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Organic heterocyclic compounds that consist of a cyclic carboximidic acid characterized by a carbon-nitrogen double bond within the ring; they are tautomeric with the lactams.
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Complement C5/C5a Protein Mouse is a recombinant mouse complement component 5a (C5a) C5a is a potent pro-inflammatory mediator and acts as an essential part of the innate immune response[1]
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Cycloheximide (CAS 66-81-9) is a small molecule inhibitor that specifically disrupts protein biosynthesis in eukaryotic cells by interfering with translational elongation at the ribosomal level It is widely employed in biomedical research to transiently block protein synthesis in vitro facilitating the study of cellular processes dependent on active translation Due to its cytotoxicity teratogenic potential and capacity to induce DNA damage cycloheximide is exclusively utilized for experimental research applications and inappropriate for clinical therapeutic use
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7030B-C5 is a small-molecule PCSK9 inhibitor intended for preclinical research. It shows in vitro activity (IC50 = 1.61 μM) and has been reported to reduce plasma cholesterol and triglyceride levels in vivo. The compound is identified by CAS No. 370871-42-4 and is supplied at high purity for laboratory studies.
Small-molecule PCSK9 inhibitor with reported IC50 of 1.61 μM.
Demonstrated in vivo activity reducing plasma cholesterol and triglyceride levels.
High purity (99.78%), suitable for preclinical studies.
Characterized molecular weight 359.38 g/mol and formula C17H21N5O4.
Supplied as a 10 mg quantity for laboratory use.
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Glutarimide-Isoindolinone-NH-PEG4-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates a cereblon ligand and a linker used in PROTAC technology. It is intended for research use only.
This compound is designed to act as an E3 ligase ligand-linker conjugate.
It includes a cereblon ligand.
It contains a linker used in PROTAC technology.
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein, exploiting the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
The product has a purity of 99.5%.
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Cycloheximide is a protein synthesis inhibitor widely used in microbiology and cell biology laboratories as an antifungal agent. It functions by blocking the translocation step in eukaryotic ribosomes, effectively preventing protein synthesis in fungi and other eukaryotic organisms. This selective inhibition makes it useful in culture media where suppression of fungal growth is required while allowing bacterial growth to proceed. Cycloheximide is commonly incorporated into selective agar formulations and research protocols to control contamination by molds and yeasts. It is also used in molecular biology studies to investigate protein synthesis mechanisms and cellular responses to translational inhibition in experimental systems.
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Complement C5 is activated by C5 convertase inducing C5-C9 assembly to form the membrane attack complex The transient C6 binding site on C5b is critical for the formation of the cleavage complex Complement C5/C5a Protein Cynomolgus is the recombinant cynomolgus-derived Complement C5/C5a protein expressed by E coli with tag free
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The hemagglutinin (HA) protein attaches viral particles to host cells by binding to sialic acid-containing receptors and induces viral particle internalization through clathrin-dependent endocytosis HA also promotes an alternative clathrin- and caveolin-independent pathway for some virions HA/Hemagglutinin Protein H7N9 (AGI60301 sf9 His) is the recombinant Virus-derived HA/Hemagglutinin protein expressed by Sf9 insect cells with C-His labeled tag
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