Lactims
Sigma Aldrich Fine Chemicals Biosciences InSolution Cytochalasin D
A cell-permeable fungal toxin that is approximately 10 times more potent than cytochalasin B (Cat. No. 250233) in inhibiting actin filament function. Does not inhibit monosaccharide transport across cell membranes. Inhibits cytoplasmic division by blocking the formation of contractile microfilaments at 10 181M. Inactivates low conductance K channels. Also modulates CD4 cross-linking in T lymphocytes and increases intracellular Ca2 levels. Cytochalasin D also exhibits antibiotic and anti-tumor properties.
Chem-Impex International, Inc. Cycloheximide (from Streptomyces griseus) | 66-81-9 | MFCD00082346 | 5G
Cycloheximide (from Streptomyces griseus), 66-81-9, MFCD00082346, 5G
Chem-Impex International, Inc. Cycloheximide (from Streptomyces griseus) | 66-81-9 | MFCD00082346 | 1G
Cycloheximide (from Streptomyces griseus), 66-81-9, MFCD00082346, 1G
Medchemexpress LLC Dibromomaleimide-C5-COOH (DBM-C5-COOH) | 1443214-97-8 | MFCD34705293 | 99.4% | 369.01 | C10H11Br2NO4 | 25 MG
Dibromomaleimide-C5-COOH is a bifunctional dibromomaleimide linker used for the construction of antibody-drug conjugates (ADCs), enabling attachment of payloads such as MMAF. It is supplied with high reported purity and is soluble in DMSO at high concentration.
- Bifunctional dibromomaleimide linker for ADC assembly.
- Can be used to connect MMAF to antibodies.
- High reported purity, 99.4%.
- Soluble in DMSO at ≥ 100 mg/mL.
- Available in small milligram package sizes for research use.
Medchemexpress LLC Glutarimide-isoindolinone-NH-PEG4-COOH | 2927334-86-7 | 99.5% | 507.53 | 100 MG
Glutarimide-Isoindolinone-NH-PEG4-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates a cereblon ligand and a linker used in PROTAC technology. Proteolysis Targeting Chimeras (PROTACs) consist of two different ligands connected by a linker; one ligand targets an E3 ubiquitin ligase, and the other targets the protein of interest. PROTACs function by leveraging the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Synthesized E3 ligase ligand-linker conjugate
- Incorporates a cereblon ligand
- Used in PROTAC technology
- Leverages the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
Medchemexpress LLC Complement C5/C5a C 100ug | 100ug
Complement C5 is activated by C5 convertase inducing C5-C9 assembly to form the membrane attack complex The transient C6 binding site on C5b is critical for the formation of the cleavage complex Complement C5/C5a Protein Cynomolgus is the recombinant cynomolgus-derived Complement C5/C5a protein expressed by E coli with tag free
Medchemexpress LLC HA/Hemagglutinin H7 50ug
The hemagglutinin (HA) protein attaches viral particles to host cells by binding to sialic acid-containing receptors and induces viral particle internalization through clathrin-dependent endocytosis HA also promotes an alternative clathrin- and caveolin-independent pathway for some virions HA/Hemagglutinin Protein H7N9 (AGI60301 sf9 His) is the recombinant Virus-derived HA/Hemagglutinin protein expressed by Sf9 insect cells with C-His labeled tag
Cayman Chemical CyclohexImIde 1g
An inhibitor of protein synthesis in eukaryotes (IC50 = 5-50 μM) that functions by interfering with translational elongation; can either induce or inhibit apoptosis depending on cell type