Pyrrolidines
Medchemexpress LLC Boc-NH-PEG3 | 139115-92-7 | MFCD07357496 | ≥98.0% | 249.30 | C11H23NO5 | 1 G
Boc-NH-PEG3 is a Boc-protected PEG3 (triethylene glycol) linker used as a short, hydrophilic spacer in the chemical synthesis of PROTACs and related bioconjugates. It provides a flexible, soluble spacer terminated with a Boc-protected amine that can be deprotected and further functionalized for coupling to ligands or tags. The compound is supplied at high purity and in research-scale pack sizes suitable for synthetic workflows.
- Boc-protected terminal amine for orthogonal deprotection.
- Triethylene glycol spacer gives flexibility and solubility.
- Suitable for PROTAC and general bioconjugation chemistry.
- High purity, suitable for synthetic applications.
- Available in small pack sizes for research-scale synthesis.
- Stable when stored under recommended conditions.
Apexbio Technology LLC Z-VDVAD-FMK 210344-92-6 10mg
Z-VDVAD-FMK (CAS 210344-92-6) is an irreversible cell-permeable inhibitor primarily targeting caspase-2 with additional inhibitory effects on caspases-3 and -7 It functions by binding covalently to the active site of caspase enzymes thereby interrupting downstream apoptotic signaling processes In cellular studies treatment with Z-VDVAD-FMK suppresses caspase-2-dependent cytochrome c release triggered by apoptotic inducers such as etoposide Moreover Z-VDVAD-FMK effectively reduces apoptosis-related responses including cellular detachment DNA fragmentation and cleavage of PARP2 in endothelial cells exposed to oxyhemoglobin This small molecule serves as a pivotal tool for dissecting caspase pathways and investigating apoptosis-mediated cellular outcomes in biomedical research
Apexbio Technology LLC Z-VDVAD-FMK 210344-92-6 5mg
Z-VDVAD-FMK (CAS 210344-92-6) is an irreversible cell-permeable inhibitor primarily targeting caspase-2 with additional inhibitory effects on caspases-3 and -7 It functions by binding covalently to the active site of caspase enzymes thereby interrupting downstream apoptotic signaling processes In cellular studies treatment with Z-VDVAD-FMK suppresses caspase-2-dependent cytochrome c release triggered by apoptotic inducers such as etoposide Moreover Z-VDVAD-FMK effectively reduces apoptosis-related responses including cellular detachment DNA fragmentation and cleavage of PARP2 in endothelial cells exposed to oxyhemoglobin This small molecule serves as a pivotal tool for dissecting caspase pathways and investigating apoptosis-mediated cellular outcomes in biomedical research
Apexbio Technology LLC Z-VDVAD-FMK 210344-92-6 25mg
Z-VDVAD-FMK (CAS 210344-92-6) is an irreversible cell-permeable inhibitor primarily targeting caspase-2 with additional inhibitory effects on caspases-3 and -7 It functions by binding covalently to the active site of caspase enzymes thereby interrupting downstream apoptotic signaling processes In cellular studies treatment with Z-VDVAD-FMK suppresses caspase-2-dependent cytochrome c release triggered by apoptotic inducers such as etoposide Moreover Z-VDVAD-FMK effectively reduces apoptosis-related responses including cellular detachment DNA fragmentation and cleavage of PARP2 in endothelial cells exposed to oxyhemoglobin This small molecule serves as a pivotal tool for dissecting caspase pathways and investigating apoptosis-mediated cellular outcomes in biomedical research