic use
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Complement C5/C5a Protein Mouse is a recombinant mouse complement component 5a (C5a) C5a is a potent pro-inflammatory mediator and acts as an essential part of the innate immune response[1]
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Complement C5/C5a Protein Mouse is a recombinant mouse complement component 5a (C5a) C5a is a potent pro-inflammatory mediator and acts as an essential part of the innate immune response[1]
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Cycloheximide is an antibiotic produced by Streptomyces sp. that activates against yeasts and fungi. It inhibits protein synthesis thru DNA translation arrest in eukaryotes. Cycloheximide also inhibits chain initiation and chain elongation by acting on 60S subunits of eukaryote ribosome.
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AP-C5 is a selective small-molecule inhibitor of cGMP-dependent protein kinase II (cGKII) used in cellular and biochemical research, including studies of diarrheal disease. It also contains an alkyne functional group that enables copper-catalyzed azide-alkyne cycloaddition (click chemistry) for probe conjugation.
Selective cGKII inhibition suitable for biochemical and cellular assays.
Click-chemistry compatible alkyne for facile probe conjugation.
High purity (>98%) for consistent experimental performance.
Solid, light yellow to light brown physical form for straightforward handling.
Stable when stored under recommended conditions for long-term use.
Good solubility in DMSO for preparation of screening solutions.
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A cell-permeable fungal toxin that is approximately 10 times more potent than cytochalasin B (Cat. No. 250233) in inhibiting actin filament function. Does not inhibit monosaccharide transport across cell membranes. Inhibits cytoplasmic division by blocking the formation of contractile microfilaments at 10 181M. Inactivates low conductance K channels. Also modulates CD4 cross-linking in T lymphocytes and increases intracellular Ca2 levels. Cytochalasin D also exhibits antibiotic and anti-tumor properties.
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Complement C5 is activated by C5 convertase inducing C5-C9 assembly to form the membrane attack complex The transient C6 binding site on C5b is critical for the formation of the cleavage complex Complement C5/C5a Protein Cynomolgus is the recombinant cynomolgus-derived Complement C5/C5a protein expressed by E coli with tag free
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Complement C5 is activated by C5 convertase inducing C5-C9 assembly to form the membrane attack complex The transient C6 binding site on C5b is critical for the formation of the cleavage complex Complement C5/C5a Protein Cynomolgus is the recombinant cynomolgus-derived Complement C5/C5a protein expressed by E coli with tag free
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