Quinolines and derivatives

Aromatic organic heterocyclic compounds that contain a benzene ring fused with a six-membered ring that contains one nitrogen atom and five carbon atoms. Includes compounds that are derived from quinolines.

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2,086 – 2,100 of 4,396 results

2,086

Medchemexpress LLC 38-azido-3,6,9,12,15,18,21,24,27,30,33,36-dodecaoxaoctatriacontan-1-amine | 2803478-25-1 | 98.0% | 614.73 | C26H54N4O12 | 100 MG

Azido-PEG12-amine is an azide-terminated polyethylene glycol (PEG12) linker bearing a terminal primary amine used in bioconjugation and click-chemistry applications.

Azide group enables click chemistry (azide-alkyne cycloaddition).
Terminal primary amine reacts with carboxylic acids, activated NHS esters, and carbonyls.
PEG12 spacer increases aqueous solubility and reduces steric hindrance.
Molecular weight 614.73; formula C26H54N4O12.
High purity (98.0% by NMR) with 1H NMR and MS consistent with structure.
Storage: sealed, away from moisture and light; in solvent store at -80°C (6 months) or -20°C (1 month).

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2,087

Ambeed AMBEED

5000847127 M-PEG7-AMINE 250MG

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2,088

Medchemexpress LLC Amisulpride | 71675-85-9 | MFCD00866691 | 99.8% | C17H27N3O4S | 200 MG

Amisulpride is a racemic (50:50) mixture of R-Amisulpride and S-Amisulpride. It acts as a dopamine D2/D3 receptor antagonist with Ki values of 2.8 nM for human dopamine D2 and 3.2 nM for human dopamine D3 receptors. Amisulpride also functions as a 5-HT7 receptor antagonist with a Ki of 44 nM, making it suitable for use in psychiatric research.

Racemic mixture
Dopamine D2/D3 receptor antagonist
5-HT7 receptor antagonist
Suitable for psychiatric research
D3 receptor Ki: 3.2 nM
Human D2 receptor Ki: 2.8 nM
5-HT7 receptor Ki: 44 nM
Inhibits quinpirole-elicited [3H]thymidine incorporation
Increases dopamine release from rat striatum slices
Increases dopamine synthesis in rat striatum and limbic system
Increases extracellular dopamine levels
Decreases striatal ACh levels
Increases duration of swimming behavior

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2,089

Medchemexpress LLC Trilostane (Win 24540) | 13647-35-3 | 99.9% | C20H27NO3 | 200 MG

Trilostane (Win 24540) is a competitive and orally active 3-β-hydroxysteroiddehydrogenase (3β-HSD) inhibitor. It is a synthetic nonhormonal steroid that can be used for the research of breast cancer and prostate cancer.

Competitive and orally active 3-β-hydroxysteroiddehydrogenase (3β-HSD) inhibitor.
Synthetic nonhormonal steroid.
Used for the research of breast cancer and prostate cancer.
Influences pregnenolone metabolism in adrenal cortex.
Selectively inhibits pregnenolone converting to progesterone in the adrenal gland.
Effectively controls pituitary-dependent hyperadrenocorticism (PDH) in dogs.

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2,090

eMolecules 101-38-2 | Gibbs reagent | TargetMol | MFCD00001611 | 210.440 | C6H2Cl3NO | 0.000 | ClN=C1C=C(Cl)C(=O)C(Cl)=C1 | 200mg | 761052535

Gibbs reagent | TargetMol | 101-38-2 | MFCD00001611 | 210.440 | C6H2Cl3NO | 0.000 | ClN=C1C=C(Cl)C(=O)C(Cl)=C1 | 200mg | 761052535

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2,091

Medchemexpress LLC Azido-PEG1-amine | 464190-91-8 | ≥98.0% | C4H10N4O | 100 MG

Azido-PEG1-amine is a PEG-based PROTAC linker designed for the synthesis of PROTACs. It functions as a click chemistry reagent due to its Azide group, enabling copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules possessing DBCO or BCN groups. PROTACs utilize two ligands connected by a linker to target an E3 ubiquitin ligase and a protein of interest, facilitating selective degradation via the intracellular ubiquitin-proteasome system.

PEG-based PROTAC linker
Functions as a click chemistry reagent
Enables copper-catalyzed azide-alkyne cycloaddition (CuAAc)
Participates in strain-promoted alkyne-azide cycloaddition (SPAAC)
Utilized in PROTAC synthesis
Relevant for cancer targeted therapy

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2,092

Medchemexpress LLC Palmitoylethanolamide | 544-31-0 | MFCD00020562 | 99.86% | 299.49 | 200 MG

Palmitoylethanolamide (Standard) is the analytical standard for Palmitoylethanolamide, an active endogenous compound. It is intended for research and analytical applications, and can be used for preventing virus infection of the respiratory tract.

Analytical standard for Palmitoylethanolamide.
Intended for research and analytical applications.
Can be used for preventing virus infection of the respiratory tract.
High purity of 99.86%.
Available in multiple quantities for various research needs.
Suitable for qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS.

