Lactones
eMolecules Delta-hexalactone | 823-22-3 | MFCD00083574 | 25g
Combi-Blocks | Delta-hexalactone | 25g | 448007435 | QF-0236 | 95.000 | 823-22-3 | MFCD00083574 | 114.144 | C6H10O2
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Apexbio Technology LLC Butyrolactone 3 778649-18-6 5mg
Butyrolactone 3 (CAS 778649-18-6) is a small-molecule inhibitor that targets the histone acetyltransferase Gcn5 a member of the GNAT family with specificity for histone H3 acetylation In vitro studies demonstrate that Butyrolactone 3 inhibits Gcn5 activity with an IC50 of 100 M while showing minimal inhibition of CBP The binding affinity of Butyrolactone 3 to Gcn5 is comparable to that of histone H3 and its inhibition is non-irreversible indicating it does not act via a Michael addition mechanism Structurally modification at position 2 has been suggested as a basis for structure activity relationship (SAR) studies Currently Butyrolactone 3 is utilized in preclinical research aimed at modulating Gcn5-mediated histone acetylation
Apexbio Technology LLC Ribonic acid gamma lactone 5336-08-3 500mg
Ribonic acid gamma lactone (CAS 5336-08-3) is a small-molecule inhibitor targeting -galactosidase derived from Escherichia coli It is designed to inhibit enzyme activity thereby interfering with substrate hydrolysis in carbohydrate metabolic pathways Ribonic acid gamma lactone exerts its biological activity primarily through competitive binding to the active site of -galactosidase In in vitro studies ribonic acid gamma lactone demonstrates inhibitory activity with an inhibitory constant (Ki) of approximately 26 mM Based on these pharmacological properties ribonic acid gamma lactone holds research potential in studies examining enzyme-substrate interactions and carbohydrate metabolism mediated by bacterial -galactosidase
eMolecules 5,6-DICHLORO-2-(HYDROXYMETHYL)BENZIMIDAZOLE | 6478-80-4 | MFCD09880338 | 1g
AstaTech | 5,6-DICHLORO-2-(HYDROXYMETHYL)BENZIMIDAZOLE | 1g | 569109698 | AC6539 | 95.000 | 6478-80-4 | MFCD09880338 | 217.050 | C8H6Cl2N2O
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Apexbio Technology LLC DL-Mevalonolactone 674-26-0 500mg
DL-Mevalonolactone (CAS 674-26-0) is the -lactone form of mevalonic acid serving as an intermediate in the mevalonate pathway This small molecule exhibits oral bioactivity in models of HMG-CoA reductase (HMGCR) mutations and statin-induced myopathy In preclinical studies DL-Mevalonolactone has been shown to induce inflammatory and oxidative stress responses decrease mitochondrial membrane potential and promote mitochondrial swelling It is utilized in research to investigate the biochemical consequences of mevalonate pathway modulation and mitochondrial dysfunction as well as the molecular mechanisms underlying statin-related muscle toxicity
Sigma Aldrich Fine Chemicals Biosciences delta-Decalactone natural, >=98%, FCC, FG | 705-86-2 | MFCD00006649 |
delta-Decalactone natural, >=98%, FCC, FG | Purity: >=98% | Mol Wt: 170.25 | 705-86-2 | MFCD00006649 |
Medchemexpress LLC Ampk gamma 1/beta 1/alpha 1 heterotrimer protein, human (sf9, His-GST) | >=98.0% | 160 kDa | 100 UG
The AMPK gamma 1/beta 1/alpha 1 Heterotrimer Protein, Human is a recombinant human-derived protein, expressed by Sf9 insect cells with N-His, N-GST labeled tag. As a crucial regulator of cellular energy metabolism, it is activated by low ATP levels, which enhances energy production while inhibiting biosynthetic processes and cell growth. The heterotrimer serves as the AMP/ATP-binding subunit of AMPK, influencing activation or inhibition through its gamma non-catalytic subunit.
- Recombinant human-derived protein
- Expressed by Sf9 insect cells
- N-His, N-GST labeled tag
- Regulator of cellular energy metabolism
- Activated by low ATP levels
- Enhances energy production
- Inhibits biosynthetic processes and cell growth
- Mediates binding to AMP, ADP, and ATP
- Modulates cellular polarity by remodeling the actin cytoskeleton
- Heterotrimeric composition includes alpha, beta, and gamma subunits
Medchemexpress LLC Not listed on product page; chemical name not found in accessible SDS | 1206731-57-8 | 98.4% | 458.55 | C27H30N4O3 | 1 ML
This compound is a potent, selective histone deacetylase 6 (HDAC6) inhibitor used in biochemical and cellular research to probe HDAC6-related pathways. It also shows activity against metallo-β-lactamase domain-containing protein 2 (MBLAC2) and is supplied as a ready-to-use solution for in vitro studies.
- Potent HDAC6 inhibition (IC50 = 0.40 nM).
- Also inhibits MBLAC2, enabling dual-target studies.
- High purity (98.4%) suitable for biochemical assays.
- Molecular weight 458.55, formula C27H30N4O3.
- Supplied as 10 mM 1 mL solution in DMSO; solid formats available.
- Soluble ≥100 mg/mL in DMSO; store solutions at -80°C for long-term stability.
eMolecules Alpha-bromo-gamma-butyrolactone | 5061-21-2 | MFCD00005387 | 5g
Combi-Blocks | Alpha-bromo-gamma-butyrolactone | 5g | 335350132 | QA-9875 | 96.000 | 5061-21-2 | MFCD00005387 | 164.986 | C4H5BrO2
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eMolecules ChemScene / tert-Butyl 2-(hydroxymethyl)-4-methylpiperazine-1-carboxylate / 100mg / 785210030 / CS-0608828 / 0.000 / 1450762-38-5 / MFCD28533519 / 230.308 / C11H22N2O3
ChemScene / tert-Butyl 2-(hydroxymethyl)-4-methylpiperazine-1-carboxylate / 100mg / 785210030 / CS-0608828 / 0.000 / 1450762-38-5 / MFCD28533519 / 230.308 / C11H22N2O3
Medchemexpress LLC δ-Decalactone | 705-86-2 | MFCD00006649 | 99.6% | 170.25 g/mol | C10H18O2 | 500 MG
δ-Decalactone (CAS 705-86-2) is a delta-lactone with a sweet, creamy, fruity aroma used in fragrance and flavor formulations, analytical reference standards, and laboratory research. It is supplied in research-scale quantities and is accompanied by certificate of analysis and safety data sheet documentation.
- Sweet, creamy, fruity aroma suitable for fragrance and flavor formulations.
- High purity (≈99.6%) for analytical and formulation consistency.
- Available in research-scale packages, including 500 mg and solution formats.
- Certificate of analysis and SDS available for quality and safety assurance.
- Molecular weight 170.25 g/mol for formulation calculations.