Oxazinanes
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Cayman Chemical CP 24,879 (hydrochloride), Purity: ≥98%, CAS: 10141-51-2, 10 mg
A Δ5/Δ6 desaturase inhibitor; reduces liver arachidonate content by ~50% in mice at 3 mg/kg; increases mead acid content and inhibits leukotriene C4 synthesis in murine mastocytoma cells at 5 µM
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Cayman Chemical O-2545 (hydrochloride), Purity: ≥98%, CAS: 874745-43-4, 5 mg
A potent water-soluble agonist of CB1 and CB2 receptors with Ki values of 1.5 and 0.32 nM, respectively; when dissolved in saline, is highly efficacious in mouse behavioral models when administered either intravenously or intracerebroventricularly
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Cayman Chemical Leelamine (hydrochloride), Purity: ≥98%, CAS: 16496-99-4, 50 mg
The hydrochloride of leelamine, an inhibitor of pyruvate dehydrogenase kinase.
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Cayman Chemical (S)-H-1152 (hydrochloride), Purity: ≥95%, CAS: 451462-58-1, 1 mg
A potent, specific, ATP-competitive, and cell permeable inhibitor of ROCK (Ki = 1.6 nM); more potent inhibitor of ROCK than either Y-27632 (Ki = 140 nM) or HA-1077 (Ki = 330 nM); poorly inhibits PKA, PKC, and MLCK
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