Lactims

Medchemexpress LLC 4-[4-(1H-Imidazol-1-yl)phenyl]-N-2-propyn-1-yl-2-pyrimidinamine | 2234272-10-5 | 98.1% | C16H13N5 | 10MG

AP-C5 is a selective small-molecule inhibitor of cGMP-dependent protein kinase II (cGKII) used in cellular and biochemical research, including studies of diarrheal disease. It also contains an alkyne functional group that enables copper-catalyzed azide-alkyne cycloaddition (click chemistry) for probe conjugation.

• Selective cGKII inhibition suitable for biochemical and cellular assays.
• Click-chemistry compatible alkyne for facile probe conjugation.
• High purity (>98%) for consistent experimental performance.
• Solid, light yellow to light brown physical form for straightforward handling.
• Stable when stored under recommended conditions for long-term use.
• Good solubility in DMSO for preparation of screening solutions.

Medchemexpress LLC Pomalidomide-C5-azide | 2434629-02-2 | 97.5% | C18H20N6O4 | 10MG

Pomalidomide-C5-azide is an E3 ubiquitin ligase cereblon (CRBN) ligand-linker conjugate bearing a terminal azide for bioorthogonal click chemistry. It is used as a synthetic building block for PROTACs and related chemical biology probes, enabling attachment of linkers or payloads via azide-alkyne cycloaddition. Intended for research use only.

• Terminal azide suitable for copper-catalyzed and strain-promoted click reactions.
• Cereblon-binding ligand enables E3 ligase recruitment in degrader constructs.
• Useful building block for PROTAC synthesis and chemical biology probe development.
• High purity (≈97.5%) appropriate for research applications.
• Solid, light yellow appearance; store cold, protected from light, under inert gas when possible.