Piperidines
Medchemexpress LLC A 1120 50mg | 1152782-19-8 | 50MG
A 1120 is a high-affinity nonretinoid retinol-binding protein 4 (RBP4) antagonist with a Ki value of 8 3 nM A 1120 disrupts the interaction between RBP4 and its binding partner transthyretin[1 [2
Medchemexpress LLC Lenalidomide-propargyl-C2-NH2 hydrochloride | 2489242-23-9 | 98.0% | C18H20ClN3O3 | 10MG
Lenalidomide-propargyl-C2-NH2 hydrochloride is a lenalidomide-derived cereblon (CRBN) ligand provided as the hydrochloride salt and intended as a building block for targeted protein degradation research and click-chemistry conjugation in PROTAC development.
- Lenalidomide-derived CRBN ligand for E3 ligase recruitment.
- Contains a propargyl (alkyne) handle for click chemistry conjugation.
- Supplied as the hydrochloride salt for improved handling and stability.
- High purity (98.0%).
- Chemical formula C18H20ClN3O3; molecular weight 361.82.
- Suitable for chemical biology and PROTAC design applications.
eMolecules METHYL N-BOC-3-OXOPIPERIDINE-4-CARBOXYLATE | 220223-46-1 | MFCD12198882 | 1g
WuXi ChemSupply | METHYL N-BOC-3-OXOPIPERIDINE-4-CARBOXYLATE | 1g | 599167391 | LN01274016 | 95.000 | 220223-46-1 | MFCD12198882 | 257.286 | C12H19NO5
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eMolecules AstaTech / ETHYL 4-AMINO-2-HYDROXYPYRIMIDINE-5-CARBOXYLATE / 0.25g / 302808563 / H10232 / 95.000 / 20187-46-6 / MFCD00014603 / 183.167 / C7H9N3O3
AstaTech / ETHYL 4-AMINO-2-HYDROXYPYRIMIDINE-5-CARBOXYLATE / 0.25g / 302808563 / H10232 / 95.000 / 20187-46-6 / MFCD00014603 / 183.167 / C7H9N3O3
Apexbio Technology LLC Amodiaquine dihydrochloride dihydrate 6398-98-7 500mg
Amodiaquine dihydrochloride dihydrate (CAS 6398-98-7) is a small-molecule inhibitor targeting histamine N-methyltransferase (HNMT) It is designed to inhibit HNMT thereby affecting intracellular histamine metabolism Amodiaquine dihydrochloride dihydrate exerts its biological activity primarily through inhibition of HNMT In biochemical assays involving rat kidney-derived HNMT amodiaquine demonstrates inhibitory activity with a reported Ki value of approximately 18 6 nM Based on these pharmacological properties amodiaquine dihydrochloride dihydrate holds research potential in investigating histamine metabolism pathways in inflammatory disease models
Apexbio Technology LLC Flupenthixol dihydrochloride 2413-38-9 5mg
Flupenthixol dihydrochloride (CAS 2413-38-9) is a thioxanthene-derived small molecule primarily developed as an antipsychotic agent It functions as a dopamine D2 receptor antagonist modulating dopaminergic neurotransmission in the central nervous system In vitro assays demonstrate minimum inhibitory concentrations (MICs) of 10 100 g/mL against most bacterial strains with inhibitory effects observed at lower concentrations for select species including Staphylococcus aureus and Vibrio cholerae In vivo studies show that flupenthixol significantly reduces bacterial load and increases survival in murine infection models Clinically it has been evaluated for the management of schizophrenia and mood disorders supporting its utility in neuropharmacological and antimicrobial research
Medchemexpress LLC GSK2879552 dihydrochloride | 1902123-72-1 | MFCD30481342 | 99.8% | 437.4 g·mol⁻1 | C23H30Cl2N2O2 | 10 MG
GSK2879552 dihydrochloride is the dihydrochloride salt of an orally bioavailable, selective, mechanism-based irreversible inhibitor of lysine-specific demethylase 1 (LSD1/KDM1A). It is used as a research reagent in epigenetic and oncology studies and has been evaluated in early clinical trials for hematologic and solid tumor indications.
- Dihydrochloride salt form for improved solubility.
- Irreversible LSD1 inhibitor (mechanism-based inactivator).
- Orally bioavailable scaffold used in preclinical and clinical research.
- High purity (≈99.8%) suitable for research applications.
- Available in multiple solid and solution formats and milligram quantities.