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Filtered Search Results
Cayman Chemical 7 Z 10 Z 13 ZHexadecatrienoic
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7 Z 10 Z 13 ZHexadecatrienoic
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000378490 DOTA-GA-MALEIMIDE 50MG
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eMolecules 3-CBZ-AMINOPROPANAL 25G
5000160791 3-CBZ-AMINOPROPANAL 25G
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Medchemexpress LLC (Rac)-5-Hydroxymethyl Tolterodine hydrochloride | 250214-40-5 | C22H32ClNO2 | 500 MG
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(Rac)-5-Hydroxymethyl Tolterodine hydrochloride is an active metabolite of Tolterodine, functioning as a muscarinic acetylcholine receptor (mAChR) antagonist. It exhibits Ki values of 2.3 nM, 2 nM, 2.5 nM, 2.8 nM, and 2.9 nM for M1, M2, M3, M4, and M5 receptors, respectively. This compound is suitable for research related to overactive bladder, demonstrating competitive inhibition of carbachol-induced contraction in guinea-pig urinary bladder strips and significant binding to muscarinic receptors.
- Acts as a muscarinic acetylcholine receptor (mAChR) antagonist
- Active metabolite of Tolterodine
- Inhibits carbachol-induced contraction of isolated guinea-pig urinary bladder strips
- Exhibits significant binding activity to muscarinic receptors in various tissues, with a longer duration in the bladder
- Suitable for overactive bladder research
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000429989 CY7.5 MALEIMIDE 5MG
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Medchemexpress LLC (3R,5S)-5-([1,1′-Biphenyl]-4-ylmethyl)-3-methyl-2-pyrrolidinone | 1038924-70-7 | 95.5% | C18H19NO | 100 MG
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This biological molecule, (3R,5S)-5-([1,1′-Biphenyl]-4-ylmethyl)-3-methyl-2-pyrrolidinone, is a white to light yellow solid intended for research use only.
- Purity: 95.5%
- Molecular weight: 265.35 g/mol
- Chemical formula: C18H19NO
- Appearance: Solid, white to light yellow
- Solubility in DMSO: 100 mg/mL (376.86 mM)
- Storage as powder: -20°C for 3 years, 4°C for 2 years
- Storage in solvent: -80°C for 6 months, -20°C for 1 month
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Medchemexpress LLC SK1-I (BML-258) | 1072443-89-0 | 98.8% | 277.40 | C17H27NO2 | 5 MG
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SK1-I (BML-258) is a sphingosine analog and an isozyme-specific competitive inhibitor of sphingosine kinase 1 (SPHK1) with a reported Ki of about 10 μM. It enhances autophagy and has demonstrated antitumor activity. Intended for research use only.
- Isozyme-specific SPHK1 inhibition (Ki ≈ 10 μM).
- Sphingosine analog scaffold.
- High purity: 98.83%.
- Molecular weight 277.40 g/mol; formula C17H27NO2.
- Available as small solid quantities and as a 10 mM solution in DMSO.
- For research use only; not for human or veterinary use.
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Medchemexpress LLC (Rac)-Reparixin | 957407-64-6 | C14H21NO3S | 2 MG
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(Rac)-Reparixin is an isomer of Reparixin and serves as an experimental control. It is known as a non-competitive allosteric inhibitor, effectively targeting the chemokine receptors CXCR1 and CXCR2 with IC50s of 1 nM and 100 nM, respectively.
