Quinolines and derivatives
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Filtered Search Results
Aobchem AOBCHEM
5000875279 1- 2-FLUORO-3-ISOPROPOXY-5- TR
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5000738411 CRBN LIGAND-148 100MG
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Ambeed AMBEED
5000886629 8-HYDROXYQUINOLINE-2-CAR 5G
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Ambeed AMBEED
5000883424 S-55667788-OCTAHYDRO-11- 25G
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Medchemexpress LLC 1-(4-(aminomethyl)benzyl)-2-butyl-1H-imidazo[4,5-c]quinolin-4-amine dihydrochloride | 1620278-72-9 | MFCD31657341 | 99.7% | 432.39 g/mol | C22H27Cl2N5 | 1 ML
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TLR7/8 agonist 1 dihydrochloride is a dual-agonistic imidazoquinoline research compound that activates toll-like receptors 7 and 8 to induce innate immune responses. It is used in cell-based assays and in vivo studies to stimulate immune signaling and can serve as a derivatizable precursor for covalent labeling while retaining biological activity.
- Dual agonist of toll-like receptors 7 and 8, inducing innate immune signaling.
- Low-nanomolar agonistic potency (≈50 nM for TLR7, ≈55 nM for TLR8).
- Available as a DMSO solution for convenient dosing in cell assays.
- Suitable for use in cell-based and in vivo immunostimulatory studies.
- Precursor amenable to covalent modification without significant loss of activity.
- Stable when stored sealed at 4°C; in solution recommended -80°C for long-term storage.
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Medchemexpress LLC Mal-C6-amine TFA | 731862-92-3 | MFCD11519191 | 99.7% | 310.27 g/mol | C12H17F3N2O4 | 250 MG
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Mal-C6-amine (TFA) is an alkyl chain-based PROTAC linker supplied as the trifluoroacetate salt for use in the synthesis of proteolysis-targeting chimeras. It provides a maleimide-reactive terminus and a six-carbon spacer that enable thiol conjugation and optimized linker length for degrader constructs.
- Maleimide-reactive terminus for selective conjugation to thiols.
- C6 alkyl spacer provides flexibility and appropriate linker length.
- Trifluoroacetate salt form for improved handling and solubility.
- High purity suitable for chemical synthesis (listed as 99.73%).
- Soluble in DMSO for convenient formulation and reactions.
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000383875 VII-31 10MM 1ML
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000734643 3 6-DINITRO-9H-CARBA 1G
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Medchemexpress LLC Mefloquine | 53230-10-7 | 99.96% | 378.31 | 1 ML
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Mefloquine is an orally active and potent quinoline antimalarial agent that also acts as an anti-SARS-CoV-2 entry inhibitor. It is used in research for:
- K+ channel (KvQT1/minK) antagonist with an IC50 of approximately 1 μM.
- Malaria studies.
- Systemic lupus erythematosus research.
- Cancer research.
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Medchemexpress LLC O-tert-Butyl-N-carbobenzoxy-L-serine methyl ester | 1872-59-9 | 309.36 | 10 G
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O-tert-Butyl-N-carbobenzoxy-L-serine methyl ester is a serine derivative. Amino acids and amino acid derivatives have been commercially used as ergogenic supplements.
- Influence the secretion of anabolic hormones.
- Supply fuel during exercise.
- Enhance mental performance during stress related tasks.
- Prevent exercise induced muscle damage.
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Medchemexpress LLC Quinine sulfate hydrate | 6119-70-6 | 99.97% | 409.48 | 25 G
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Quinine sulfate hydrate is an orally active alkaloid extracted from cinchona bark, primarily used in anti-malarial studies. It also functions as a potassium channel inhibitor, inhibiting WT mouse Slo3 (KCa5.1) channel currents.
- Orally active alkaloid
- Extracted from cinchona bark
- Used in anti-malarial studies
- Potassium channel inhibitor
- Inhibits WT mouse Slo3 (KCa5.1) channel currents
- Inhibits DENV proliferation and reduces viral RNA/protein levels
- Shows tumor-suppressing effects
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Ambeed AMBEED
5000885089 4-AMINO-5-CHLORO-2-ETHOX 25G
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eMolecules 4965-36-0 | 7-Bromoquinoline | Accela ChemBio | MFCD03695823 | 208.058 | C9H6BrN | 95.000 | Brc1ccc2cccnc2c1 | 5g | 135709841
7-Bromoquinoline | Accela ChemBio | 4965-36-0 | MFCD03695823 | 208.058 | C9H6BrN | 95.000 | Brc1ccc2cccnc2c1 | 5g | 135709841
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Medchemexpress LLC Oltipraz | 64224-21-1 | 99.9% | 226.34 | C8H6N2S3 | 200MG
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Oltipraz is a research-grade small molecule that functions as an Nrf2 activator and HIF-1α inhibitor. Supplied as a brown-to-red solid powder for laboratory research, it is intended for use in mechanistic studies of oxidative stress, phase II detoxification, and hypoxia signaling; not for human consumption.
- High purity (99.9%).
- Molecular formula C8H6N2S3; molecular weight 226.34 g/mol.
- Available in multiple pack sizes including 200 mg vials.
- Solid, brown-to-red appearance suitable for standard laboratory handling.
- Storage: powder at -20°C (3 years) or 4°C (2 years); in solvent at -80°C (1 year) or -20°C (6 months).
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Ambeed AMBEED
5000882585 5-METHYLQUINOLINE 10G
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