Piperazinoazepines
Mirtazapine, 98%
CAS: 85650-52-8 Molecular Formula: C17H19N3 Molecular Weight (g/mol): 265.35 InChI Key: RONZAEMNMFQXRA-UHFFFAOYSA-N Synonym: mirtazapine,remeron,mepirzepine,remergil,zispin,remergon,rexer,6-azamianserin,remeron soltab,mepirzapin PubChem CID: 4205 ChEBI: CHEBI:6950 SMILES: CN1CCN2C(C1)C3=CC=CC=C3CC4=C2N=CC=C4
Mianserin hydrochloride
CAS: 21535-47-7 Molecular Formula: C18H21ClN2 Molecular Weight (g/mol): 300.83 MDL Number: MFCD00055072 InChI Key: YNPFMWCWRVTGKJ-UHFFFAOYNA-N Synonym: mianserin hydrochloride,mianserine hydrochloride,mianserin hcl,athymil,bolvidon,tolvon,tolvin,org gb 94,lerivon PubChem CID: 68551 ChEBI: CHEBI:31843 IUPAC Name: hydrogen 5-methyl-2,5-diazatetracyclo[13.4.0.0²,⁷.0⁸,¹³]nonadeca-1(19),8,10,12,15,17-hexaene chloride SMILES: [H+].[Cl-].CN1CCN2C(C1)C1=CC=CC=C1CC1=CC=CC=C21
Mirtazapine 98.0+%, TCI America™
CAS: 85650-52-8 Molecular Formula: C17H19N3 Molecular Weight (g/mol): 265.36 MDL Number: MFCD00865427 InChI Key: RONZAEMNMFQXRA-UHFFFAOYSA-N Synonym: mirtazapine,remeron,mepirzepine,remergil,zispin,remergon,rexer,6-azamianserin,remeron soltab,mepirzapin PubChem CID: 4205 ChEBI: CHEBI:6950 SMILES: CN1CCN2C(C1)C3=CC=CC=C3CC4=C2N=CC=C4
Mianserin Hydrochloride 98.0+%, TCI America™
CAS: 21535-47-7 Molecular Formula: C18H21ClN2 Molecular Weight (g/mol): 300.83 MDL Number: MFCD00055072 InChI Key: YNPFMWCWRVTGKJ-UHFFFAOYNA-N Synonym: mianserin hydrochloride,mianserine hydrochloride,mianserin hcl,athymil,bolvidon,tolvon,tolvin,org gb 94,lerivon PubChem CID: 68551 ChEBI: CHEBI:31843 IUPAC Name: hydrogen 5-methyl-2,5-diazatetracyclo[13.4.0.0²,⁷.0⁸,¹³]nonadeca-1(19),8,10,12,15,17-hexaene chloride SMILES: [H+].[Cl-].CN1CCN2C(C1)C1=CC=CC=C1CC1=CC=CC=C21
Sigma Aldrich Fine Chemicals Biosciences Mirtazapine >=98% (HPLC) | 85650-52-8 | MFCD00865427 | 10MG
Mirtazapine >=98% (HPLC) | Purity: >=98% (HPLC) | Mol Wt: 265.35 | 85650-52-8 | MFCD00865427 | 10MG
Sigma Aldrich Fine Chemicals Biosciences Mirtazapine for system suitability European Pharmacopoeia (EP) Reference Standard | 85650-52-8 | MFCD00865427 |
Mirtazapine for system suitability European Pharmacopoeia (EP) Reference Standard | Mol Wt: 265.35 | 85650-52-8 | MFCD00865427 |
Medchemexpress LLC Mianserin | 24219-97-4 | 99.4% | 50 MG
Mianserin is an orally active H1 receptor antagonist that can activate κ-opioid and octopamine receptors. It increases ERK1/2 and CREB phosphorylation, and antagonizes full κ-opioid agonist and Dynorphin A-induced MAPK phosphorylation. It modulates social and exploratory behavior and raises electroconvulsive thresholds. Mianserin is used for research of neurological diseases such as depression and epilepsy.
- Orally active H1 receptor antagonist
- Activates κ-opioid receptor
- Activates octopamine receptor
- Increases ERK1/2 and CREB phosphorylation
- Antagonizes full κ-opioid agonist and Dynorphin A-induced MAPK phosphorylation
- Modulates social and exploratory behavior
- Raises electroconvulsive thresholds
- Useful for research of neurological diseases like depression and epilepsy
Medchemexpress LLC Mianserin | 24219-97-4 | 99.4% | 5 MG
Mianserin (Mianserine) is an orally active H1 receptor antagonist. It can activate κ-opioid receptors and octopamine receptors. Mianserin increases ERK1/2 and CREB phosphorylation and antagonizes full κ-opioid agonist and Dynorphin A-induced MAPK phosphorylation. It modulates social and exploratory behavior and raises electroconvulsive thresholds. It is used in research for neurological diseases such as depression and epilepsy.
