Oxazinanes
TARGETMOL CHEMICALS INC RAC-ACOLBIFENE 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. (Rac)-Acolbifene (EM-343) is the racemic form of Acolbifene. Acolbifene is a estrogen receptor antagonist. (Rac)-Acolbifene exhibits anti-estrogenic and estrogenic activities. (Rac)-Acolbifene contains a piperidine ring and exhibits good pharmacological profilerelative binding affinity (RBA)=380. purity: 98%
Cayman Chemical Leelamine hydrochloride
The hydrochloride of leelamine, an inhibitor of pyruvate dehydrogenase kinase.
TARGETMOL CHEMICALS INC UPGL00004 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. UPGL00004 is a potent glutaminase C (GAC) inhibitor with an IC50 of 29 nM. Kd of UPGL00004 for GAC was 27 nM. UPGL00004 has a strong inhibitory effect on the proliferation of highly aggressive triple negative breast cancer cell lines. purity: 97%
TARGETMOL CHEMICALS INC MRT 67307 DIHYDROCHLORID 5MG
Also available in 1 mg 10 mg 50 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. MRT 67307 dihydrochloride is a dual inhibitor of the IKK(epsilon) and TBK-1 with IC50s of 160 and 19 nM respectively. MRT67307 dihydrochloride also inhibits ULK1 and ULK2 with IC50s of 45 and 38 nM respectively. MRT67307 dihydrochloride also blocks autophagy in cells. purity: 98%
Cayman Chemical SKF 96365 hydrochloride
Inhibits the receptor-mediated influx of calcium via voltage-gated calcium channels (IC50 = 10 µM); inhibits the acetylcholine-induced depolarization of circular smooth muscle in a dose-dependent manner at 3-50 µM
