Oxazinanes
Apexbio Technology LLC DMG-PEG 2000 250mg
DMG-PEG 2000 can be used in the preparation of liposomes for siRNA delivery to enhance in vitro transfection efficiency It can also be employed in the formulation of lipid nanoparticles (LNP) to improve their mucus penetration and delivery efficiency as well as for oral plasmid DNA delivery methods in vivo
AdipoGen GW311616A hydrochloride
Chemical. CAS 197890-44-1. Formula C19H31N3O4S . HCl. MW 397.5 . 36.5. Potent, selective intracellular neutrophil elastase NE, alpha-1-proteinase inhibitor by covalently binding to NE. Inhibits human neutrophil elastase HNE and is selective over other human serine proteases with IC50 values of 22nM for HNE, >100µM for trypsin, cathepsin G and plasmin, >3µM for chymotrypsin and tissue plasminogen activator. Specific beta-cell proliferation promoter. Similar to SerpinB1, which functions through its inhibiting activity of several proteases including neutrophil elastase, cathepsin G and proteinase-3. Reverses insulin resistance and body weight gain in HFD-fed mice, suggesting that the SerpinA1-NE system regulates AMPK signaling, fatty acid oxidation FAO and energy expenditure. The imbalance between SerpinA1 alpha1-antitrypsin A1AT and neutrophil elastase NE contributes to the development of obesity and related inflammation, insulin resistance and liver steatosis.
Cayman Chemical Riluzole (hydrochloride), Purity: ≥98%, CAS: 850608-87-6, 50 mg
A benzothiazole derivative with anti-excitotoxic effects that acts by blocking the presynaptic release of glutamate, indirectly antagonizing glutamate receptors, and inactivating neuronal voltage-gated Na+ channels (ED50 = 2.3 μM); suppresses glutamate-induced seizures in rats (ED50 = 3.2 mg/kg) and displays neuroprotective effects in hypoxic animals (ED50 = 4 mg/kg)
Medchemexpress LLC p-SCN-Bn-DOTA 50mg | 127985-74-4 | 50 MG
p-SCN-Bn-DOTA is a bifunctional chelating reagent that couples a para-isothiocyanatobenzyl reactive group to a DOTA macrocycle, enabling covalent conjugation to biomolecules and stable chelation of radiometals for radioimmunoconjugation and radiopharmaceutical research.
- Enables covalent attachment to proteins and antibodies via an isothiocyanate group.
- Provides stable complexation of radiometals through the DOTA chelator.
- High purity suitable for research-grade radioconjugation.
- Solid, easy-to-weigh form for small-scale conjugation workflows.
- Manufacturer provides SDS and datasheet for safe handling and use.
TARGETMOL CHEMICALS INC TIPIRACIL HYDROCHLORIDE 25MG
Also available in 5 mg 10 mg 50 mg 100 mg 200 mg 500 mg and bulk. Please contact Fisher for quotes. Tipiracil hydrochloride (MA-1 hydrochloride) is a thymidine phosphorylase inhibitor (TPI). Tipiracil hydrochloride is one of the active components in TAS-102 which is an anticancer drug candidate currently in clinical trials. purity: 99%
TARGETMOL CHEMICALS INC IDARUBICIN HYDROCHLORIDE 25MG
Also available in 5 mg 10 mg 50 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Idarubicin hydrochloride (Zavedos) a hydrochloride salt form of Idarubicin is a DNA topoisomerase II (topo II) inhibitor for MCF-7 cells ( IC50 3.3 ng/mL). purity: 99%
TARGETMOL CHEMICALS INC PAROXETINE 500MG
Also available in 25 mg 50 mg 100 mg and bulk. Please contact Fisher for quotes. Paroxetine is a inhibitor of serotonin uptake that is effective in the treatment of depression. purity: 99%
TARGETMOL CHEMICALS INC RHOSIN HYDROCHLORIDE 5MG
Also available in 1 mg 2 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Rhosin hydrochloride is an effective and specific RhoA subfamily Rho GTPases inhibitor which specifically binds to RhoA to inhibit RhoA-GEF interaction (Kd ~ 0.4 uM). Rhosin hydrochloride does not interact with Cdc42 or Rac1 nor the GEF LARG. Rhosin hydrochloride causes cell apoptosis. purity: 98%
Aobchem 4-Bromo-2-isopropyl-2H-1 2 3-triazole | ≥95% | CAS 1516805-15-4 | C5H8BrN3 | 250mg
4-Bromo-2-isopropyl-2H-1 2 3-triazole | ≥95% | CAS 1516805-15-4 | C5H8BrN3 | 250mg