- Orally active H1 receptor antagonist
- Activates κ-opioid and octopamine receptors
- Increases ERK1/2 and CREB phosphorylation
- Modulates social and exploratory behavior
- Raises electroconvulsive thresholds
- Used in research for neurological diseases such as depression and epilepsy
Medchemexpress LLC Mirtazapine | 85650-52-8 | MFCD00865427 | 99.95% | 100 MG
Mirtazapine (Standard) is the analytical standard of Mirtazapine, intended for research and analytical applications. It is a potent and orally active noradrenergic and specific serotonergic antidepressant (NaSSA) agent. Mirtazapine is also a 5-HT2, 5-HT3, histamine H1 receptor, and α2-adrenoceptor antagonist with pKi values of 8.05, 8.1, 9.3, and 6.95, respectively.
- Analytical standard for research and analytical applications
- Potent and orally active noradrenergic and specific serotonergic antidepressant (NaSSA) agent
- 5-HT2, 5-HT3, histamine H1 receptor, and α2-adrenoceptor antagonist
- Used in qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS
Medchemexpress LLC Mirtazapine | 85650-52-8 | MFCD00865427 | 99.9% | 25 MG
Mirtazapine is a potent and orally active noradrenergic and specific serotonergic antidepressant (NaSSA) agent. It acts as an antagonist for 5-HT2, 5-HT3, histamine H1 receptors, and α2-adrenoceptors. This compound is intended for research use only and is not sold to patients.
- Potent and orally active NaSSA agent
- Antagonist of multiple receptors: 5-HT2, 5-HT3, histamine H1 receptor, and α2-adrenoceptor
- Enhances norepinephrine and 5-HT1A-mediated serotonergic transmission
- Inhibits hepatic macrophage/monocyte activation, decreases pro-inflammatory cytokine and chemokine production, and suppresses ICAM-1 expression, leading to reduced neutrophil recruitment into the liver (observed in mice)
- Metabolized by CYP1A2, CYP2D6, and CYP3A4 isoenzymes
- Significantly reduces activation-induced release of cytokine/chemokine mediators from human CD14+ monocytes in vitro
Medchemexpress LLC Mirtazapine | 85650-52-8 | 99.9% | 200 MG
Mirtazapine is a potent and orally active noradrenergic and specific serotonergic antidepressant (NaSSA) agent. It acts as a 5-HT2, 5-HT3, histamine H1 receptor, and α2-adrenoceptor antagonist. Its metabolism is primarily handled by cytochrome P450 isoenzymes CYP1A2, CYP2D6, and CYP3A4.
- Acts as a 5-HT2, 5-HT3, histamine H1 receptor, and α2-adrenoceptor antagonist
- Enhances norepinephrine and 5-HT1A-mediated serotonergic transmission
- Significantly reduces activation-induced release of cytokine/chemokine mediators from human CD14+ monocytes
- Inhibits Con A-induced liver injury by suppressing hepatic macrophage/monocyte activation
Medchemexpress LLC Mirtazapine-d3 | 1216678-68-0 | M002686 | 99.68% | 5 MG
Mirtazapine-d3 is a deuterium-labeled Mirtazapine. Mirtazapine is a 5-HT receptor inhibitor, and a potent, orally active noradrenergic and specific serotonergic antidepressant (NaSSA) that works by blocking 5-HT2 and 5-HT3 receptors.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Potent, orally active noradrenergic and specific serotonergic antidepressant (NaSSA)
- Blocks 5-HT2 and 5-HT3 receptors
- Deuterium-labeled compound
Medchemexpress LLC Mirtazapine (Standard) | 85650-52-8 | 99.9% | 5 MG
Mirtazapine (Standard) is the analytical standard of Mirtazapine, intended for research and analytical applications. This potent, orally active noradrenergic and specific serotonergic antidepressant (NaSSA) agent also functions as a 5-HT2, 5-HT3, histamine H1 receptor, and α2-adrenoceptor antagonist. It is commonly used in qualitative, quantitative, and methodological research experiments, including HPLC, GC, and MS.
- Analytical standard for Mirtazapine
- Potent and orally active noradrenergic and specific serotonergic antidepressant (NaSSA)
- Functions as a 5-HT2, 5-HT3, histamine H1 receptor, and α2-adrenoceptor antagonist
- Suitable for research and analytical applications
- Used in HPLC, GC, and MS experiments
- High purity of 99.95%
- White to off-white solid appearance
- Molecular weight of 265.36 and formula C₁₇H₁₉N₃
Medchemexpress LLC (R)-Mirtazapine ((R)-Org3770) | 61364-37-2 | 99.8%
(R)-Mirtazapine is an R(+)-enantiomer of Mirtazapine with antinociceptive properties. It functions as a 5-HT3 receptor antagonist and is primarily metabolized by CYP3A4.
- Acts as a 5-HT3 receptor antagonist
- Primarily metabolized by CYP3A4
- Exhibits antinociceptive properties
- Suitable for research use only