Lactones
eMolecules methyl trans-2-(hydroxymethyl)cyclopropanecarboxylate | 35501-83-8 | MFCD30830129 | 1g
Pharmablock | methyl trans-2-(hydroxymethyl)cyclopropanecarboxylate | 1g | 551099119 | PB97018 | | 35501-83-8 | MFCD30830129 | 130.143 | C6H10O3
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TARGETMOL CHEMICALS INC CYSTATHIONINE-GAMMA-LYAS 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg and bulk. Please contact Fisher for quotes. Cystathionine-(gamma)-lyase-IN-1 (SHIP-2a) is a selective inhibitor of cystathionine (gamma)-lyase (CSE) enzyme (IC50= 6.3 uM). purity: 99%
Medchemexpress LLC 11-Keto-beta-boswellic acid | 17019-92-0 | 470.68 | 1 MG
11-Keto-beta-boswellic acid is a pentacyclic triterpenic acid derived from the oleogum resin of the Boswellia serrata tree, commonly known as Indian Frankincense. It demonstrates anti-inflammatory activity primarily by inhibiting 5-lipoxygenase (5-LOX) and subsequent leukotriene and nuclear factor-kappa B (NF-κB) activation.
- Derived from Boswellia serrata (Indian Frankincense)
- Exhibits anti-inflammatory activity
- Inhibits 5-lipoxygenase (5-LOX)
- Inhibits nuclear factor-kappa B (NF-κB) activation
- For research use only
Medchemexpress LLC Gamma-secretase modulator 6 | 1255700-88-9 | 99.7% | 10 MG
Gamma-secretase modulator 6 is a high-purity research compound that modulates gamma-secretase activity and reduces Aβ42 secretion in cellular models (pIC50 8.1). It is provided as a solid or as a DMSO solution for preclinical biochemical and cellular research into Alzheimer's disease mechanisms.
- Inhibits Aβ42 secretion (pIC50 8.1).
- High purity suitable for research (99.68%).
- Available as solid and as a 10 mM DMSO solution.
- Molecular formula C25H26N6O2, molecular weight 442.51.
- Intended for preclinical and biochemical studies of amyloid processing.
Medchemexpress LLC Fc gamma RIIIA (CD16a) protein, rat | ≥98.0% | 10 UG
Recombinant rat Fc gamma RIIIA (CD16a) protein expressed in HEK293 cells with a C-terminal His tag, supplied as a solution. Intended for receptor-binding studies and immune-effector function assays (for example, ADCC), the product is characterized by lot documentation suitable for biochemical and assay applications.
- Recombinant rat sequence expressed in HEK293 cells.
- C-terminal His tag for detection and purification.
- Provided as a liquid solution for immediate use.
- High purity, ≥98.0% as determined by SDS-PAGE.
- Suitable for receptor binding and ADCC functional assays.
Medchemexpress LLC Fibrinogen gamma chain protein | >95.0% | 20 UG
Recombinant human fibrinogen gamma chain (fragment V169-L453) produced in Pichia pastoris for research applications in coagulation, wound repair, and cell-matrix interaction studies. The protein is tag-free, glycosylated, and supplied as a filtered solution formulated with stabilizers for laboratory assays.
- Recombinant human sequence (V169-L453).
- Expressed in P. pastoris.
- Tag-free and glycosylated.
- Supplied in PBS pH 7.4 with 5% trehalose, 5% mannitol, and 0.01% Tween 80.
- Purity >95% by reducing SDS-PAGE.
- Approximate molecular weight 32.2 kDa.
- Store at -80 °C; stable at -20 °C for 3 months after opening.
Medchemexpress LLC Fc gamma RIIB/CD32b protein, rat (HEK293-expressed, C-terminal His-tag) | 95.0% | 500 UG
Recombinant rat Fc gamma RIIB (CD32b) protein expressed in HEK293 cells with a C-terminal His tag, supplied as a purified reagent for immunology and Fc receptor-binding studies (500 μg format).
- Expressed in HEK293 cells for mammalian post-translational modifications.
- C-terminal His tag enables detection and purification.
- High purity (>95.0%) suitable for binding assays and biochemical analysis.
- Supplied in research-friendly formats including 500 μg.
- Useful for studies of IgG binding, Fc receptor signaling, and receptor-ligand interactions.
Medchemexpress LLC Fc gamma RIIIA/CD16a protein, rat | >95.0% | 10 UG
Recombinant rat Fc gamma RIIIA (CD16a) extracellular domain expressed in HEK293 cells, purified and supplied as a 0.22 μm-filtered PBS solution with a C-terminal His tag. Intended for in vitro Fc receptor binding studies, ADCC-related assays, and biophysical characterization.