- Isomer of Reparixin
- Used as an experimental control
- Non-competitive allosteric inhibitor
- Targets chemokine receptors CXCR1 and CXCR2
- Relevant for research in inflammation/immunology, endocrinology, and cancer
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ILEX LIFE SCIENCES LLC PAN Biotech Trypsin Inhibitor Solution 1 mg per ml sterile 600 ML 1/EA
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PAN-Biotech Trypsin Inhibitor Solution 1 mg/ml 6 x 100 ml DESCRIPTION A sterile solution of plant-based inhibitors against trypsin and in some effect to chymotrypsin and plasmin does not inhibit metalloproteases tissue based kallikrein and acid or thioproteases APPLICATION Inhibiting trypsin activity in serum-free culture of adherent cells In serum-free culture the natural neutralizing effect of serum trypsin inhibitors is absent thus it is crucial to completely block proteolytic activity from trypsin after detachment of the cells ADVANTAGE Trypsin Inhibitor Solution contains protease inhibitors as well as growth promoting agents After detachment and re-suspension in serum-free medium Trypsin Inhibitor Solution supports the recovery attachment and spreading of the cells The usual centrifugation step to remove trypsin inhibitor from the cells should be omitted with this product This time-saving feature facilitates a more convenient efficient serum-free cell culture
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Medchemexpress LLC (E/Z)-tyrphostin AG490 | 134036-52-5 | 99.7% | 294.30 g·mol⁻¹ | C17H14N2O3 | 25 MG
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(E/Z)-AG490 is the racemic mixture of the E and Z isomers of tyrphostin AG490, a small-molecule tyrosine kinase inhibitor commonly used in research to probe EGFR, JAK2/3, and STAT3 signaling. Provided as a high-purity solid, it is suitable for biochemical and cellular assays; powder storage at -20°C preserves stability, with specific solvent storage guidance for solutions.
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Medchemexpress LLC (Rac)-EBET-1055 | 3031540-65-2 | 97.2% | 923.02 | 25 MG
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(Rac)-EBET-1055 is the racemate of EBET-1055. It is a bromodomain and extra-terminal (BET) PROTAC degrader that effectively inhibits the growth of pancreatic ductal adenocarcinoma (PDAC) and simultaneously modulates cancer-associated fibroblast (CAF) activity, upregulating all reporter gene activities in organoid co-cultures.
- Racemate of EBET-1055
- Bromodomain and extra-terminal (BET) PROTAC degrader
- Inhibits the growth of pancreatic ductal adenocarcinoma (PDAC)
- Modulates cancer-associated fibroblast (CAF) activity
- Upregulates reporter gene activities in organoid co-cultures
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Medchemexpress LLC BODIPY 493/503 methyl bromide | 216434-81-0 | 98.0% | 341.01 | 50 MG
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BODIPY 493/503 methyl bromide | 216434-81-0 | 98.0% | 341.01 | 50 MG
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Medchemexpress LLC (E/Z)-Zotiraciclib | 937270-47-8 | C23H24N4O | 1 ML
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(E/Z)-Zotiraciclib is a potent inhibitor of CDK2, JAK2, and FLT3, with IC50s of 13, 73, and 56 nM, respectively. It effectively inhibits the proliferation of cancer cells and is intended for cancer research.
- Potent inhibitor of CDK2, JAK2, and FLT3
- Inhibits proliferation of cancer cells including HL-60, HCT-116, RAMOS, COLO205, and DU145
- Potently inhibits the CDK2 biomarker pRb in HCT-116 and MV4-11 cells
- Demonstrates significant tumor growth inhibition in HCT-116 colon cancer cell xenografts (82% TGI)
- Inhibits tumor growth in lymphoma Ramos cells xenografts (42% oral, 63% intraperitoneal TGI)
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000383745 CBZ-NH-PEG3-CH2COOH 250MG
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Medchemexpress LLC Cbz-NH-PEG4-C2-acid | 756526-00-8 | MFCD11041139 | >95.0% | 399.44 g·mol⁻¹ | C19H29NO8 | 100 MG
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Cbz-NH-PEG4-C2-acid is a Cbz-protected PEG-based linker containing a PEG4 spacer and a two-carbon carboxylic acid terminus, intended for use in PROTAC synthesis and related medicinal chemistry applications. The protected amine allows selective deprotection and downstream coupling to assemble bifunctional molecules.
- Cbz-protected amine for selective deprotection.
- PEG4 spacer provides linker flexibility and improved solubility.
- C2 carboxylic acid terminus enables standard coupling chemistries.
- Suitable for PROTAC and bioconjugation synthesis workflows.
- Available in multiple pack sizes for research-scale use.
- Characterized by molecular formula and molecular weight; consult SDS for purity details.
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