Pyrroles
Medchemexpress LLC Quiflapon (MK-591) | 136668-42-3 | 99.4% | 587.2 g/mol | C34H35ClN2O3S | 100 MG
Quiflapon (MK-591) is a selective and specific 5-lipoxygenase-activating protein (FLAP) inhibitor used in research to study leukotriene biosynthesis and FLAP-mediated pathways. It demonstrates high potency (IC50 = 1.6 nM in a FLAP binding assay) and is supplied as a high-purity analytical standard for assay development and in vitro studies.
- Selective FLAP inhibition with IC50 = 1.6 nM.
- High purity (99.44%) suitable for analytical use.
- Available in multiple formats, including 10 mM solution and 5 mg-100 mg solid quantities.
- Intended for research and assay development applications.
Medchemexpress LLC JNJ-42253432 | 1428327-35-8 | MFCD34676648 | 98.2% | 446.63 g·mol⁻¹ | C28H38N4O | 10MG
JNJ-42253432 is a CNS-penetrant, high-affinity, orally active antagonist of the P2X7 receptor used in preclinical pharmacology to probe P2X7-mediated signaling and receptor occupancy in the central nervous system.
- CNS-penetrant P2X7 receptor antagonist
- High affinity: rat pKi 9.1, human pKi 7.9
- Oral activity demonstrated in preclinical models
- Soluble in DMSO (reported 100 mg/mL) and usable in in-vivo co-solvent formulations
- Reported purity 98.15%
- Molecular weight 446.63 g·mol⁻¹; formula C28H38N4O
- Storage recommendations: powder -20°C long term; in solution -80°C recommended
Apexbio Technology LLC AHU-377 hemicalcium salt 1369773-39-6 10mM (in 1mL DMSO)
AHU-377 hemicalcium salt (CAS 1369773-39-6) is a hemicalcium salt form of AHU-377 a potent inhibitor of neprilysin (neutral endopeptidase) with an IC50 of 5 nM As a prodrug AHU-377 is enzymatically converted to its active metabolite LBQ657 following ester cleavage AHU-377 is a key component of LCZ696 co-formulated with valsartan at a 1 1 molar ratio functioning as an angiotensin receptor neprilysin inhibitor (ARNI) In vivo studies demonstrate that oral administration of AHU-377 induces dose-dependent blood pressure reduction in DAHI-SS rats though it has less pronounced effects in DOCA-salt hypertensive models AHU-377 is widely studied in cardiovascular research particularly in the context of heart failure and hypertension
Medchemexpress LLC HY-50686 500mg , Tivantinib ARQ 197 CAS:905854-02-6 Purity:98%
Medchemexpress, HY-50686 500mg Tivantinib ARQ 197 CAS:905854-02-6 Formula:C23H19N3O2 Ki: 355 nM (c-Met) Purity:98% Tivantinib is a novel and highly selective c-Met tyrosine kinase inhibitor with K i of 355 nM. Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Selleck Chemical LLC Pyrrole-2-carboxylic acid
Pyrrole-2-carboxylic acid (2-Pyrrolecarboxylic acid) is a degradation product of sialic acids and a derivative of the oxidation of the D-hydroxyproline isomers by mammalian D-amino acid oxidase
eMolecules Synthonix / methyl 4-chloro-5-fluoropyridine-3-carboxylate / 50mg / 794074901 / AC80471 / / 1454913-72-4 / MFCD20925650 / 189.570 / C7H5ClFNO2
Synthonix / methyl 4-chloro-5-fluoropyridine-3-carboxylate / 50mg / 794074901 / AC80471 / / 1454913-72-4 / MFCD20925650 / 189.570 / C7H5ClFNO2
Medchemexpress LLC HY-U00070 1mg Medchemexpress, Dirlotapide CAS:481658-94-0 Purity:>98%
Medchemexpress, HY-U00070 1mg Dirlotapide CAS:481658-94-0 Dirlotapide (CP742033) is a gut-selective inhibitor of microsomal triglyceride transfer protein (MTP) that reliably produces weight loss in obese dogs. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
eMolecules Medchem Express / (R)-Ketorolac / 5mg / 482204529 / HY-B0580B / / 66635-93-6 / MFCD00871492 / 255.273 / C15H13NO3
Medchem Express / (R)-Ketorolac / 5mg / 482204529 / HY-B0580B / / 66635-93-6 / MFCD00871492 / 255.273 / C15H13NO3
eMolecules Medchem Express / LLY-507 / 5mg / 446269670 / HY-19313 / / 1793053-37-8 / MFCD28902312 / 574.773 / C36H42N6O
Medchem Express / LLY-507 / 5mg / 446269670 / HY-19313 / / 1793053-37-8 / MFCD28902312 / 574.773 / C36H42N6O
Medchemexpress LLC HY-106150B 5mg Medchemexpress, Eniporide hydrochloride CAS:211813-86-4 Purity:>98%
Medchemexpress, HY-106150B 5mg Eniporide HCl CAS:211813-86-4 Eniporide hydrochloride (EMD-96785 hydrochloride) is a potent Na+/H+ exchange inhibitor. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.