Pyrroles
Medchemexpress LLC (S)-bromoenol lactone | 478288-94-7 | 99.1% | 1 MG
(S)-Bromoenol lactone is a chiral, mechanism-based irreversible inhibitor of calcium-independent phospholipase A2β (iPLA2β) used in biochemical and cellular research to investigate arachidonate release pathways. The compound is supplied at high purity as a solution and is typically stored at -20°C for long-term stability.
- Irreversible inhibitor of calcium-independent phospholipase A2β (iPLA2β)
- Reported activity: IC50 ≈ 2 μM for vasopressin-induced arachidonate release in A10 cells
- Molecular weight 317.18 g/mol; formula C16H13BrO2
- Purity 99.1%
- Storage: solution at -20°C; stable for about 2 years
Medchemexpress LLC Atorvastatin hemicalcium salt | 134523-03-8 | 99.9% | 577.67 | 5 MG
Atorvastatin hemicalcium salt | 134523-03-8 | 99.9% | 577.67 | 5 MG
Selleck Chemical LLC Sacubitril hemicalcium salt S4426-1g
Sacubitril (AHU-377) hemicalcium salt a component of the heart failure medicine LCZ696 is a potent inhibitor of neprilysin (neutral endopeptidase NEP)
Medchemexpress LLC Massoia lactone | 54814-64-1 | 5 G
Massoia lactone is a coconut and creamy fragrant compound primarily isolated from *Cryptocarya massoy*. It is also a fragrant biosurfactant produced by the fungus *Aureobasidium pullulans*.
- Purity: 98.75%
- Molecular weight: 168.23
- Molecular formula: C10H16O2
- Appearance: Liquid
- Color: Light yellow to light brown
- Shipping: Room temperature in continental US (may vary elsewhere)
- Storage (pure form): -20°C for 3 years
- Storage (in solvent): -80°C for 6 months, -20°C for 1 month
- Solubility in DMSO: 200 mg/mL (requires ultrasonic)
- For research use only
Medchemexpress LLC Atorvastatin calcium salt trihydrate | 344423-98-9 | 99.8% | 605.71 | 1 G
Atorvastatin calcium salt trihydrate is a drug belonging to the statin class of drugs used to lower blood cholesterol levels. Atorvastatin calcium salt trihydrate has unique chemical properties that make it an effective tool in controlling high levels of low-density lipoprotein (LDL) cholesterol and triglycerides in the body, reducing the risk of heart attack and stroke. Atorvastatin calcium salt trihydrate works by inhibiting HMG-CoA reductase, the enzyme responsible for producing cholesterol in the liver.
- Lowers blood cholesterol levels.
- Controls high levels of low-density lipoprotein (LDL) cholesterol and triglycerides.
- Reduces the risk of heart attack and stroke.
- Works by inhibiting HMG-CoA reductase, the enzyme responsible for producing cholesterol in the liver.
- Can be used as a biochemical reagent for life science-related research.
Medchemexpress LLC PHA-767491 hydrochloride | 942425-68-5 | MFCD11519962 | 99.5% | 249.70 | C12H12ClN3O | 5 MG
PHA-767491 hydrochloride is a small-molecule research inhibitor that selectively targets Cdc7 and Cdk9 kinases. It is used in biochemical and cellular studies to probe DNA replication initiation, transcriptional regulation, and cancer cell proliferation. The compound exhibits low-nanomolar biochemical potency and measurable cellular activity, and is supplied as a high-purity solid for laboratory research.
- Potent dual Cdc7/Cdk9 inhibition with low-nanomolar IC50 values.
- Demonstrated cellular antiproliferative activity in multiple cancer cell lines.
- High purity suitable for biochemical and cellular assays.
- Solid, light yellow to yellow appearance for convenient handling.
- Stable under recommended storage conditions for research use.
- Analytical documentation available, including datasheet, COA, and SDS.
