Oxazinanes
Selleck Chemical LLC Iptacopan Hydrochloride
Iptacopan Hydrochloride is a first-in-class orally administered potent and highly selective factor B inhibitor with an IC50 of 12 nM and a Kd value of 7 9 nM Iptacopan exhibits excellent selectivity over other proteases affording IC50s of 30 M across a panel of 41 human proteases
Cayman Chemical GW 3965 hydrochloride
An orally-active agonist of LXRα and LXRβ, activating the human isoforms with EC50 values of 190 and 30 nM, respectively; alters LXR-regulated gene expression in mice and rats, affecting pathways related to glucose and lipid metabolism
TARGETMOL CHEMICALS INC PENTAGASTRIN 25MG
Also available in 5 mg 10 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Pentagastrin (ICI-50123) is a synthetic polypeptide that has effects like gastrin when given parenterally which can cause the secretion and synthesis of salivary proteins. purity: 99%
![eMolecules 850583-75-4 | 3,6-Di(2-thienyl)-2,5-dihydropyrrolo[3,4-c]pyrrole-1,4-dione | Combi-Blocks, Inc. | MFCD20257907 | 300.350 | C14H8N2O2S2 | 98.000 | O=C1NC(=C2C(=O)NC(=C12)c1cccs1)c1cccs1 | 25g | 569293009](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502192398.JPG-250.jpg)
eMolecules 850583-75-4 | 3,6-Di(2-thienyl)-2,5-dihydropyrrolo[3,4-c]pyrrole-1,4-dione | Combi-Blocks, Inc. | MFCD20257907 | 300.350 | C14H8N2O2S2 | 98.000 | O=C1NC(=C2C(=O)NC(=C12)c1cccs1)c1cccs1 | 25g | 569293009
3,6-Di(2-thienyl)-2,5-dihydropyrrolo[3,4-c]pyrrole-1,4-dione | Combi-Blocks, Inc. | 850583-75-4 | MFCD20257907 | 300.350 | C14H8N2O2S2 | 98.000 | O=C1NC(=C2C(=O)NC(=C12)c1cccs1)c1cccs1 | 25g | 569293009
Selleck Chemical LLC Fendiline hydrochloride S5279-25mg
Fendiline hydrochloride is the hydrochloride salt form of Fendiline which is an L-type calcium channel blocker and also a specific inhibitor of K-Ras plasma membrane targeting with no detectable effect on the localization of H- and N-Ras
Medchemexpress LLC Rhodamine B isothiocyanate | 36877-69-7 | MFCD00041787 | 98.0% | 536.09 g/mol | C29H30ClN3O3S | 5 MG
Rhodamine B isothiocyanate is a xanthene-derived fluorescent labeling reagent containing an isothiocyanate functional group for covalent conjugation to primary amines. Provided as a solid, it produces strong red fluorescence for biochemical labeling, microscopy, and fluorescence assays, and is suitable for preparing labeled proteins, peptides, and other biomolecules.
- Provides bright red fluorescence for sensitive detection and imaging.
- Reacts with primary amines via isothiocyanate chemistry for stable covalent labeling.
- High purity (~98.0%) for reproducible conjugation results.
- Solid form allows easy handling and long-term storage when protected from light.
- Compatible with common fluorescence detection systems and imaging filters.
Selleck Chemical LLC Arecaidine hydrochloride
Arecaidine hydrochloride a constituent of the nut of Areca catechu inhibits the uptake of GABA and beta-alanine but not that of glycine
Selleck Chemical LLC NADPH tetrasodium salt-250MG
NADPH tetrasodium salt is a ubiquitous coenzyme that acts as an electron donor in many reactions utilizing dehydrogenase and reductase enzymes It plays a crucial role as a cofactor in the biosynthesis of nucleotides proteins and fatty acids It is essential for neutralizing elevated levels of reactive oxygen species (ROS) generated by increased metabolic activity
c1ccccc1 | 1g | 268500009](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502178647.JPG-250.jpg)
eMolecules 914299-79-9 | (S)-3-PHENYLMORPHOLINE | AstaTech | MFCD11016232 | 163.220 | C10H13NO | 95.000 | C1COC[C@@H](N1)c1ccccc1 | 1g | 268500009
(S)-3-PHENYLMORPHOLINE | AstaTech | 914299-79-9 | MFCD11016232 | 163.220 | C10H13NO | 95.000 | C1COC[C@@H](N1)c1ccccc1 | 1g | 268500009
AdipoGen CX-4945 HCl
Chemical. CAS 1009820-21-6 free acid. Formula C19H12ClN3O2 . HCl. MW 349.8 . 36.5. Synthetic. Orally active, potent and selective ATP-competitive inhibitor of the protein kinase CK2 IC50=1nM. Anticancer compound. Inhibits proliferation in a panel of cancer cell lines that overexpress CK2. Inhibited migration, blocks survival and induces apoptosis in cancer stem cells, glioblastomas and leukemia cells. Shown to decrease the glucose metabolism in cancer cells. Potent inhibitor of Cdc2-like kinases Clks in vitro, consequently interfering with alternative splicing. Potent ATP-competitive inhibitor of DYRK1A IC50=6.8 nM, involved in neurodegenration-associated diseases. CK2alpha deletion selectively increased M3 muscarinic receptors M3Rs-mediated insulin secretion from pancreatic islets. Promoted cAMP-induced thermogenesis in white adipocytes. CK2 inhibition ameliorates diet-induced obesity and insulin resistance in mice in vivo by promoting UCP1-dependent thermogenesis.