Oxazinanes
Accela Chembio Inc 3-morpholinoaniline | 5g | 159724-40-0 | MFCD03197165 | 97+% | Shelf Life: 1800 Days | Light Sensitive/+4
3-morpholinoaniline | 5g | 159724-40-0 | MFCD03197165 | 97+% | Shelf Life: 1800 Days | Light Sensitive/+4
Medchemexpress LLC Decloxizine dihydrochloride | 13073-96-6 | 99.7% | C21H30Cl2N2O2 | 500 MG
Decloxizine dihydrochloride acts as a histamine 1 receptor antagonist and is intended for research use only. This compound presents as a white to off-white solid with a high purity of 99.69%.
- Antagonizes histamine 1 receptors
- Solid form
- High purity of 99.69%
- Suitable for various research applications
- Recommended storage at 4°C in sealed conditions, away from moisture
- Solutions can be stored at -80°C for up to 6 months or -20°C for 1 month
Selleck Chemical LLC MPTP hydrochloride S4732-1g
MPTP hydrochloride is a dopaminergic neurotoxin and cause selective destruction of dopaminergic neurons in animal models of parkinsonism MPTP hydrochloride induces apoptosis MPTP hydrochloride can be used to induce animal models of Parkinson s disease
Apexbio Technology LLC PD153035 hydrochloride 153436-54-5 10mM (in 1mL DMSO)
PD153035 hydrochloride (CAS 153436-54-5) is a small molecule inhibitor that targets the epidermal growth factor receptor (EGFR) tyrosine kinase by competitively binding to the ATP-binding site thereby suppressing EGFR kinase activity with an IC50 of 0 025 nM In various EGFR-overexpressing human tumor cell lines including A431 Difi DU145 MDA-MB-468 ME180 and C4i PD153035 inhibits EGF-dependent EGFR phosphorylation and subsequently reduces cell proliferation and colony formation with IC50 values ranging from 0 22 M to 2 5 M Additionally the compound partially inhibits the related HER2/neu receptor supporting its use in research exploring EGFR and HER2 signaling pathways and targeted cancer therapies
Medchemexpress LLC ML-7 hydrochloride | 110448-33-4 | C15H18ClIN2O2S | 5 MG
ML-7 hydrochloride is a naphthalene sulphonamide derivative that potently inhibits Myosin Light Chain Kinase (MLCK) with an IC50 of 300 nM. It also acts as an inhibitor of YAP/TAZ. In vitro studies indicate its ability to inhibit rabbit portal vein α1-adrenoceptor NSCC and attenuate Dexmedetomidine (DMT)-induced contraction. In vivo, ML-7 hydrochloride has been shown to reduce brain edema formation after traumatic brain injury in mice.
- Inhibits Myosin Light Chain Kinase (MLCK)
- Acts as an inhibitor of YAP/TAZ
- Inhibits rabbit portal vein α1-adrenoceptor NSCC
- Attenuates Dexmedetomidine (DMT)-induced contraction
- Reduces brain edema formation after traumatic brain injury in mice
Cayman Chemical SH1152 hydrochloride
A potent, specific, ATP-competitive, and cell permeable inhibitor of ROCK (Ki = 1.6 nM); more potent inhibitor of ROCK than either Y-27632 (Ki = 140 nM) or HA-1077 (Ki = 330 nM); poorly inhibits PKA, PKC, and MLCK
Selleck Chemical LLC Celiprolol hydrochloride
Celiprolol is a 1-adrenoceptor antagonist with partial 2 agonist activity
Selleck Chemical LLC KHS101 hydrochloride
KHS101 is a small-molecule inhibitor of TACC3 which is a key component of centrosome-microtubule dynamic networks
Medchemexpress LLC Bersiporocin | 2241808-52-4 | 99.0% | 328.24 g/mol | C15H19Cl2N3O | 5 MG
Bersiporocin is a small-molecule prolyl-tRNA synthetase (PRS) inhibitor used in preclinical research to study antifibrotic mechanisms and collagen synthesis modulation. Supplied as a high-purity solid, it is suitable for in vitro and in vivo formulation with documented solubility in DMSO and recommended low-temperature storage for stability.
- High purity (≈99%) suitable for research applications.
- Potent PRS inhibition for antifibrotic research.
- Soluble in DMSO at high concentration for in vitro studies.
- Available in small mg quantities for early-stage experiments.
- Stability data provided for low-temperature storage.
Medchemexpress LLC Quizartinib dihydrochloride | 1132827-21-4 | 99.8% | 633.59 g·mol⁻1 | C29H34Cl2N6O4S | 5 MG
Quizartinib dihydrochloride is the dihydrochloride salt form of quizartinib, a second-generation, highly selective type II FLT3 tyrosine kinase inhibitor used in preclinical oncology research. It demonstrates low-nanomolar potency against FLT3 and FLT3-ITD and is employed in cellular assays and medicinal chemistry applications, including degrader design. The material is supplied at research scale with high reported purity.
- High potency FLT3 inhibition in the low-nanomolar range.
- Suitable for in vitro and preclinical AML models.
- Compatible with PROTAC linker chemistry and conjugation studies.
- Supplied as the dihydrochloride salt for improved solubility.
- High purity suitable for biochemical and cellular assays.
- Available in multiple small research pack sizes.
TARGETMOL CHEMICALS INC Vazegepant hydrochloride 1MG
Also available in 1 mL, 5 mg, 10 mg, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. Vazegepant hydrochloride (Vazegepant HCl) is the first intranasal gepant for the acute treatment of migraine and has announced a positive phase II/III study. Purity 99.56%
Cayman Chemical EthylLNIO hydrochloride
A modestly selective NOS inhibitor with Ki values for inhibition of nNOS, eNOS, and iNOS of 5.3, 18, and 12 µM, respectively; however, does not show biologically significant selectivity for nNOS over eNOS, and instead favors iNOS (Ki/Km = 3.79, 5, and 0.96 µM, respectively)
Medchemexpress LLC Landiolol hydrochloride | 144481-98-1 | MFCD01937430 | >98.0% | 546.05 | C25H40ClN3O8 | 50 MG
Landiolol hydrochloride is an analytical standard of an ultra-short-acting, highly β1-selective beta-adrenergic receptor antagonist supplied for research and analytical use, suitable for quantification, calibration, and method development in biochemical and pharmacological studies.
- Analytical standard grade for research and method development.
- High purity, >98% (HPLC) as reported by suppliers.
- Molecular formula C25H40ClN3O8 and molecular weight 546.05 Da.
- CAS number 144481-98-1 for unambiguous identification.
- Supplied in small quantities suitable for analytical use, e.g. 50 MG.
- Intended for calibration, quantification, and analytical characterization in biological and formulation samples.
- Store under conditions specified in the certificate of analysis.