- Expression system: HEK293 (mammalian)
- Tag: C-terminal His tag
- Format: 0.22 μm-filtered solution in PBS, pH 7.4
- Molecular weight: 28-33 kDa
- Purity: >95% by reducing SDS-PAGE
- Available sizes: microgram quantities (5, 10, 50, 100 μg)
- Applications: Fc receptor binding, ADCC assays, and biophysical studies
Medchemexpress LLC Fibrinogen gamma chain protein, human (P. pastoris) | >95.0% | 10 UG
Recombinant human fibrinogen gamma chain protein (V169-L453) expressed in P. pastoris. This tag-free protein is supplied as a filtered, stabilized solution for biochemical and cellular assays investigating fibrin formation, coagulation, and wound repair. Provided in microgram quantities for research use.
- Recombinant human sequence V169-L453 expressed in P. pastoris.
- Tag free, suitable for assays requiring unmodified protein.
- Approximate molecular weight 32.2 kDa.
- Purity >95.0% by reducing SDS-PAGE.
- Supplied in PBS pH 7.4 with 5% trehalose, 5% mannitol, 0.01% Tween 80.
- Stable when stored at -80°C; avoid repeated freeze-thaw cycles.
- Available in small microgram sizes for research applications.
Medchemexpress LLC Recombinant human AP-2 gamma (TFAP2C) protein, His-tag | >95.0% | 1 MG
Recombinant human AP-2 gamma (TFAP2C) protein fragment expressed in Escherichia coli and purified via affinity chromatography; provided as a high-purity His-tagged fragment suitable for biochemical characterization and antibody validation.
- Expressed in E. coli with an N-terminal His tag.
- Partial sequence L128-V223.
- Molecular weight approximately 10-14 kDa.
- Purity >95% as determined by reducing SDS-PAGE.
- Store at -20°C; freeze aliquots at -20°C or -80°C for extended storage.
- Suitable for biochemical assays, antibody validation, and protein interaction studies.
Medchemexpress LLC Fc gamma receptor IIa (CD32a) recombinant protein, rhesus macaque, C-terminal His tag | >95.0% | 100 UG
Recombinant extracellular fragment of rhesus macaque Fc gamma receptor IIa (CD32a), expressed in HEK293 cells and supplied with a C-terminal His tag. Provided lyophilized for use in binding and functional assays such as ELISA.
- Sequence range Q34-I217.
- Expression system HEK293 cells.
- Tag C-terminal His tag.
- Observed molecular weight ~25-35 kDa by SDS-PAGE.
- Purity >95% by reducing SDS-PAGE.
- Formulation lyophilized from PBS, pH 7.4.
- Recommended reconstitution concentration ≥100 μg/mL in ddH2O.
- Storage store at -20°C; after reconstitution 4°C for 1 week or -20°C long term; freeze aliquots for extended storage.
Medchemexpress LLC Fc gamma RIIIA/CD16a protein, rat (HEK293, C-His) | ≥98.0% | 100 UG
Recombinant rat Fc gamma RIIIA/CD16a protein expressed in HEK293 cells and supplied with a C-terminal His tag for detection and purification. The material is provided lyophilized with accompanying COA and datasheet and is intended for use in binding and functional assays, including ADCC-related studies.
- Recombinant rat FcγRIIIA/CD16a expressed in HEK293 cells.
- C-terminal His tag for purification and detection.
- High purity, ≥98.0% (COA) and >95% by reducing SDS-PAGE.
- Suitable for binding and ADCC-related functional assays; ED50 ≈93 ng/mL for human IgG1 binding.
- Lyophilized from PBS, pH 7.4; reconstitute to ≥100 μg/mL.
- Store at -20°C for long-term storage; 4°C stability for 1 week after reconstitution.
- Carrier protein recommended for reconstitution/storage (0.1% BSA, 5% HSA, 10% FBS, or 5% trehalose).
Medchemexpress LLC NH2 DOTA-GA | 1639843-65-4 | 518.56 | C21H38N6O9 | 50 MG
NH2 DOTA-GA is a DOTA-based bifunctional metal chelator used to prepare radionuclide drug conjugates (RDCs), with carboxylic acid groups capable of complexing metal ions such as Gd(III).
- Bifunctional DOTA chelator for radiolabeling of biomolecules.
- Suitable for preparation of radionuclide-drug conjugates.
- Molecular formula C21H38N6O9; molecular weight 518.56.
- Available as a 50 mg powder; stable for 3 years at -20°C when stored as recommended.
- Listed CAS number 1639843-65-4 for unambiguous identification.
Medchemexpress LLC Gamma-D-glutamylglycine | 6729-55-1 | 99.2% | 204.18 g·mol⁻¹ | C7H12N2O5 | 50 MG
gamma-DGG is a reversible, competitive AMPA receptor blocker used in neuropharmacology research to probe AMPA receptor-mediated synaptic transmission. It produces concentration-dependent blockade and reduces miniature excitatory postsynaptic current (mEPSC) amplitude, indicating a postsynaptic site of action.
- Competitive AMPA receptor antagonist for studying synaptic transmission
- Reversible action allows recovery after washout
- Concentration-dependent blockade suitable for dose-response experiments
- Reduces mEPSC amplitude, useful for postsynaptic mechanism studies
- High purity and stable solid form for reliable experimental results