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Quinolines and derivatives

Aromatic organic heterocyclic compounds that contain a benzene ring fused with a six-membered ring that contains one nitrogen atom and five carbon atoms. Includes compounds that are derived from quinolines.

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1

eMolecules​ 5-HYDROXYQUINOLINE-3-CARBOXYLIC ACID | 911108-90-2 | MFCD18417133 | 1g

AstaTech | 5-HYDROXYQUINOLINE-3-CARBOXYLIC ACID | 1g | 200618597 | 80318 | 95.000 | 911108-90-2 | MFCD18417133 | 189.170 | C10H7NO3

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2

Medchemexpress LLC Racemic equol | 94105-90-5 | MFCD00016662 | 99.6% | 242.27 g·mol⁻¹ | C15H14O3 | 200 MG
SDP

Racemic equol is the racemate of equol, a nonsteroidal estrogen receptor ligand and a metabolite of the soy isoflavones daidzin and daidzein. It is commonly used in research on estrogen receptor pharmacology and isoflavone metabolism, with reported EC50 values of 200 nM for ERα and 74 nM for ERβ.

  • Racemic mixture of equol suitable for receptor biology studies.
  • Shows EC50s of 200 nM (ERα) and 74 nM (ERβ).
  • Molecular weight 242.27 g·mol⁻¹ and formula C15H14O3.
  • High purity (≈99.6%) for consistent experimental results.
  • Solid powder form, stable when stored at low temperatures.
  • Available in multiple pack sizes from milligram to gram quantities.

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3

Apexbio Technology LLC AM966 1228690-19-4 200mg
SDP

AM966 (CAS 1228690-19-4) is an orally bioavailable small-molecule antagonist that selectively targets Lysophosphatidic acid type 1 receptor (LPA1) AM966 exhibits potent inhibitory activity against LPA1 receptors from humans and mice with IC50 values of approximately 17 nM and 19 nM respectively demonstrating selectivity over other LPA receptor subtypes (LPA2 5) In vitro AM966 blocks LPA-mediated chemotactic responses in IMR-90 human lung fibroblasts A2058 human melanoma cells and CHO cell lines In vivo AM966 effectively attenuates lung fibrosis inflammation and associated weight loss in bleomycin-induced murine pulmonary fibrosis models highlighting its utility in research on fibrotic diseases

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4

Medchemexpress LLC Teniposide | 29767-20-2 | MFCD00866516 | 98.4% | 656.65 | 200 MG
SDP

Teniposide is a podophyllotoxin derivative that functions as a topoisomerase II inhibitor and is used as a chemotherapeutic agent.

  • Acts as a topoisomerase II inhibitor
  • Functions as a chemotherapeutic agent
  • Demonstrates antiproliferative activity against various human cancer cell lines, including A549, CWR22R, HeLa, HepG2, MCF7, PC-3, and RPMI 8402
  • Induces apoptosis in Tca8113 cells
  • Causes cell cycle arrest at the G2/M phase in Tca8113 cells
  • Can be formulated into a clear solution for in vivo experiments using various protocols, including 10% DMSO, 40% PEG300, 5% Tween-80, and 45% Saline, or 10% DMSO and 90% Corn Oil
  • Referenced in multiple publications

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