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2,093

Medchemexpress LLC Benzyl-PEG4-amine 1g

Benzyl-PEG4-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]

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2,094

Chemscene CHEMSCENE

5000578908 BENZYL 3-AMINOPROPYL CARBA 10G

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2,095

Medchemexpress LLC TCO-SS-amine | >=95.0% | 304.47 | C13H24N2O2S2 | 5 MG

TCO-SS-amine is a cleavable antibody-drug conjugate (ADC) linker containing a trans-cyclooctene (TCO) group that enables inverse electron demand Diels-Alder (iEDDA) click reactions with tetrazine-functionalized partners. It is used as a disulfide-cleavable linker in ADC synthesis and as a bioorthogonal click chemistry reagent.

Cleavable disulfide linker for ADC synthesis.
Contains a TCO group for iEDDA click chemistry with tetrazines.
Molecular formula: C13H24N2O2S2.
Molecular weight: 304.47 g/mol.
Purity: ≥95.0%.
Storage: -20°C, protect from light; in solvent: -80°C up to 6 months.
Available in small research pack sizes such as 5 mg.

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2,096

Medchemexpress LLC Prostaglandin H2 | 42935-17-1 | MFCD00222079 | ≥95.0% | 352.47 | 50 UG

Prostaglandin H2 (PGH2) is an endothelium-derived contracting factor that can cause vasoconstriction. It serves as a common precursor for all prostaglandins and is generated by cells expressing cyclooxygenases. PGH2 can activate PGD2 receptors, induce eosinophil migration, inhibit platelet aggregation, and accelerate the formation of amyloid β1-42 oligomers. It is utilized in research concerning inflammation and neurological conditions, such as Alzheimer's disease.

Induces eosinophil migration.
Inhibits platelet aggregation.
Accelerates formation of amyloid β1-42 oligomers.
Used in inflammation research.
Used in neurological disease research.

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2,097

Medchemexpress LLC Amifostine (trihydrate) | 112901-68-5 | 100.0% | 200 MG

Amifostine trihydrate is a broad-spectrum cytoprotective agent and radioprotector. It selectively protects normal tissues from damage caused by radiation and chemotherapy. It acts as a potent hypoxia-inducible factor-α1 (HIF-α1) and p53 inducer, protecting cells by scavenging oxygen-derived free radicals. It also reduces renal toxicity and exhibits antiangiogenic action.

Broad-spectrum cytoprotective agent
Radioprotector
Selectively protects normal tissues from radiation and chemotherapy damage
Potent HIF-α1 and p53 inducer
Scavenges oxygen-derived free radicals
Reduces renal toxicity
Exhibits antiangiogenic action
Protects against tert-Butyl hydroperoxide (TBHP)-induced cell damage
Reduces H9c2 cell apoptosis
Provides protection against myocardial ischemia/reperfusion injury

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2,098

Promega Corporation GLOMAX R GALAXY OPERATIONAL Q

PRSA1501 GLOMAX R GALAXY OPERATIONAL Q

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2,099

Medchemexpress LLC Amino-PEG8-amine | 82209-36-7 | ≥98.0% | 100 MG

Amino-PEG8-amine is a PEG-based (8 units) PROTAC linker used in the synthesis of PROTACs. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

PROTAC linker
Used in the synthesis of PROTACs
Contains two different ligands connected by a linker; one for an E3 ubiquitin ligase and the other for the target protein
Exploits the intracellular ubiquitin-proteasome system to selectively degrade target proteins

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2,100

Medchemexpress LLC Kaempferol | 520-18-3 | MFCD00004543 | 99.9% | C15H10O6 | 200 MG

Kaempferol is a naturally occurring flavonoid found in various edible plants. This compound functions as an estrogen receptor alpha inhibitor in breast cancer cells and promotes apoptosis in glioblastoma and lung cancer cells through MEK-MAPK activation. It is recognized as a human endogenous metabolite.

Inhibits estrogen receptor alpha expression in breast cancer cells.
Induces apoptosis in glioblastoma and lung cancer cells.
Demonstrates anti-inflammatory activity.
Exhibits antioxidant activity in human HepG2 cells.
Shows antiproliferative activity against certain human cancer cell lines.
Displays antiallergic activity.
Demonstrates antiviral activity against influenza A virus.
Inhibits melanogenesis.
Inhibits procoagulant activity.
Induces osteoclast apoptosis.
Exhibits antiaggregatory activity in human platelets.

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Quinolines and derivatives

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Medchemexpress LLC 38-azido-3,6,9,12,15,18,21,24,27,30,33,36-dodecaoxaoctatriacontan-1-amine | 2803478-25-1 | 98.0% | 614.73 | C26H54N4O12 | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Amisulpride | 71675-85-9 | MFCD00866691 | 99.8% | C17H27N3O4S | 200 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Trilostane (Win 24540) | 13647-35-3 | 99.9% | C20H27NO3 | 200 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Azido-PEG1-amine | 464190-91-8 | ≥98.0% | C4H10N4O | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Palmitoylethanolamide | 544-31-0 | MFCD00020562 | 99.86% | 299.49 | 200 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Benzyl-PEG4-amine 1g Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Chemscene CHEMSCENE Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC TCO-SS-amine | >=95.0% | 304.47 | C13H24N2O2S2 | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Prostaglandin H2 | 42935-17-1 | MFCD00222079 | ≥95.0% | 352.47 | 50 UG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Amifostine (trihydrate) | 112901-68-5 | 100.0% | 200 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Amino-PEG8-amine | 82209-36-7 | ≥98.0% | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Kaempferol | 520-18-3 | MFCD00004543 | 99.9% | C15H10O6 | 200 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More