Pyridazines and derivatives
Medchemexpress LLC 3-pyridin-3-ylpropyl (2S)-1-(3,3-dimethyl-2-oxopentanoyl)pyrrolidine-2-carboxylate | 186452-09-5 | MFCD00953146 | 99.8% | 360.45 g/mol | C20H28N2O4 | 10MM 1ML
GPI-1046 is a non-immunosuppressive immunophilin ligand used in preclinical research for neuroprotection and modulation of glutamate transport. It is supplied in solution and solid formats for flexible use in in vitro and in vivo studies, and is intended for research use only.
- Non-immunosuppressive immunophilin ligand with reported neuroprotective activity.
- Modulates glutamate transporter 1 (GLT1) in preclinical models.
- Available as a 10 mM solution in DMSO and as solid mg quantities for experimental flexibility.
- High purity (≈99.8%).
- Molecular weight 360.45 g/mol; formula C20H28N2O4 for reference.
- Recommended storage: protect from light; in solvent store at -80°C for long-term preservation.
Medchemexpress LLC Phthalazine | 253-52-1 | 130.15 | 1 ML
Phthalazine is a substrate for human aldehyde oxidase 1, which can lead to the production of reactive oxygen species (ROS) and subsequent enzyme inactivation. It is a nitrogen-containing organic heterocyclic compound. Phthalazine has demonstrated antitumor activity in various cancers including blood cancer, breast cancer, colon cancer, lung cancer, and renal cancer.
- Substrate for human aldehyde oxidase 1
- Leads to the production of reactive oxygen species (ROS)
- Nitrogen-containing organic heterocyclic compound
- Demonstrated antitumor activity in various cancers
Medchemexpress LLC 3-pyridin-3-ylpropyl (2S)-1-(3,3-dimethyl-2-oxopentanoyl)pyrrolidine-2-carboxylate | 186452-09-5 | MFCD00953146 | 99.8% | 360.4 g/mol | C20H28N2O4 | 50MG
GPI-1046 is a small-molecule immunophilin ligand reported to have neuroprotective effects and to modulate glutamate transporter activity. It is supplied in small laboratory pack sizes, typically as a DMSO solution, for preclinical research use only.
- Chemical formula C20H28N2O4.
- Molecular weight 360.4 g/mol.
- CAS number 186452-09-5.
- Purity 99.8%.
- Available as solution in DMSO and multiple small pack sizes.
- Intended for preclinical research use only.
Medchemexpress LLC MC 1046 (Impurity A of Calcipotriol) | 126860-83-1 | C27H38O3 | 500 UG
MC 1046 is an impurity of Calcipotriol, a Vitamin D3 analog and ligand of VDR-like receptors. Calcipotriol exhibits minimal effects on calcium homeostasis and regulates cell differentiation and proliferation. It also demonstrates antiproliferative activity against various human cancer cell lines, including HL-60, HL60/MX2, MCF-7, T47D, SCC-25, and mouse WEHI-3 cancer cell lines.
- Impurity of Calcipotriol
- Calcipotriol is a Vitamin D3 analog
- Calcipotriol functions as a ligand of VDR-like receptors
- Exhibits minimal effects on calcium homeostasis
- Regulates cell differentiation and proliferation
- Demonstrates antiproliferative activity against various human cancer cell lines
Cayman Chemical Phthalazinone pyrazole, Purity: ≥98%, CAS: 880487-62-7, 10 mg
A potent inhibitor of Aurora A kinase (IC50 = 31 nM); does not inhibit Aurora B kinase at doses up to 100 μM; inhibits the proliferation of HCT116, COLO 205, and MCF-7 cells (IC50 = 7.8, 2.9, and 1.6 μM, respectively)
Aobchem 2-Chloro-1-(3-isopropylphenyl)ethanone | 97% | CAS 1824050-46-5 | C11H13ClO | 250mg
2-Chloro-1-(3-isopropylphenyl)ethanone | 97% | CAS 1824050-46-5 | C11H13ClO | 250mg
Aobchem (4-Chloro-3-isopropylphenyl)(methyl)sulfane | ≥95% | CAS 2734779-65-6 | C10H13ClS | 250mg
(4-Chloro-3-isopropylphenyl)(methyl)sulfane | ≥95% | CAS 2734779-65-6 | C10H13ClS | 250mg
Accela Chembio Inc 6-methyl-3(2h)-pyridazinone | 25g | 13327-27-0 | MFCD00039720 | 97+% | Shelf Life: 1260 Days | Regular
6-methyl-3(2h)-pyridazinone | 25g | 13327-27-0 | MFCD00039720 | 97+% | Shelf Life: 1260 Days | Regular
Aobchem (4-Bromo-3-isopropylphenyl)(cyclopropyl)methanol | 95% | C13H17BrO | 1g
(4-Bromo-3-isopropylphenyl)(cyclopropyl)methanol | 95% | C13H17BrO | 1g
Aobchem 1-(3-Isopropylphenyl)cyclopentanol | 95% | CAS 1996988-36-3 | C14H20O | 500mg
1-(3-Isopropylphenyl)cyclopentanol | 95% | CAS 1996988-36-3 | C14H20O | 500mg
Aobchem 1-(5 6-Dichloro-3-pyridinyl)-2-methyl-1-propanone | 95% | CAS 1240248-34-3 | C9H9Cl2NO | 250mg
1-(5 6-Dichloro-3-pyridinyl)-2-methyl-1-propanone | 95% | CAS 1240248-34-3 | C9H9Cl2NO | 250mg
Aobchem 2-Fluoro-1-(2-isopropylphenyl)ethanone | 95% | CAS 1973478-48-6 | C11H13FO | 1g
2-Fluoro-1-(2-isopropylphenyl)ethanone | 95% | CAS 1973478-48-6 | C11H13FO | 1g
Aobchem 2-(3-Bromo-5-isopropylphenyl)-6-butyl-1 3 6 2-dioxazaborocane | 95% | C17H27BBrNO2 | 250mg
2-(3-Bromo-5-isopropylphenyl)-6-butyl-1 3 6 2-dioxazaborocane | 95% | C17H27BBrNO2 | 250mg
Aobchem 4-(3 3-Dimethyl-1-oxobutyl)benzonitrile | 95% | CAS 898764-23-3 | C13H15NO | 1g
4-(3 3-Dimethyl-1-oxobutyl)benzonitrile | 95% | CAS 898764-23-3 | C13H15NO | 1g