Oxazinanes
Medchemexpress LLC CN128 hydrochloride | 1335282-05-7 | 98.2% | 10 MM 1 ML
CN128 hydrochloride is an orally active and selective iron chelator. It is used for the research of β-thalassemia.
- Orally active and selective iron chelator
- High selectivity for iron(III) over other metals
- Lacks genetic toxicity and is well-tolerated
- Exhibits good oral bioavailability
- Demonstrates good iron scavenging efficacy in rats
- Iron removal efficacies are dose-dependent
Medchemexpress LLC CN128 hydrochloride | 1335282-05-7 | 98.2% | 250 MG
CN128 hydrochloride (CN328) is an orally active and selective iron chelator primarily used in the research of β-thalassemia. It demonstrates high selectivity for iron(III) over other metals and has been shown to lack genetic toxicity.
- Orally active and selective iron chelator
- Used for research of β-thalassemia
- Exhibits high selectivity for iron(III) over other metals
- Lacks genetic toxicity
- Demonstrates good oral bioavailability (82.6%) in rats
- Well-tolerated in rats with no mortality at higher dose levels
- Shows good iron scavenging efficacy in rats
Medchemexpress LLC iMAC2 hydrochloride | 335166-00-2 | 93.98% | 542.11 | 10 MG
iMAC2 hydrochloride is a potent MAC (mitochondrial apoptosis-induced channel) inhibitor, with an IC50 of 28 nM and a LD50 of 15000 nM. It shows an anti-apoptotic effect and blocks cytochrome c release. It is for research use only and not sold to patients.
- Potent MAC (mitochondrial apoptosis-induced channel) inhibitor
- IC50 of 28 nM
- LD50 of 15000 nM
- Shows anti-apoptotic effect
- Blocks cytochrome c release
Medchemexpress LLC VU591 hydrochloride | 1315380-70-1 | 98.9% | 404.76 | 1 ML
VU591 hydrochloride is a potent, selective renal outer medullary potassium channel (ROMK or Kir1.1) inhibitor, with an IC50 of 0.24 μM. It can be used for neurological research with HY-108585A (the equivalent of VU591 hydrochloride).
- Potent, selective renal outer medullary potassium channel (ROMK or Kir1.1) inhibitor
- IC50 of 0.24 μM
- Suitable for neurological research
- Binds serum protein
- High metabolic stability
- Shows antidepressive effect in male ICR mice
Medchemexpress LLC SP3N hydrochloride | 99.84% | 764.34 | 1 MG
SP3N hydrochloride is a specific degrader of the prolyl isomerase (FKBP12). The alkylamine of SP3N hydrochloride is metabolized to a reactive aldehyde (SP3CHO), which recruits the SCFFBXO22 ligase for FKBP12 degradation. SP3N hydrochloride may be used in research for cancer.
- Specific degrader of FKBP12.
- Metabolized to a reactive aldehyde (SP3CHO) which recruits SCFFBXO22 ligase for FKBP12 degradation.
- May be used in research for cancer.
Medchemexpress LLC Flunarizine (dihydrochloride) | 30484-77-6 | 99.9% | 1 ML
Flunarizine dihydrochloride is a potent dual Na+/Ca2+ channel (T-type) blocker and a D2 dopamine receptor antagonist. It exhibits anticonvulsive and antimigraine activity, as well as peripheral vasodilator effects. This product is for research use only, not for sale to patients.
- Potent dual Na+/Ca2+ channel (T-type) blocker
- D2 dopamine receptor antagonist
- Exhibits anticonvulsive and antimigraine activity
- Exhibits peripheral vasodilator effects
- Harmful if swallowed
- Store at 4°C, sealed, away from moisture
- If in solvent, store at -80°C for 6 months or -20°C for 1 month, sealed, away from moisture
Selleck Chemical LLC Pivmecillinam hydrochloride S5473-1g
Pivmecillinam is a -lactam antibiotic and a prodrug of mecillinam It has selective activity against Gram-negative bacteria and is used primarily in the treatment of lower urinary tract infections
Chemscene ChemScene | (4-(Aminomethyl)phenyl)(imino)(methyl)-l6-sulfanone hydrochloride | 250MG | CS-0833572 | 0.97 | 1817776-45-6| | 220.72
ChemScene | (4-(Aminomethyl)phenyl)(imino)(methyl)-l6-sulfanone hydrochloride | 250MG | CS-0833572 | 0.97 | 1817776-45-6| | 220.72
Selleck Chemical LLC PRE-084 hydrochloride
PRE-084 hydrochloride (HCl) is a potent selective sigma-1 receptor ( 1 S1R) agonist with IC50 of 44 nM in the sigma receptor assay
TARGETMOL CHEMICALS INC PROCATEROL HYDROCHLORIDE 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Short-acting (beta)2-adrenergic receptor agonist used to treat asthma. purity: 100%
Apexbio Technology LLC PRE-084 hydrochloride 75136-54-8 10mM (in 1mL DMSO)
PRE-084 hydrochloride (CAS 75136-54-8) is a selective agonist of the sigma-1 receptor ( 1R) demonstrating high affinity and specificity over sigma-2 receptors (Ki values 2 2 nM for 1R 13091 nM for 2R) and negligible activity at PCP and other receptor systems (IC50 100 000 nM) In neuronal cell models expressing mutant huntingtin PRE-084 enhances NF- B pathway activation improving antioxidant responses and cell survival In vivo it reverses cognitive impairment induced by CO or trimethyltin and reduces cough response in guinea pig models highlighting PRE-084 as a relevant tool for neurological and respiratory research
TARGETMOL CHEMICALS INC PAROXETINE 500MG
Also available in 25 mg 50 mg 100 mg and bulk. Please contact Fisher for quotes. Paroxetine is a inhibitor of serotonin uptake that is effective in the treatment of depression. purity: 99%
TARGETMOL CHEMICALS INC CHK1-IN-4 HYDROCHLORIDE 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg and bulk. Please contact Fisher for quotes. CHK1-IN-4 hydrochloride is a potent inhibitor of checkpoint kinase 1 (chk1). CHK1-IN-4 hydrochloride potently inhibits chk1 phosphorylation in the tumor cells. CHK1-IN-4 hydrochloride has anti-tumor activity.
eMolecules Combi-Blocks 1-(9-Fluorenylmethyloxycarbonyl-amino)-36-dioxa-8-octaneamine hydrochloride 5g 439369905 SS-1783 98.000 868599-73-9 MFCD04112696 406.910 C21H27ClN2O4
Combi-Blocks 1-(9-Fluorenylmethyloxycarbonyl-amino)-36-dioxa-8-octaneamine hydrochloride 5g 439369905 SS-1783 98.000 868599-73-9 MFCD04112696 406.910 C21H27ClN2O4
TARGETMOL CHEMICALS INC D-3263 HYDROCHLORIDE 5MG
Also available in 1mg 10mg 25mg 50mg and bulk. Please contact Fisher for quotes. D-3263 hydrochloride (D3263 HCl salt) is enteric-coated orally bioavailable transient receptor potential melatonin member 8 (TRPM8) agonist. purity: 99%