Quinolines and derivatives
Medchemexpress LLC Tigecycline | 220620-09-7 | 99.95% | 200 MG
Tigecycline (GAR-936) is a broad-spectrum glycylcycline antibiotic. It has been shown to inhibit AML2 and HL-60 cells, with specific IC50 values. Its activity extends to bacterial strains, demonstrating a mean inhibitory concentration (MIC) of approximately 125 ng/mL for E. coli (MG1655 strain), and MIC50 and MIC90 values of 1 and 2 mg/L, respectively, for Acinetobacter baumannii.
- Broad-spectrum glycylcycline antibiotic
- Inhibits AML2 and HL-60 cells in vitro
- Demonstrates activity against E. coli and Acinetobacter baumannii
- Light yellow to orange solid appearance
- Derived from microorganisms
- Reduced tumor volume and weight in an AML xenograft model
Apexbio Technology LLC Baricitinib (LY3009104, INCB028050) 1187594-09-7 200mg
Baricitinib (LY3009104 INCB028050 CAS 1187594-09-7) is an orally bioavailable ATP-competitive inhibitor targeting Janus kinases JAK1 and JAK2 It also exhibits moderate inhibition of TYK2 and weaker inhibition against JAK3 In biochemical assays baricitinib inhibits JAK1 and JAK2 with IC50 values of 5 9 nM and 5 7 nM respectively At concentrations below 50 nM baricitinib suppresses intracellular signaling mediated by several pro-inflammatory cytokines notably IL-6 and IL-23 Due to its mechanistic profile baricitinib is actively explored in inflammatory disease research such as rheumatoid arthritis
Medchemexpress LLC 7-Bromoisoquinoline | 58794-09-5 | 99.98% | C9H6BrN | 1 G
7-Bromoisoquinoline is a brominated isoquinoline and synthetic precursor. It is utilized to construct the isoquinoline functional group at the C17 position of target molecules, serving as a key synthetic intermediate for the synthesis of cortistatin A-derived anti-angiogenic steroidal analogs.
- Purity of 99.98%
- Appears as a solid, white to light brown
- Molecular formula: C9H6BrN
- Molecular weight: 208.06
- CAS number: 58794-09-5
- Powder storage: -20°C for 3 years, 4°C for 2 years
- In solvent storage: -80°C for 6 months, -20°C for 1 month
- Soluble in DMSO at 100 mg/mL
Medchemexpress LLC 7-APRA | 120709-09-3 | ≥95.0% | 240.28 | 10 G
7-APRA is a semi-synthetic intermediate of cephalosporin antibiotics. It possesses antibacterial activity and is primarily utilized in the synthesis of Cefaclor and Cefprozil.
- Possesses antibacterial activity
- Used in the synthesis of cephalosporin antibiotics
- Intermediate for drug synthesis
Medchemexpress LLC 7-APRA | 120709-09-3 | ≥95.0% | 240.28 | 25 G
7-APRA is a semi-synthetic intermediate of cephalosporin antibiotics. It possesses antibacterial activity and is primarily utilized in the synthesis of Cefaclor and Cefprozil. It appears as an off-white to light yellow solid.
- Possesses antibacterial activity
- Utilized in the synthesis of Cefaclor and Cefprozil
- Solid appearance
- Off-white to light yellow color
eMolecules 4'-BROMO-4-ETHOXY-2,3-DIFLUORO-1,1'-BIPHENYL | 470461-09-7 | MFCD25460355 | 1g
AstaTech | 4'-BROMO-4-ETHOXY-2,3-DIFLUORO-1,1'-BIPHENYL | 1g | 268489232 | 36842 | 97.000 | 470461-09-7 | MFCD25460355 | 313.142 | C14H11BrF2O
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eMolecules Pharmablock 7-bromoisoquinoline 100mg 551128246 PBN2011270 0 000 58794-09-5 MFCD07368661 208 058 C9H6BrN
Pharmablock 7-bromoisoquinoline 100mg 551128246 PBN2011270 0 000 58794-09-5 MFCD07368661 208 058 C9H6BrN
eMolecules Pharmablock 7-bromoisoquinoline 25mg 551259458 PBN2011270 0 000 58794-09-5 MFCD07368661 208 058 C9H6BrN
Pharmablock 7-bromoisoquinoline 25mg 551259458 PBN2011270 0 000 58794-09-5 MFCD07368661 208 058 C9H6BrN
eMolecules Pharmablock 7-bromoisoquinoline 500mg 551128248 PBN2011270 0 000 58794-09-5 MFCD07368661 208 058 C9H6BrN
Pharmablock 7-bromoisoquinoline 500mg 551128248 PBN2011270 0 000 58794-09-5 MFCD07368661 208 058 C9H6BrN
eMolecules Pharmablock 7-bromoisoquinoline 250mg 551328802 PBN2011270 0 000 58794-09-5 MFCD07368661 208 058 C9H6BrN
Pharmablock 7-bromoisoquinoline 250mg 551328802 PBN2011270 0 000 58794-09-5 MFCD07368661 208 058 C9H6BrN
eMolecules Pharmablock 7-bromoisoquinoline 50mg 551128245 PBN2011270 0 000 58794-09-5 MFCD07368661 208 058 C9H6BrN
Pharmablock 7-bromoisoquinoline 50mg 551128245 PBN2011270 0 000 58794-09-5 MFCD07368661 208 058 C9H6BrN
eMolecules Apollo Scientific US 7-Bromoisoquinoline 250mg 870070418 OR40468 0 000 58794-09-5 MFCD07368661 208 058 C9H6BrN
Apollo Scientific US 7-Bromoisoquinoline 250mg 870070418 OR40468 0 000 58794-09-5 MFCD07368661 208 058 C9H6BrN
eMolecules Apollo Scientific - Building Blocks 7-Bromoisoquinoline 250mg 553346418 OR40468 0 000 58794-09-5 MFCD07368661 208 058 C9H6BrN
Apollo Scientific - Building Blocks 7-Bromoisoquinoline 250mg 553346418 OR40468 0 000 58794-09-5 MFCD07368661 208 058 C9H6BrN
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