Piperazinoazepines
Mianserin hydrochloride
CAS: 21535-47-7 Molecular Formula: C18H21ClN2 Molecular Weight (g/mol): 300.83 MDL Number: MFCD00055072 InChI Key: YNPFMWCWRVTGKJ-UHFFFAOYNA-N Synonym: mianserin hydrochloride,mianserine hydrochloride,mianserin hcl,athymil,bolvidon,tolvon,tolvin,org gb 94,lerivon PubChem CID: 68551 ChEBI: CHEBI:31843 IUPAC Name: hydrogen 5-methyl-2,5-diazatetracyclo[13.4.0.0²,⁷.0⁸,¹³]nonadeca-1(19),8,10,12,15,17-hexaene chloride SMILES: [H+].[Cl-].CN1CCN2C(C1)C1=CC=CC=C1CC1=CC=CC=C21
Mirtazapine, 98%
CAS: 85650-52-8 Molecular Formula: C17H19N3 Molecular Weight (g/mol): 265.35 InChI Key: RONZAEMNMFQXRA-UHFFFAOYSA-N Synonym: mirtazapine,remeron,mepirzepine,remergil,zispin,remergon,rexer,6-azamianserin,remeron soltab,mepirzapin PubChem CID: 4205 ChEBI: CHEBI:6950 SMILES: CN1CCN2C(C1)C3=CC=CC=C3CC4=C2N=CC=C4
Mianserin Hydrochloride 98.0+%, TCI America™
CAS: 21535-47-7 Molecular Formula: C18H21ClN2 Molecular Weight (g/mol): 300.83 MDL Number: MFCD00055072 InChI Key: YNPFMWCWRVTGKJ-UHFFFAOYNA-N Synonym: mianserin hydrochloride,mianserine hydrochloride,mianserin hcl,athymil,bolvidon,tolvon,tolvin,org gb 94,lerivon PubChem CID: 68551 ChEBI: CHEBI:31843 IUPAC Name: hydrogen 5-methyl-2,5-diazatetracyclo[13.4.0.0²,⁷.0⁸,¹³]nonadeca-1(19),8,10,12,15,17-hexaene chloride SMILES: [H+].[Cl-].CN1CCN2C(C1)C1=CC=CC=C1CC1=CC=CC=C21
Mirtazapine 98.0+%, TCI America™
CAS: 85650-52-8 Molecular Formula: C17H19N3 Molecular Weight (g/mol): 265.36 MDL Number: MFCD00865427 InChI Key: RONZAEMNMFQXRA-UHFFFAOYSA-N Synonym: mirtazapine,remeron,mepirzepine,remergil,zispin,remergon,rexer,6-azamianserin,remeron soltab,mepirzapin PubChem CID: 4205 ChEBI: CHEBI:6950 SMILES: CN1CCN2C(C1)C3=CC=CC=C3CC4=C2N=CC=C4
Medchemexpress LLC Mianserin | 24219-97-4 | 99.4% | 264.36 g/mol | C18H20N2 | 10 MG
Mianserin is a tetracyclic antidepressant-class research chemical that acts as an H1 histamine receptor inverse agonist. Supplied in measured small quantities for laboratory and analytical use, it is provided for research use only and is not intended for human therapeutic use.
- High purity, typically ≈99.4%.
- Tetracyclic antidepressant scaffold with H1 receptor inverse agonist activity.
- Available in measured milligram quantities suitable for analytical and research applications.
- Molecular formula C18H20N2 and molecular weight 264.36 g/mol.
- Characterized and documented with supporting datasheet, COA, and spectral data for verification.
Medchemexpress LLC Mirtazapine | 85650-52-8 | 99.9% | 50 MG
Mirtazapine (Org3770) is a potent and orally active noradrenergic and specific serotonergic antidepressant (NaSSA) agent. It acts as a 5-HT2, 5-HT3, histamine H1 receptor, and α2-adrenoceptor antagonist.
- Potent and orally active noradrenergic and specific serotonergic antidepressant.
- Antagonizes adrenergic α2-autoreceptors and α2-heteroreceptors, and blocks 5-HT2 and 5-HT3 receptors.
- Enhances the release of norepinephrine and 5-HT1A-mediated serotonergic transmission.
- Significantly reduces activation-induced release of cytokine/chemokine mediators from human CD14+ monocytes in vitro.
- Inhibits hepatic innate immune networks to attenuate immune-mediated liver injury in mice in vivo.
