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Pyridazines and derivatives

Aromatic organic compounds consist of an aromatic six-membered ring containing two adjacent nitrogen atoms and four carbon atoms; includes compounds derived from pyridazines.

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1

eMolecules​ C-(2-Trifluoromethyl-2H-pyrazol-3-yl)-methylamine | 2416146-09-1 | | 1g

J & W PharmLab LLC | C-(2-Trifluoromethyl-2H-pyrazol-3-yl)-methylamine | 1g | 517669409 | 68R0660 | 96.000 | 2416146-09-1 | | 165.119 | C5H6F3N3

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2

Medchemexpress LLC 3-pyridin-3-ylpropyl (2S)-1-(3,3-dimethyl-2-oxopentanoyl)pyrrolidine-2-carboxylate | 186452-09-5 | MFCD00953146 | 99.8% | 360.4 g/mol | C20H28N2O4 | 50MG
SDP

GPI-1046 is a small-molecule immunophilin ligand reported to have neuroprotective effects and to modulate glutamate transporter activity. It is supplied in small laboratory pack sizes, typically as a DMSO solution, for preclinical research use only.

  • Chemical formula C20H28N2O4.
  • Molecular weight 360.4 g/mol.
  • CAS number 186452-09-5.
  • Purity 99.8%.
  • Available as solution in DMSO and multiple small pack sizes.
  • Intended for preclinical research use only.

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3

Medchemexpress LLC 3-pyridin-3-ylpropyl (2S)-1-(3,3-dimethyl-2-oxopentanoyl)pyrrolidine-2-carboxylate | 186452-09-5 | MFCD00953146 | 99.8% | 360.45 g/mol | C20H28N2O4 | 25MG
SDP

GPI-1046 is an orally active, non-immunosuppressive immunophilin ligand with reported neuroprotective properties. It has been shown to reduce ethanol intake by upregulating the glutamate transporter GLT1 and to improve HIV-associated sensory neuropathy by attenuating store-operated calcium (SOC) entry. The compound is provided as a high-purity research chemical in solid and ready-to-use DMSO formulations for preclinical pharmacology studies.

  • Has neuroprotective activity demonstrated in preclinical studies.
  • Upregulates the glutamate transporter GLT1 in relevant brain regions.
  • Attenuates store-operated calcium entry implicated in neuropathy.
  • Provided at high reported purity for research applications.
  • Available as solid packs and DMSO solutions for dosing flexibility.

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4

Medchemexpress LLC 3-pyridin-3-ylpropyl (2S)-1-(3,3-dimethyl-2-oxopentanoyl)pyrrolidine-2-carboxylate | 186452-09-5 | MFCD00953146 | 99.8% | 360.45 g/mol | C20H28N2O4 | 10MM 1ML
SDP

GPI-1046 is a non-immunosuppressive immunophilin ligand used in preclinical research for neuroprotection and modulation of glutamate transport. It is supplied in solution and solid formats for flexible use in in vitro and in vivo studies, and is intended for research use only.

  • Non-immunosuppressive immunophilin ligand with reported neuroprotective activity.
  • Modulates glutamate transporter 1 (GLT1) in preclinical models.
  • Available as a 10 mM solution in DMSO and as solid mg quantities for experimental flexibility.
  • High purity (≈99.8%).
  • Molecular weight 360.45 g/mol; formula C20H28N2O4 for reference.
  • Recommended storage: protect from light; in solvent store at -80°C for long-term preservation.

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