Quinolines and derivatives
Apexbio Technology LLC Phenanthrene 85-01-8 200mg
Phenanthrene is a polycyclic aromatic hydrocarbon (PAH) that exerts its biological activity primarily through the induction of cellular inflammatory responses enhancement of reactive oxygen species (ROS) generation and activation of apoptotic signaling pathways Based on these pharmacological properties phenanthrene is utilized in research to study PAH-induced cellular toxicity oxidative stress mechanisms and programmed cell death pathways Additionally it serves as a representative analyte in environmental toxicology investigations to detect quantify and evaluate PAH contamination in water and soil supporting the development of toxicological evaluation models and detection methods
Sigma Aldrich Fine Chemicals Biosciences Chlorohydroquinone technical grade, 85% | Purity: 85% | Mol Wt: 144.56 | 615-67-8 | MFCD00002341 | 100G
Chlorohydroquinone technical grade, 85% | Purity: 85% | Mol Wt: 144.56 | 615-67-8 | MFCD00002341 | 100G
Apexbio Technology LLC KY 02111 1118807-13-8 200mg
KY 02111 (CAS 1118807-13-8) is a selective inhibitor of the Wnt signaling pathway acting downstream of GSK3 and APC within the -catenin destruction complex By modulating canonical Wnt signaling KY 02111 has been shown to significantly reduce luciferase reporter activity in IMR90-1 human induced pluripotent stem cells (hiPSCs) transfected with a TCF-responsive plasmid in a dose-dependent manner When applied to differentiating cardiac cell colonies KY 02111 induces the expression of cardiac-specific markers in approximately 73 85% of IMR90-1 hiPSCs by day 30 This compound is valuable for investigating Wnt-mediated cellular processes and optimizing protocols for directed differentiation of pluripotent stem cells