Piperidines

Enzo Life Sciences dBET1 (10mg). CAS: 1799711-21-9

dBET1 is a PROTAC, consisting of a BRD4-ligand JQ-1 linked to a cereblon E3 ligase ligand, targeting on BET bromodomain BRD4. Purity: ≥99%. Long Term Storage: -20°C.

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Medchemexpress LLC Avadomide | HY-100507

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Avadomide

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eMolecules​ 1400744-19-5 | [(3S)-1-methylpiperidin-3-yl]methanamine dihydrochloride | MFCD21641985 | 1g

Medchem Express | BL-1249 | 5mg | 495799677 | HY-108596 | 18200-13-0 | MFCD08276915 | 291.358 | C17H17N5

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eMolecules​ 902135-91-5 | Medchem Express | AT7519 (Hydrochloride) | 5mg | 446271282 | HY-50943 | MFCD14636428 | 418.7 | C16H18Cl3N5O2

Medchem Express | AT7519 (Hydrochloride) | 5mg | 446271282 | HY-50943 | 902135-91-5 | MFCD14636428 | 418.700 | C16H18Cl3N5O2

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Medchemexpress LLC Pomalidomide-amino-PEG4-NH2 (hydrochloride) | 2331259-45-9 | 542.97 | 100 MG

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Pomalidomide-amino-PEG4-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate. It incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology. This compound is designed for use in PROTACs, which contain two different ligands connected by a linker. These PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

• Synthesized E3 ligase ligand-linker conjugate
• Incorporates Pomalidomide based cereblon ligand
• Utilizes PROTAC technology
• Exploits the intracellular ubiquitin-proteasome system
• Selectively degrades target proteins

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Biotium Involucrin(IVRN/827), CF647 conjugate, 0.1mg/mL

This antibody recognizes a protein of 66 kDa-170 kDa, identified as involucrin. In Western blotting of cultured human keratinocytes, this MAb reacts with a 120 kDa protein. Involucrin is expressed in a range of stratified squamous epithelia, including the cornea, which lacks a distinct cornified layer. In normal epidermis, it is first expressed in the upper spinous layers, and in keratinocyte cultures, all cells that have left the basal layer express it. Involucrin expression is altered in pathological conditions: in psoriasis and other benign epidermal hyperplasias, involucrin expression begins closer to the basal layer than normal; expression is abnormal in squamous cell carcinomas and premalignant lesions, and is reduced in severe dysplasias of the larynx and cervix.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like

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Medchemexpress LLC Pomalidomide-amino-PEG4-NH2 hydrochloride | 2331259-45-9 | >99.3% | 542.97 | 50 MG

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Pomalidomide-amino-PEG4-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate. This compound incorporates the Pomalidomide-based cereblon ligand and a linker, commonly utilized in PROTAC technology. PROTACs, or Proteolysis-targeting chimeras, are designed to selectively degrade target proteins by exploiting the intracellular ubiquitin-proteasome system through two distinct ligands connected by a linker: one targeting an E3 ubiquitin ligase and the other targeting the protein of interest.

• Synthesized E3 ligase ligand-linker conjugate
• Incorporates Pomalidomide based cereblon ligand
• Used in PROTAC technology
• Target: E3 ligase ligand-linker conjugates
• Pathway: PROTAC
• Target: Cereblon
• Soluble in DMSO (250 mg/mL)
• Soluble in various in vivo solvent systems (≥ 6.25 mg/mL)

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Medchemexpress LLC HY-10984 50mg Medchemexpress, Pomalidomide CAS:19171-19-8 Purity:>98%

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Medchemexpress, HY-10984 50mg Pomalidomide CAS:19171-19-8 Pomalidomide is the third-generation immunomodulatory agent, functions through interacting with the E3 ligase cereblon and induces degradation of essential Ikaros transcription factors. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

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eMolecules​ 2421217-05-0 | Medchem Express | Pomalidomide-amino-PEG5-NH2 (hydrochloride) | 25mg | 761953696 | HY-133816 | 587.02 | C25H35ClN4O10

ChemScene | Methyl 2-cyano-6-fluorobenzoate | 1g | 559780179 | CS-0099427 | 58332-01-7 | MFCD12911464 | 179.150 | C9H6FNO2

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Aobchem 2-(4-Bromophenyl)-1-(1-piperidinyl)ethanone | ≥95% | CAS 349430-81-5 | C13H16BrNO | 1g

2-(4-Bromophenyl)-1-(1-piperidinyl)ethanone | ≥95% | CAS 349430-81-5 | C13H16BrNO | 1g

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eMolecules​ 72002-30-3 | D-6-Oxo-pipecolinic acid | ChemScene | MFCD09025314 | 143.142 | C6H9NO3 | 98.000 | OC(=O)[C@H]1CCCC(=O)N1 | 250mg | 536805839

D-6-Oxo-pipecolinic acid | ChemScene | 72002-30-3 | MFCD09025314 | 143.142 | C6H9NO3 | 98.000 | OC(=O)[C@H]1CCCC(=O)N1 | 250mg | 536805839

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Accela Chembio Inc Methyl N-boc-piperidine-4-carboxylate | 100g | 124443-68-1 | MFCD02183584 | 97+% | D: 1.07 | Shelf Life: 1800 Days | Light Sensitive/moisture Sensitive/n2

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Methyl N-boc-piperidine-4-carboxylate | 100g | 124443-68-1 | MFCD02183584 | 97+% | D: 1.07 | Shelf Life: 1800 Days | Light Sensitive/moisture Sensitive/n2

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eMolecules​ 912807-35-3 | (R)-Piperidine-3-carboxylic acid tert-butyl ester | J&W PharmLab LLC | MFCD20690120 | 185.267 | C10H19NO2 | 96.000 | CC(C)(C)OC(=O)[C@@H]1CCCNC1 | 1g | 592892569

(R)-Piperidine-3-carboxylic acid tert-butyl ester | J&W PharmLab LLC | 912807-35-3 | MFCD20690120 | 185.267 | C10H19NO2 | 96.000 | CC(C)(C)OC(=O)[C@@H]1CCCNC1 | 1g | 592892569

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Medchemexpress LLC Bms-587101 | 509083-77-6 | 99.4% | 100MG

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Bms-587101 | 509083-77-6 | 99.4% | 100MG

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eMolecules​ 99979-55-2 | 4-OXOPIPERIDINE-2-CARBOXYLIC ACID HCL | AstaTech | MFCD17015054 | 179.600 | C6H10ClNO3 | 95.000 | Cl.OC(=O)C1CC(=O)CCN1 | 1g | 302801154

4-OXOPIPERIDINE-2-CARBOXYLIC ACID HCL | AstaTech | 99979-55-2 | MFCD17015054 | 179.600 | C6H10ClNO3 | 95.000 | Cl.OC(=O)C1CC(=O)CCN1 | 1g | 302801154

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