Piperazinoazepines
Medchemexpress LLC Mirtazapine-d3 | 1216678-68-0 | 99.7% | 1 MG
Mirtazapine-d3 is a deuterium labeled Mirtazapine, a potent and orally active noradrenergic and specific serotonergic antidepressant (NaSSA) agent. It functions by blocking 5-HT2 and 5-HT3 receptors. This compound is for research use only and can be utilized as a tracer or an internal standard for quantitative analysis.
- Can be used as a tracer
- Functions as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Inhibits 5-HT2 receptors
- Inhibits 5-HT3 receptors
- Deuterium labeled compound
Medchemexpress LLC Mirtazapine | 85650-52-8 | 99.9% | 1 ML
Mirtazapine is a potent and orally active noradrenergic and specific serotonergic antidepressant (NaSSA) agent. It functions as a 5-HT2, 5-HT3, histamine H1 receptor, and α2-adrenoceptor antagonist. Mirtazapine enhances the release of norepinephrine and 5-HT1A-mediated serotonergic transmission.
- Antagonizes adrenergic α2-autoreceptors and α2-heteroreceptors
- Blocks 5-HT2 and 5-HT3 receptors
- Enhances norepinephrine release
- Enhances 5-HT1A-mediated serotonergic transmission
- Reduces activation-induced release of cytokine/chemokine mediators from human CD14+ monocytes
- Inhibits hepatic macrophage/monocyte activation and decreases pro-inflammatory cytokine and chemokine production
Medchemexpress LLC Mianserin hydrochloride | 21535-47-7 | 99.95% | 500 MG
Mianserin hydrochloride is an orally active H1 receptor antagonist and can activate κ-opioid receptor and octopamine receptor. It can be used for the research of neurological diseases such as depression and epilepsy.
- Solid appearance
- Melting/freezing point >230°C
- Stable under recommended storage conditions
- Increases ERK1/2 and CREB phosphorylation
- Modulates social and exploratory behavior
- Raises electroconvulsive thresholds
Medchemexpress LLC Mirtazapine | 85650-52-8 | 99.9% | 50 MG
Mirtazapine (Org3770) is a potent and orally active noradrenergic and specific serotonergic antidepressant (NaSSA) agent. It acts as a 5-HT2, 5-HT3, histamine H1 receptor, and α2-adrenoceptor antagonist.
- Potent and orally active noradrenergic and specific serotonergic antidepressant.
- Antagonizes adrenergic α2-autoreceptors and α2-heteroreceptors, and blocks 5-HT2 and 5-HT3 receptors.
- Enhances the release of norepinephrine and 5-HT1A-mediated serotonergic transmission.
- Significantly reduces activation-induced release of cytokine/chemokine mediators from human CD14+ monocytes in vitro.
- Inhibits hepatic innate immune networks to attenuate immune-mediated liver injury in mice in vivo.
- Suppresses Con A-induced increases in hepatic ICAM-1 expression, reducing neutrophil recruitment into the liver.
Medchemexpress LLC Mianserin hydrochloride | 21535-47-7 | 99.95% | 50 MG
Mianserin hydrochloride (Org GB 94) is an orally active H1 receptor antagonist known for activating κ-opioid and octopamine receptors. It increases ERK1/2 and CREB phosphorylation and antagonizes full κ-opioid agonist and dynorphin A-induced MAPK phosphorylation. This compound modulates social and exploratory behavior, raises electroconvulsive thresholds, and is utilized in research for neurological conditions like depression and epilepsy.
- Acts as an H1 receptor antagonist
- Activates κ-opioid receptor and octopamine receptor
- Increases ERK1/2 and CREB phosphorylation
- Modulates social and exploratory behavior
- Raises electroconvulsive thresholds
- Used in research for neurological diseases
- Exhibits high affinity for human κ-opioid receptors
- Inhibits cyclic AMP accumulation mediated by histamine H1
Medchemexpress LLC Mianserin | 24219-97-4 | 99.4% | 264.36 g/mol | C18H20N2 | 10 MG
Mianserin is a tetracyclic antidepressant-class research chemical that acts as an H1 histamine receptor inverse agonist. Supplied in measured small quantities for laboratory and analytical use, it is provided for research use only and is not intended for human therapeutic use.
