Oxazinanes
Medchemexpress LLC Elacestrant dihydrochloride | 1349723-93-8 | 99.5% | 531.56 | 5 MG
Elacestrant dihydrochloride is an orally available and selective estrogen receptor degrader (SERD) that inhibits the growth of ER+ breast cancer cell lines both in vitro and in vivo. It has IC50s of 48 nM for ERα and 870 nM for ERβ. This product is for research use only and not sold to patients.
- Orally available and selective estrogen receptor degrader
- Inhibits the growth of ER+ breast cancer cell lines
- For research use only
- Appearance: white to off-white solid
- Shipped at room temperature
- Stored at 4°C, sealed, away from moisture
- In solvent, stored at -80°C for 6 months or -20°C for 1 month
eMolecules Pharmablock cyclohexane-1 2-dione 500mg 812210731 PBTEN8012 0 000 765-87-7 MFCD00001648 112 128 C6H8O2
Pharmablock cyclohexane-1 2-dione 500mg 812210731 PBTEN8012 0 000 765-87-7 MFCD00001648 112 128 C6H8O2
TARGETMOL CHEMICALS INC RS 17053 HYDROCHLORIDE 5MG
Also available in 2 mg 50 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. RS 17053 hydrochloride is a potent and selective antagonist of (alpha)1A adrenoceptor. RS 17053 hydrochloride exhibits a pKi value of 9.1 in native cell membrane and a pA2 value of 9.8 in functional assays. purity: 99%
Medchemexpress LLC Pyrithioxin dihydrochloride | 10049-83-9 | 98.0% | 500 MG
Pyrithioxin (Pyritinol) dihydrochloride is the dihydrochloride salt of Pyrithioxin. Pyrithioxin (Pyritinol) is an orally active neurodynamic compound. Pyrithioxin can promote the metabolism of glucose and amino acids, increase carotid blood flow and improve cerebral blood flow. Pyrithioxin exhibits anti-inflammation, anti-tumor and neuroprotective effect. Pyrithioxin can be used for the researches of cancer, inflammation, immunology, metabolic and neurological disease such as cerebral infarct, epilepsy, fibrosarcomas and rheumatoid polyarthritis.
- Promotes metabolism of glucose and amino acids
- Increases carotid blood flow and improves cerebral blood flow
- Exhibits anti-inflammation effects
- Exhibits anti-tumor effects
- Provides neuroprotective effects
eMolecules 4-Morpholin-4-ylmethyl-benzylamine dihydrochloride | 1414958-29-4 | MFCD22689206 | 5g
J & W PharmLab, LLC | 4-Morpholin-4-ylmethyl-benzylamine dihydrochloride | 5g | 249976342 | 20R0898S | 96.000 | 1414958-29-4 | MFCD22689206 | 279.210 | C12H20Cl2N2O
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Medchemexpress LLC (6S)-CP-470711 | 300552-09-4 | 98.8% | 358.44 | C18H26N6O2 | 10 MG
(6S)-CP-470711 is a research-grade small-molecule inhibitor of sorbitol dehydrogenase (SDH). Supplied as a powder in small research pack sizes, it has low-nanomolar potency against human and rat SDH and is intended for laboratory research use.
- Low-nanomolar SDH inhibitor (human IC50 19 nM; rat IC50 27 nM).
- Powder form suitable for storage and handling.
- Purity 98.75% by manufacturer specification.
- Chemical formula C18H26N6O2; molecular weight 358.44.
- Available in small pack sizes, including a 10 mg pack.
- Storage: powder -20°C for up to 3 years; in solvent -80°C for up to 6 months.
eMolecules Combi-Blocks Inc 3-(Benzyloxy)oxan-4-one 250mg 726031001 QE-5149 95 000 1351450-56-0 MFCD28155161 206 241 C12H14O3
Combi-Blocks Inc 3-(Benzyloxy)oxan-4-one 250mg 726031001 QE-5149 95 000 1351450-56-0 MFCD28155161 206 241 C12H14O3
![Medchemexpress LLC Mal((3S,3aR,6S,6aR)-hexahydrofuro[3,2-b]furan-3,6-diamine-PEG12)-β-glu-pab-exatecan | 3059991-66-8 | 96.1% | 1852.91 | C87H118FN9O34 | 25 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000203645.png-250.jpg)
Medchemexpress LLC Mal((3S,3aR,6S,6aR)-hexahydrofuro[3,2-b]furan-3,6-diamine-PEG12)-β-glu-pab-exatecan | 3059991-66-8 | 96.1% | 1852.91 | C87H118FN9O34 | 25 MG
Mal((3S,3aR,6S,6aR)-hexahydrofuro[3,2-b]furan-3,6-diamine-PEG12)-β-glu-pab-exatecan is an exatecan-containing ADC linker-payload intermediate intended for research use. It is supplied as an off-white to light yellow solid and is characterized by a high molecular weight and analytical purity suitable for biochemical and ADC development studies.
- Molecular weight: 1852.91
- Chemical formula: C87H118FN9O34
- Purity: 96.1% (HPLC)
- Appearance: off-white to light yellow solid
- Storage: store at -20°C; in solvent, -80°C for up to 6 months
Medchemexpress LLC (3R,5R,6S)-Atogepant | 99.55% | 603.52 | 50 MG
(3R,5R,6S)-Atogepant, also known as (3R,5R,6S)-MK-8031, is an enantiomer of Atogepant. This compound acts as a calcitonin gene-related peptide receptor (CGRP) antagonist and is utilized in researching migraine.
- Enantiomer of Atogepant
- Calcitonin gene-related peptide receptor (CGRP) antagonist
- Used for researching migraine
- High purity of 99.55%
- Molecular weight: 603.52
- Store powder at -20°C for up to 3 years
- Store in solvent at -80°C for up to 6 months or -20°C for 1 month
- Soluble in DMSO (50 mg/mL)
TARGETMOL CHEMICALS INC UPGL00004 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. UPGL00004 is a potent glutaminase C (GAC) inhibitor with an IC50 of 29 nM. Kd of UPGL00004 for GAC was 27 nM. UPGL00004 has a strong inhibitory effect on the proliferation of highly aggressive triple negative breast cancer cell lines. purity: 97%
TARGETMOL CHEMICALS INC ALEGLITAZAR 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Aleglitazar (R1439) (R1439) is a potent dual PPAR(alpha)/(gamma) agonist with IC50s of 38 nM and 19 nM for human PPARa and PPAR(gamma) respectively. Aleglitazar can be used for the research of type II diabetes. purity: 99%
Medchemexpress LLC Quizartinib dihydrochloride | 1132827-21-4 | 99.8% | C29H34Cl2N6O4S | 100 MG
Quizartinib dihydrochloride (AC220 dihydrochloride) is the dihydrochloride salt form of Quizartinib. This compound is an orally active, highly selective, and potent second-generation type II FLT3 tyrosine kinase inhibitor, characterized by a Kd of 1.6 nM. It is intended for research use only.
- Highly selective and potent second-generation type II FLT3 tyrosine kinase inhibitor
- Effectively inhibits wild-type FLT3 and FLT3-ITD autophosphorylation
- Can be utilized in PROTAC technology to create FLT3 degraders
- Capable of inducing apoptosis
- Provides high purity for reliable research results
- Presents as a white to off-white solid
TARGETMOL CHEMICALS INC DP-1 HYDROCHLORIDE 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. DP-1 hydrochloride is a degradation product of SDC-TRAP-0063 a fragment of Ganetespib a heat shock protein 90 (HSP90) inhibitor with antitumor activity. purity: 99%