Oxazinanes
Medchemexpress LLC TP-238 hydrochloride 10mM 1mL | 2415263-05-5 | 1 ML
TP-238 hydrochloride is the hydrochloride salt of TP-238, a potent and selective dual CECR2/BPTF probe used for biochemical and cellular studies of epigenetic reader domains. Offered as a 10 mM solution in DMSO and as solids, it is suitable for target validation and assay development.
- Potent dual CECR2 and BPTF inhibitor with IC50s of 30 nM and 350 nM.
- Additional inhibitory activity against BRD9 (pIC50 5.9).
- Available as a 10 mM DMSO solution (1 mL) and as solids (5-500 mg).
- Typical purity around 98.8% (source contains conflicting purity statements).
- Molecular weight 495.04 and formula C22H31ClN6O3S.
- Store at -20°C under inert atmosphere; in solvent store at -80°C up to 6 months.
Cayman Chemical Oxybutynind10 hydrochloride
An internal standard for the quantification of oxybutynin by GC- or LC-MS
TARGETMOL CHEMICALS INC Adatanserin hydrochloride 1MG
Also available in 5 mg, 10 mg, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. Adatanserin hydrochloride (WY50324 hydrochloride) is a novel 5-HT(1A)/5-HT(2) receptor ligand with potential neuroprotective effects and inhibition of ischemic efflux of endogenous amino acids, which can be used in the study of depression and anxiety disorders. Purity 99.64%
Cayman Chemical SH1152 hydrochloride
A potent, specific, ATP-competitive, and cell permeable inhibitor of ROCK (Ki = 1.6 nM); more potent inhibitor of ROCK than either Y-27632 (Ki = 140 nM) or HA-1077 (Ki = 330 nM); poorly inhibits PKA, PKC, and MLCK
Medchemexpress LLC 3-(3-methyl-3H-diazirin-3-yl)propanoic acid | 25055-86-1 | MFCD19228230 | >97.0% | 128.13 g/mol | C5H8N2O2 | 250 MG
3-(3-methyl-3H-diazirin-3-yl)propanoic acid is a diazirine-containing carboxylic acid used as a chemical intermediate and photoreactive building block in organic and medicinal chemistry. It is employed to introduce a photo-crosslinking diazirine moiety into target molecules for probe synthesis and study of biomolecular interactions.
- Small, 128.13 g/mol carboxylic acid with formula C5H8N2O2.
- Contains a diazirine photoreactive group for carbene generation upon irradiation.
- Useful as a synthetic intermediate for probe and drug analog synthesis.
- Enables photoaffinity labeling and covalent capture of interaction partners.
- Typically supplied at high purity suitable for research applications (suppliers list ≥97%).
TARGETMOL CHEMICALS INC Neticonazole Hydrochloride
Also available in 25 mg, 50 mg, 200 mg and bulk. Please contact Fisher for quotes. Neticonazole Hydrochloride is an imidazole antifungal for the treatment of fungal skin infections. Neticonazole is reported as a potent exosome inhibitor which can block the activity of exosomes. Purity 99.84%
Selleck Chemical LLC Ksg hydrochloride hydrate
Kasugamycin (Ksg) hydrochloride hydrate an antibiotic which binds both the 30S and 70S ribosome specifically inhibits translation initiation of canonical but not of leaderless messenger RNAs
Medchemexpress LLC 5,6-dihydro-5-fluorouracil | 696-06-0 | MFCD00871150 | 99.9% | 132.09 g·mol⁻¹ | C4H5FN2O2 | 5 MG
5,6-Dihydro-5-fluorouracil (5-DHFU) is the active metabolite of the chemotherapy prodrug 5-fluorouracil. Supplied as a white to off-white solid for research use, it is used in metabolic profiling, enzyme assays, and studies of drug metabolism and pharmacokinetics. The material is suitable as a reference standard in biochemical and pharmacological investigations.
- High purity suitable for analytical and preparative studies.
- Available in small milligram quantities for early-stage research.
- Solid form facilitates weighing, storage, and transport.
- Documented chemical identifiers support traceability.
- Commonly used as a reference in metabolic and enzymatic assays.
Medchemexpress LLC Cholest-5-en-3-yl [(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]glycinate, trifluoroacetate | 1609010-59-4 | >95.0% | 886.1 g·mol⁻¹ | C43H73F6N5O7 | 5 MG
2H-Cho-Arg (trifluoroacetate) is a steroid-based cationic lipid that couples a 2H-cholesterol skeleton to an L-arginine head group. It forms complexes with plasmid DNA and is used to facilitate gene transfection in cultured cells.
- Steroid-based cationic lipid with a 2H-cholesterol skeleton and L-arginine head group.
- Forms stable complexes with plasmid DNA, reducing DNA migration in electrophoretic assays.
- Facilitates transfection of reporter genes in cell lines such as H1299.
- Cellular uptake involves lipid raft and caveolae-mediated endocytosis pathways.
- Supplied as the trifluoroacetate salt in solution; recommended storage -20 °C.
- Reported purity greater than 95%.
Medchemexpress LLC Vacquinol-1 dihydrochloride (NSC13316 dihydrochloride) | 2309312-85-2 | 99.7% | 425.78 | 100 MG
Vacquinol-1 (NSC13316) dihydrochloride is a MKK4-specific activator that activates MAPK pathways. It specifically induces human glioblastoma cell (GC) death, attenuates tumor progression, and prolongs survival in a glioblastoma multiforme (GBM) mouse model. Vacquinol-1 dihydrochloride also induces apoptosis in hepatocellular carcinoma (HCC) cells.
- Activates MAPK pathways
- Induces human glioblastoma cell death
- Attenuates tumor progression
- Prolongs survival in a glioblastoma multiforme mouse model
- Induces apoptosis in hepatocellular carcinoma cells
Medchemexpress LLC Decloxizine dihydrochloride | 13073-96-6 | 99.69% | C21H30Cl2N2O2 | 100 MG
Decloxizine dihydrochloride is a histamine 1 receptor antagonist.
- H1 receptor antagonist.
Selleck Chemical LLC Tulobuterol hydrochloride
Tulobuterol is a long-acting 2-adrenergic receptor agonist that has bronchodilatory anti-inflammatory and antiviral activities