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Filtered Search Results
TARGETMOL CHEMICALS INC ALFLUTINIB MESYLATE 5MG
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502693646 ALFLUTINIB MESYLATE 5MG
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TARGETMOL CHEMICALS INC BETA-ANHYDROICARITIN 25MG
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502693690 BETA-ANHYDROICARITIN 25MG
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TARGETMOL CHEMICALS INC DABIGATRAN ETEXILATE 100MG
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502693600 DABIGATRAN ETEXILATE 100MG
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Medchemexpress LLC Deferoxamine (mesylate) (Standard) | 138-14-7 | 99.8% | 25 MG
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Deferoxamine mesylate (Deferoxamine B mesylate) is an iron chelator that binds to Fe(III) and many other metal cations. It is widely used to reduce iron accumulation and deposition in tissues. It upregulates HIF-1α levels with good antioxidant activity and also shows anti-proliferative activity, inducing apoptosis and autophagy in cancer cells. Deferoxamine mesylate can be used in studies of diabetes, neurodegenerative diseases, as well as anti-cancer and anti-COVID-19 research.
- Binds to Fe(III) and many other metal cations.
- Reduces iron accumulation and deposition in tissues.
- Upregulates HIF-1α levels.
- Exhibits good antioxidant activity.
- Shows anti-proliferative activity.
- Induces apoptosis and autophagy in cancer cells.
- Used in studies of diabetes and neurodegenerative diseases.
- Used in anti-cancer and anti-COVID-19 research.
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Medchemexpress LLC Deferoxamine mesylate (standard) | 138-14-7 | 99.47% | 50 MG
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Deferoxamine mesylate (Standard) is an analytical standard intended for research and analytical applications. It functions as an iron chelator, binding to Fe(III) and other metal cations, thereby reducing iron accumulation and deposition in tissues. This compound also upregulates HIF-1α levels and exhibits good antioxidant activity, along with anti-proliferative activity that can induce apoptosis and autophagy in cancer cells.
- Used in studies related to diabetes, neurodegenerative diseases, anti-cancer research, and anti-COVID-19 research
- Serves as a reference standard for assays
- Frequently utilized in qualitative, quantitative, and methodological research experiments such as HPLC, GC, and MS
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TARGETMOL CHEMICALS INC SAFINAMIDE MESYLATE 25MG
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Also available in 2 mg 5 mg 10 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Safinamide mesylate (EMD 1195686 mesylate) a mesylate salt of Safinamide can reversibly and specifically inhibit MAO-B (IC50 98 nM) has 5918-fold selectivity against MAO-A. purity: 98%
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Medchemexpress LLC Bromocriptine mesylate | 22260-51-1 | 99.90% | 200 MG
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Bromocriptine mesylate is a potent dopamine D2/D3 receptor agonist, binding to the D2 dopamine receptor with a pKi of 8.05. It is permeable to the blood-brain barrier. This compound also acts as a strong inhibitor of brain nitric oxide synthase (NOS) with an IC50 of 10±2 μM for purified neuronal NOS, and poorly inhibits inducible macrophage NOS (IC50>100 μM). Additionally, it is a potent inhibitor of CYP3A4, with a calculated IC50 value of 1.69 μM.
- Potent dopamine D2/D3 receptor agonist
- Permeable to the blood-brain barrier
- Strong inhibitor of brain nitric oxide synthase (NOS)
- Potent inhibitor of CYP3A4
- Shows anti-immobility action in mice (in FST and TST)
- Potentiates the anti-immobility action of MPE
- Decreases static mechanical allodynia (SMA) score in rats
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Medchemexpress LLC Firmonertinib mesylate | 2130958-55-1 | 100.0% | 664.70 | 50 MG
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Firmonertinib mesylate is an orally active, mutant-selective, and blood-brain barrier penetrant EGFR inhibitor. It inhibits EGFR active mutations as well as the T790M acquired resistant mutation. It has potential for the research of cancer diseases, especially advanced non-small cell lung cancer (NSCLC) with EGFR ex20ins mutation.
- Orally active
- Mutant-selective
- Blood-brain barrier penetrant EGFR inhibitor
- Inhibits EGFR active mutations and T790M acquired resistant mutation
- Potential for research of cancer diseases, especially advanced NSCLC with EGFR ex20ins mutation
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000656217 SULFO-CYANINE5.5 ALK 5MG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000656946 TYROSYLPROTEIN SULFO 100UG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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5000665661 PT2399 200MG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000691215 TC-O 9311 200MG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000692745 WATER SOLUBLE SILK F 200MG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000696929 ACALABRUTINIB 200MG
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Apexbio Technology LLC GSK1070916 942918-07-2 200mg
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GSK1070916 (CAS 942918-07-2) is a selective ATP-competitive inhibitor targeting Aurora kinase B and C displaying Ki values of 0 38 nM and 1 5 nM respectively The compound demonstrates marked selectivity over Aurora kinase A with IC50 values of approximately 5 nM (Aurora B) versus 1259 nM (Aurora A) In vitro studies show that GSK1070916 inhibits proliferation of human lung cancer cells (A549) with an EC50 of roughly 7 nM Additionally the compound effectively reduces phosphorylation of histone H3 an Aurora B substrate and exhibits tumor growth inhibition in HL-60 xenograft mouse models GSK1070916 is utilized in tumor biology research investigating Aurora kinase signaling pathways
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