Pyrroles
Apexbio Technology LLC AHU-377 hemicalcium salt 1369773-39-6 10mM (in 1mL DMSO)
AHU-377 hemicalcium salt (CAS 1369773-39-6) is a hemicalcium salt form of AHU-377 a potent inhibitor of neprilysin (neutral endopeptidase) with an IC50 of 5 nM As a prodrug AHU-377 is enzymatically converted to its active metabolite LBQ657 following ester cleavage AHU-377 is a key component of LCZ696 co-formulated with valsartan at a 1 1 molar ratio functioning as an angiotensin receptor neprilysin inhibitor (ARNI) In vivo studies demonstrate that oral administration of AHU-377 induces dose-dependent blood pressure reduction in DAHI-SS rats though it has less pronounced effects in DOCA-salt hypertensive models AHU-377 is widely studied in cardiovascular research particularly in the context of heart failure and hypertension
eMolecules 1624261-91-1 | ChemScene | (S)-1-(2-Bromo-4-fluorophenyl)ethanamine hydrochloride | 100mg | 687356714 | CS-0196840 | MFCD22988854 | 254.53 | C8H10BrClFN
Ambeed | 4-Fluoro-3-iodobenzaldehyde | 100mg | 672838989 | A822555 | 227609-88-3 | MFCD08236850 | 250.011 | C7H4FIO
If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link:
eMolecules Building Block Tool<|a>
Cayman Chemical Atorvastatin calcium salt hy
An HMG-CoA reductase inhibitor (IC50s = 73, 102, and 0.6 nM for HepG2 cells, human fibroblasts, and rat hepatocytes, respectively)
Medchemexpress LLC (-)-Corey lactone diol | 32233-40-2 | 172.18 | 25 G
(-)-Corey lactone diol is the reduced form of Corey aldehyde. It can be used as a drug intermediate for the synthesis of Beraprost.
- Reduced form of Corey aldehyde
- Can be used as a drug intermediate
- Building block in chemical synthesis
Cayman Chemical SBromoenol lactone
A selective iPLA2β inhibitor; inhibits vasopressin-induced release of arachidonate from cultured rat aortic smooth muscle (A10) cells (IC50 = 2 µM); >1,000-fold selective for iPLA2 versus cPLA2 and 10-fold selective for iPLA2β versus iPLA2γ