- Suppresses Con A-induced increases in hepatic ICAM-1 expression, reducing neutrophil recruitment into the liver.
Medchemexpress LLC Mirtazapine-d3 | 1216678-68-0 | 99.7% | 1 MG
Mirtazapine-d3 is a deuterium labeled Mirtazapine, a potent and orally active noradrenergic and specific serotonergic antidepressant (NaSSA) agent. It functions by blocking 5-HT2 and 5-HT3 receptors. This compound is for research use only and can be utilized as a tracer or an internal standard for quantitative analysis.
- Can be used as a tracer
- Functions as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Inhibits 5-HT2 receptors
- Inhibits 5-HT3 receptors
- Deuterium labeled compound
Medchemexpress LLC Mianserin hydrochloride | 21535-47-7 | 99.95% | 50 MG
Mianserin hydrochloride (Org GB 94) is an orally active H1 receptor antagonist known for activating κ-opioid and octopamine receptors. It increases ERK1/2 and CREB phosphorylation and antagonizes full κ-opioid agonist and dynorphin A-induced MAPK phosphorylation. This compound modulates social and exploratory behavior, raises electroconvulsive thresholds, and is utilized in research for neurological conditions like depression and epilepsy.
- Acts as an H1 receptor antagonist
- Activates κ-opioid receptor and octopamine receptor
- Increases ERK1/2 and CREB phosphorylation
- Modulates social and exploratory behavior
- Raises electroconvulsive thresholds
- Used in research for neurological diseases
- Exhibits high affinity for human κ-opioid receptors
- Inhibits cyclic AMP accumulation mediated by histamine H1
Medchemexpress LLC Mirtazapine-d3 | 1216678-68-0 | MFCD09841051 | 98.6% | 268.38 | C17H16D3N3 | 10 MG
Mirtazapine-d3 is a deuterium-labeled analogue of mirtazapine used as an internal standard and tracer for quantitative analytical methods. It delivers a mass-shifted reference for accurate quantitation in pharmacokinetic, bioanalytical, and metabolite studies, improving precision in LC-MS, GC-MS, and NMR assays.
- Deuterium-labeled internal standard for quantitative analysis.
- Compatible with LC-MS, GC-MS, and NMR techniques.
- High purity for consistent analytical performance.
- Powder form with defined cold-storage stability.
Medchemexpress LLC Mirtazapine | 85650-52-8 | MFCD00865427 | 99.9% | 265.36 | C17H19N3 | 10 MG
Mirtazapine is a tetracyclic antidepressant used in research to probe noradrenergic and specific serotonergic mechanisms. This research-grade 10 mg sample is supplied as a solid for laboratory use and is characterized by its reported high purity and defined molecular properties.
- Potent NaSSA agent for studies of noradrenergic and serotonergic pathways.
- Antagonist of 5-HT2, 5-HT3, H1, and α2 receptors.
- High reported purity (99.9%) suitable for analytical and in vitro assays.
- Molecular formula C17H19N3 and molecular weight 265.36 aid compound identification.
- Primarily metabolized by CYP1A2, CYP2D6, and CYP3A4, relevant for metabolism studies.
Medchemexpress LLC Mianserin hydrochloride | 21535-47-7 | 99.95% | 200 MG
Mianserin hydrochloride | 21535-47-7 | 99.95% | 200 MG
Medchemexpress LLC Mirtazapine | 85650-52-8 | MFCD00865427 | 265.36 | C17H19N3 | 10 MG
Mirtazapine analytical reference standard for research and analytical applications, provided as a small-mass powdered material suitable for preparing stock solutions and calibrants. It represents the standard form of mirtazapine used in method development, calibration, and quality control workflows.
- Analytical reference suitable for method development and calibration.
- Used in studies targeting 5-HT, histamine H1, and adrenergic receptors.
- Molecular formula C17H19N3 and molecular weight 265.36 g/mol.
- Available in small mass packs (for example, 1 mg, 5 mg, 10 mg) for stock preparation.
- Storage guidance provided for powder and solutions to preserve stability.
Medchemexpress LLC Mianserin hydrochloride | 21535-47-7 | 99.95% | 500 MG
Mianserin hydrochloride is an orally active H1 receptor antagonist and can activate κ-opioid receptor and octopamine receptor. It can be used for the research of neurological diseases such as depression and epilepsy.
- Solid appearance
- Melting/freezing point >230°C
- Stable under recommended storage conditions
- Increases ERK1/2 and CREB phosphorylation
- Modulates social and exploratory behavior
- Raises electroconvulsive thresholds