- High purity, typically ≈99.4%.
- Tetracyclic antidepressant scaffold with H1 receptor inverse agonist activity.
- Available in measured milligram quantities suitable for analytical and research applications.
- Molecular formula C18H20N2 and molecular weight 264.36 g/mol.
- Characterized and documented with supporting datasheet, COA, and spectral data for verification.
Medchemexpress LLC Mianserin | 24219-97-4 | 99.42% | 25 MG
Mianserin is an orally active H1 receptor antagonist that can also activate κ-opioid and octopamine receptors. It increases ERK1/2 and CREB phosphorylation and antagonizes full κ-opioid agonist and Dynorphin A-induced MAPK phosphorylation. Mianserin modulates social and exploratory behavior and raises electroconvulsive thresholds. It is used in the research of neurological diseases such as depression and epilepsy.
- Orally active H1 receptor antagonist
- Activates κ-opioid receptor and octopamine receptor
- Increases ERK1/2 and CREB phosphorylation
- Antagonizes full κ-opioid agonist and Dynorphin A-induced MAPK phosphorylation
- Modulates social and exploratory behavior
- Raises electroconvulsive thresholds
- Useful for research into neurological diseases like depression and epilepsy
Selleck Chemical LLC Mianserin HCl S1382-50mg
Mianserin (Bolvidon Norval Tolvon ORG GB-94 HCl Mianserin hydrochloride) is an potent antagonist of H1 histamine receptor and 5-HT serotonin receptors used for the treatment of depression
Medchemexpress LLC Mirtazapine | 85650-52-8 | 99.9% | 25 MG
Mirtazapine is a potent and orally active noradrenergic and specific serotonergic antidepressant (NaSSA) agent. It acts as a 5-HT2, 5-HT3, histamine H1 receptor, and α2-adrenoceptor antagonist, enhancing the release of norepinephrine and 5-HT1A-mediated serotonergic transmission.
- Antagonizes 5-HT2, 5-HT3, histamine H1, and α2-adrenoceptors
- Enhances norepinephrine and 5-HT1A-mediated serotonergic transmission
- Reduces activation-induced release of cytokine/chemokine mediators from human CD14+ monocytes in vitro
- Inhibits Con A-induced liver injury in vivo by suppressing hepatic macrophage/monocyte activation
- Decreases pro-inflammatory cytokine and chemokine production and reduces neutrophil recruitment into the liver in vivo
Selleck Chemical LLC Mirtazapine S2016-50mg
Mirtazapine (Org3770 6-Azamianserin) is an adrenergic and seroton receptor antagonist used to treat depression
Sigma Aldrich Fine Chemicals Biosciences Mirtazapine >=98% (HPLC) | 85650-52-8 | MFCD00865427 | 50MG
Mirtazapine >=98% (HPLC) | Purity: >=98% (HPLC) | Mol Wt: 265.35 | 85650-52-8 | MFCD00865427 | 50MG
Sigma Aldrich Fine Chemicals Biosciences Mirtazapine United States Pharmacopeia (USP) Reference Standard | 85650-52-8 | MFCD00865427 | 350MG
Mirtazapine United States Pharmacopeia (USP) Reference Standard | Mol Wt: 265.35 | 85650-52-8 | MFCD00865427 | 350MG
Medchemexpress LLC Mianserin hydrochloride | 21535-47-7 | 99.95% | 200 MG
Mianserin hydrochloride | 21535-47-7 | 99.95% | 200 MG
Medchemexpress LLC Mirtazapine | 85650-52-8 | MFCD00865427 | 265.36 | C17H19N3 | 10 MG
Mirtazapine analytical reference standard for research and analytical applications, provided as a small-mass powdered material suitable for preparing stock solutions and calibrants. It represents the standard form of mirtazapine used in method development, calibration, and quality control workflows.
- Analytical reference suitable for method development and calibration.
- Used in studies targeting 5-HT, histamine H1, and adrenergic receptors.
- Molecular formula C17H19N3 and molecular weight 265.36 g/mol.
- Available in small mass packs (for example, 1 mg, 5 mg, 10 mg) for stock preparation.
- Storage guidance provided for powder and solutions to preserve stability.