Pyrroles
Selleck Chemical LLC BMS-986158-5mg
BMS-986158 is a potent inhibitor of BET with IC50s of 6.6 nM and 5 nM in NCI-H211 small cell lung cancer (SCLC) cells and MDA-MB231 triple negative breast cancer (TNBC) cells, respectively.
eMolecules 1632006-28-0 | Medchem Express | Esaxerenone | 1mg | 446255549 | HY-100471 | 466.48 | C22H21F3N2O4S
Medchem Express | N-deacetylated BMS-202 | 5mg | 446270231 | HY-19745A | 2310135-18-1 | MFCD31382120 | 377.488 | C23H27N3O2
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eMolecules 1435934-25-0 | Medchem Express | A 419259 (trihydrochloride) | 5mg | 446266566 | HY-15764A | MFCD19690922 | 592.01 | C29H37Cl3N6O
Medchem Express | SAR405 R enantiomer | 2mg | 446261348 | HY-12481A | 1946010-79-2 | MFCD29037449 | 443.860 | C19H21ClF3N5O2
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Selleck Chemical LLC Ribociclib
Ribociclib is an orally available and highly specific inhibitor of CDK4 and CDK6 with IC50 of 10 nM and 39 nM Phase 3
Cayman Chemical NdecanoylLHomoserine lactone
A small diffusible signaling molecule involved in quorum sensing, controlling gene expression, and affecting cellular metabolism; applications for this molecule include regulation of virulence and exoproteases
Medchemexpress LLC JMS-17-2 | 1380392-05-1 | MFCD30489012 | 99.2% | 419.95 | C25H26ClN3O | 50MG
JMS-17-2 is a small-molecule research compound that functions as a potent and selective antagonist of the CX3CR1 receptor (IC50 = 0.32 nM). It has been used in preclinical studies to impair metastatic seeding and colonization of breast cancer cells. The material is supplied as a high-purity solid with recommended cold storage for prepared solutions to preserve stability.
- Chemical formula: C25H26ClN3O.
- Molecular weight: 419.95 g·mol-1.
- High purity suitable for research use.
- Appearance: white to off-white solid.
- Storage: store solid at 4°C protected from light; store solutions at -20°C to -80°C for longer-term stability.
- Applications: in vitro and in vivo studies of CX3CR1-mediated processes and metastasis models.
- Available in multiple pack formats including small mg quantities and ready-to-use DMSO solutions.
Cayman Chemical RBromoenol lactone
A selective iPLA2γ inhibitor (IC50 = ~0.6 µM); selective for iPLA2γ over iPLA2β at 20-30 µM