Cayman Chemical NhexanoylDLHomoserine lactone
A bacterial quorum sensing signaling molecule; produced by mammalian pathogenic and rhizosphere-colonizing bacteria; application to tomato leaves suppresses the development of lesions induced by the plant pathogenic fungi B. cinerea at 60 µM; increases root length and shoot diameter when applied to A. thaliana seedlings in a hydroponic growth system at 10 µM
Cayman Chemical N-desethyl SunItInIb 500ug
An active metabolite of sunitinib; formed when sunitinib undergoes N-de-ethylation by CYP3A4; is pharmacologically active having similar inhibitory activity to sunitinib
Apexbio Technology LLC Bromoenol lactone 88070-98-8 5mg
Bromoenol lactone (CAS 88070-98-8) is an irreversible inhibitor of cytosolic calcium-independent phospholipase A2 (iPLA2) an enzyme involved in the regulation of arachidonic acid release and lysophospholipid production iPLA2 activity is associated with phospholipid remodeling and the generation of signaling molecules that modulate processes such as eicosanoid synthesis insulin secretion apoptosis and cellular proliferation In cellular assays bromoenol lactone induces apoptosis in various cell lines and promotes proteolysis of procaspase-9 and procaspase-3 It also inhibits phosphatidic acid phosphohydrolase activity and disrupts triacylglycerol biosynthesis in macrophage models Bromoenol lactone is widely utilized in studies investigating lipid signaling cell death mechanisms and metabolic pathways
Medchemexpress LLC Atorvastatin calcium hydrate | 344423-98-9 | 99.8% | 605.71 | 250 MG
Atorvastatin calcium hydrate is a statin-class drug designed to lower blood cholesterol and triglyceride levels. It functions by inhibiting HMG-CoA reductase, an enzyme crucial for cholesterol production in the liver. This action helps reduce the risk of heart attack and stroke. It is intended for life science research applications.
- Lowers blood cholesterol levels
- Controls high levels of LDL cholesterol and triglycerides
- Reduces risk of heart attack and stroke
- Inhibits HMG-CoA reductase, an enzyme in the liver
- Intended for life science research
Medchemexpress LLC Pipemidic acid trihydrate | 72571-82-5 | 98.0% | 357.36 | 25 MG
Pipemidic acid trihydrate, a derivative of Piromidic acid, is an antibacterial agent. It inhibits DNA gyrase and is active against gram-negative bacteria, including Pseudomonas aeruginosa, as well as some gram-positive bacteria. It can be used for the research of intestinal, urinary, and biliary tract infections.
- Derivative of piromidic acid
- Antibacterial agent
- Inhibits DNA gyrase
- Active against gram-negative bacteria including Pseudomonas aeruginosa as well as some gram-positive bacteria
- Can be used for the research of intestinal, urinary, and biliary tract infections
Medchemexpress LLC (-)-Corey lactone diol | 32233-40-2 | 172.18 | 1 G
(-)-Corey lactone diol is the reduced form of Corey aldehyde. It serves as a drug intermediate in the synthesis of Beraprost. This product is intended for research use only and is not sold to patients. It appears as a white to off-white solid.
- Reduced form of Corey aldehyde.
- Used as a drug intermediate for the synthesis of Beraprost.
- Exclusively for research purposes.
- Appears as a white to off-white solid.
- Powder storage: -20°C for 3 years; 4°C for 2 years.
- In solvent storage: -80°C for 6 months; -20°C for 1 month.
Medchemexpress LLC (−)-G-Lactone | 43119-28-4 | ≥98.0% | 124.14 | 5 G
(−)-G-Lactone is a synthetic intermediate useful for prostaglandins synthesis. For research use only. We do not sell to patients.
- Synthetic intermediate
- Useful for prostaglandins synthesis
Medchemexpress LLC L-Gulono-1,4-lactone | 1128-23-0 | MFCD00064331 | 178.14 g/mol | C6H10O6 | 1 ML
L-Gulono-1,4-lactone is an endogenous metabolite and precursor to ascorbic acid, supplied as a 10 mM aqueous solution (1 mL) intended for research and analytical applications. It is provided as an analytical standard for qualitative and quantitative assays and is compatible with HPLC, GC, and MS workflows.
- Analytical standard quality suitable for HPLC, GC, and MS
- Provides a stable precursor for ascorbic acid biosynthesis studies
- Ready-to-use aqueous solution for convenient experimental setup
- Small vial volume minimizes waste for low-volume assays
- Intended for research and analytical applications