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Filtered Search Results
Sigma Aldrich Fine Chemicals Biosciences Zaprinast solid | 37762-06-4 | MFCD00214073 | 25MG
Zaprinast solid | Mol Wt: 271.27 | 37762-06-4 | MFCD00214073 | 25MG
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Medchemexpress LLC HY-101420 5mg Medchemexpress, VUF10460 CAS:1028327-66-3 Purity:>98%
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Medchemexpress, HY-101420 5mg VUF10460 CAS:1028327-66-3 VUF10460 is a non-imidazole histamine H4 receptor agonist; binds to rat H4 receptor with a pK i of 7.46. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Aobchem 5-(4-Methylphenyl)-2-pyrimidinamine | ≥97% | CAS 31408-17-0 | C11H11N3 | 5g
5-(4-Methylphenyl)-2-pyrimidinamine | ≥97% | CAS 31408-17-0 | C11H11N3 | 5g
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Medchemexpress LLC PKI(5-24) | 99534-03-9 | 99.99% | 2222.38 | 10 MG
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PKI(5-24) is a potent, competitive, and synthetic peptide inhibitor of PKA (cAMP-dependent protein kinase), with a Ki of 2.3 nM. It corresponds to residues 5-24 in the naturally occurring heat-stable protein kinase inhibitor. This 20-residue peptide inhibits phosphotransferase activity of the mutant cGMP kinase with higher potency (Ki of 42 μM) than that of the wild type (Ki of 160 μM). This product is for research use only.
- Potent, competitive, and synthetic peptide inhibitor of PKA (cAMP-dependent protein kinase)
- Ki of 2.3 nM
- Corresponds to residues 5-24 in the naturally occurring heat-stable protein kinase inhibitor
- 20-residue peptide synthesized to correspond to the active site of the skeletal muscle inhibitor protein
- Inhibits phosphotransferase activity of the mutant cGMP kinase with higher potency
- For research use only
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Medchemexpress LLC Pki 14-22 amide,myristoylated | 201422-03-9 | 99.65% | 1209.49 | 5 MG
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Pki 14-22 amide,myristoylated | 201422-03-9 | 99.65% | 1209.49 | 5 MG
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Medchemexpress LLC HY-10115A 100mg , PI-103 (Hydrochloride) CAS:371935-79-4 Purity:98%
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Medchemexpress, HY-10115A 100mg PI-103 (Hydrochloride) CAS:371935-79-4 Formula:C19H17ClN4O3 IC50: 8 nM (p110α), 88 nM (p110β), 48 nM (p110δ), 150 nM (p110γ), 2 nM (DNA-PK), 20 nM (mTORC1), 83 nM (mTORC2), 26 nM (PI3KC2β), 850 nM (ATR), 920 nM (ATM), ~1 μM (PI3KC2α), 2.3 μM (hsVPS34), ~50 μM (PI4KIIIβ) Purity:98% PI-103 Hydrochloride is a potent PI3K and mTOR inhibitor with IC 50 s of 8 nM, 88 nM, 48 nM, 150 nM, 20 nM, and 83 nM for p110α , p110β , p110δ , p110γ , mTORC1 , and mTORC2 . PI-103 also inhibits DNA-PK with an IC50 of 2 nM. Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC Derenofylline | 251945-92-3 | 99.9% | 308.38 | 50 MG
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Derenofylline (SLV 320) is a potent, selective, and orally active adenosine A1 receptor antagonist. It exhibits Ki values of 1 nM for human A1, 200 nM for A3, and 398 nM for A2A receptors. This compound suppresses cardiac fibrosis and attenuates albuminuria without affecting blood pressure in rats. It has also shown to inhibit TGF-β1-induced myofibroblast transformation in vitro and reduce myocardial fibrosis in vivo.
- Potent, selective, and orally active adenosine A1 receptor antagonist
- Suppresses cardiac fibrosis
- Attenuates albuminuria
- Inhibits TGF-β1-induced myofibroblast transformation (in vitro)
- Reduces myocardial fibrosis in 5/6 nephrectomy rats (in vivo)
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Medchemexpress LLC HY-10182 100mg , CHIR-99021 CT99021 CAS:252917-06-9 Purity:98%
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Medchemexpress, HY-10182 100mg CHIR-99021 CT99021 CAS:252917-06-9 Formula:C22H18Cl2N8 IC50: 10 nM/6.7 nM (GSK-3α/β) Purity:98% CHIR-99021 is a GSK-3α/β inhibitor with IC 50 of 10 nM/6.7 nM; > 500-fold selectivity for GSK-3 versus its closest homologs CDC2 and ERK2, as well as other protein kinases. Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Apexbio Technology LLC BAY 61-3606 732983-37-8 5mg
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BAY 61-3606 (CAS 732983-37-8) is a selective orally bioavailable inhibitor of spleen tyrosine kinase (SYK) displaying an IC50 of 10 nM and a Ki of 7 5 nM for SYK by competitively binding ATP This compound shows minimal activity against other tyrosine kinases such as Src Fyn Lyn Btk and Itk at concentrations up to 4 7 M BAY 61-3606 suppresses Fc RI-mediated degranulation and mediator release in mast cells and basophils as well as Fc R-driven responses in macrophages and neutrophils In preclinical models BAY 61-3606 attenuates inflammatory cell functions and reduces allergic and asthmatic responses supporting its utility in investigating SYK-mediated signaling and inflammation
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Aobchem 3-Bromo-6-chloro-2-methylaniline | ≥95% | CAS 1007226-77-8 | C7H7BrClN | 5g
3-Bromo-6-chloro-2-methylaniline | ≥95% | CAS 1007226-77-8 | C7H7BrClN | 5g
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Aobchem 5-Bromo-3-fluoro-2-methylaniline | ≥97% | CAS 886761-86-0 | C7H7BrFN | 1g
5-Bromo-3-fluoro-2-methylaniline | ≥97% | CAS 886761-86-0 | C7H7BrFN | 1g
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Medchemexpress LLC 2-amino-4-(4-pyridyl)-thiazole | 30235-28-0 | 98.9% | 177.23 | C8H7N3S | 1 G
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2-amino-4-(4-pyridyl)-thiazole is a synthetic intermediate used in pharmaceutical and medicinal chemistry research. It is supplied for research use; purity, batch, and storage details are provided on the certificate of analysis.
- Synthetic intermediate for medicinal chemistry and pharmaceutical synthesis.
- Molecular formula: C8H7N3S.
- Molecular weight: 177.23 g/mol.
- High purity reported by HPLC (98.9%).
- Storage: 4°C, protect from light; in solvent: -80°C (6 months), -20°C (1 month).
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eMolecules 68181-17-9 | N-Succinimidyl 3-(2-Pyridyldithio)propionate | Combi-Blocks | MFCD00009636 | 312.360 | C12H12N2O4S2 | 96.000 | O=C(CCSSc1ccccn1)ON1C(=O)CCC1=O | 1g | 415501514
N-Succinimidyl 3-(2-Pyridyldithio)propionate | Combi-Blocks | 68181-17-9 | MFCD00009636 | 312.360 | C12H12N2O4S2 | 96.000 | O=C(CCSSc1ccccn1)ON1C(=O)CCC1=O | 1g | 415501514
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Aobchem 4-Bromo-5-chloro-2-methylaniline | ≥97% | CAS 30273-47-3 | C7H7BrClN | 25g
4-Bromo-5-chloro-2-methylaniline | ≥97% | CAS 30273-47-3 | C7H7BrClN | 25g
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Aobchem AOBCHEM
5001058297 2-BROMO-4-FLUORO-6-METHYLANILI
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