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Quinolines and derivatives

Aromatic organic heterocyclic compounds that contain a benzene ring fused with a six-membered ring that contains one nitrogen atom and five carbon atoms. Includes compounds that are derived from quinolines.

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1

Apexbio Technology LLC Levodopa 59-92-7 200mg
SDP

Levodopa (59-92-7) is a small-molecule precursor of dopamine It modulates dopaminergic signaling pathways thereby influencing neurotransmission and associated neuronal functions Levodopa exerts its biological activity primarily through enzymatic decarboxylation by aromatic L-amino acid decarboxylase within dopaminergic neurons yielding dopamine In in vitro assays levodopa demonstrates cholinergic receptor antagonism with reported IC50 values typically ranging 10 30 M depending on specific cellular and experimental conditions Based on these pharmacological properties levodopa holds research potential in studies of dopaminergic signaling neuronal plasticity motor function modulation preclinical Parkinson s disease models and stroke recovery investigations

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2

Apexbio Technology LLC Trimethobenzamide hydrochloride 554-92-7 200mg
SDP

Trimethobenzamide hydrochloride is a dopamine D2 receptor antagonist frequently utilized in biomedical research investigating mechanisms underlying emesis and anti-emetic responses The compound exerts pharmacological effects by inhibiting dopamine receptor-mediated neurotransmission within the chemoreceptor trigger zone (CTZ) of the central nervous system a key regulatory area implicated in nausea and vomiting reflexes Through selective receptor blockade trimethobenzamide hydrochloride allows researchers to elucidate dopamine-dependent molecular and physiological pathways contributing to vomiting in experimental animal models This compound is commonly applied in laboratory settings to characterize the pharmacodynamic profiles of novel anti-emetic agents and to evaluate dopamine receptor-involved emetic signaling The reported IC50 value for dopamine D2 receptor inhibition is approximately 320 nM

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3

Medchemexpress LLC Trimethobenzamide hydrochloride | 554-92-7 | 99.9% | 200 MG
SDP

Trimethobenzamide hydrochloride is a non-phenothiazine benzamide antiemetic that acts centrally to block D2 receptors. It inhibits the medullary chemoreceptor trigger zone, blocking emetic impulses to prevent nausea and vomiting.

  • Acts as a blocker of the D2 receptor
  • Used to prevent nausea and vomiting
  • Exhibits 60% to 100% oral bioavailability
  • Achieves peak effect approximately 45 minutes after oral administration
  • Achieves peak effect approximately 30 minutes after intramuscular administration

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4

eMolecules​ 7-Bromo-4-hydroxyquinoline-3-carboxylic acid | 860205-92-1 | MFCD02684222 | 1g

Apollo Scientific | 7-Bromo-4-hydroxyquinoline-3-carboxylic acid | 1g | 562462421 | OR183473 | | 860205-92-1 | MFCD02684222 | 268.066 | C10H6BrNO3

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5

Medchemexpress LLC Sulfo-N-succinimidyl 4-maleimidobutyrate sodium salt | 185332-92-7 | MFCD17215919 | 98.8% | 382.28 g/mol | C12H11N2NaO9S | 1 ML
SDP

Sulfo-GMBS is a water-soluble, heterobifunctional cross-linker that links primary amines to sulfhydryl groups via a non-cleavable maleimide spacer. Supplied as a ready-to-use 10 mM solution in DMSO or as a solid, it is intended for protein and peptide conjugation, immobilization, and labeling in biochemical and assay workflows.

  • Water-soluble amine-thiol cross-linker suitable for protein and peptide conjugation.
  • Provides a short, non-cleavable spacer facilitating stable linkage between functional groups.
  • Available as a 10 mM solution in DMSO or in solid form for flexible use.
  • High purity (approximately 98.8%) supports reproducible conjugation reactions.
  • Soluble in DMSO at 50 mg/mL (≈130.8 mM) for easy preparation of working solutions.
  • Recommended storage: solid at -20°C sealed; in solvent at -80°C for extended stability.

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6

Medchemexpress LLC Sulfo-N-succinimidyl 4-maleimidobutyrate sodium salt | 185332-92-7 | MFCD17215919 | 98.8% | 382.28 g/mol | C12H11N2NaO9S | 10 MG
SDP

Sulfo-GMBS is a water-soluble, heterobifunctional cross-linking reagent containing a sulfo-NHS ester and a maleimide. It enables selective conjugation between primary amines and sulfhydryl groups in aqueous systems, making it suitable for protein and peptide bioconjugation, surface immobilization, and analytical assay development.

  • Water-soluble heterobifunctional cross-linker for aqueous reactions.
  • Reacts with primary amines via sulfo-NHS ester chemistry.
  • Reacts with sulfhydryl groups via maleimide chemistry.
  • Suitable for protein and peptide conjugation and surface immobilization.
  • Provided in small solid quantities for laboratory-scale use.
  • High purity for consistent conjugation performance.

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7

eMolecules​ ChemScene / 5-(Chloromethyl)-2-(difluoromethoxy)pyridine / 100mg / 714107173 / CS-W022256 / 0.000 / 1211584-92-7 / MFCD18261898 / 193.580 / C7H6ClF2NO

ChemScene / 5-(Chloromethyl)-2-(difluoromethoxy)pyridine / 100mg / 714107173 / CS-W022256 / 0.000 / 1211584-92-7 / MFCD18261898 / 193.580 / C7H6ClF2NO

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8

Medchemexpress LLC 3-(N-maleimido-propionylamino)-propyl-sulfonic acid sodium salt | 185332-92-7 | MFCD17215919 | 98.8% | 382.28 g·mol⁻¹ | C12H11N2NaO9S | 25 MG
SDP

Sulfo-GMBS is a water-soluble, heterobifunctional cross-linker bearing a sulfo-NHS ester reactive toward primary amines and a maleimide reactive toward sulfhydryl groups. It enables efficient amine-to-thiol conjugation in aqueous buffers for protein and peptide modification, labeling, and cross-linking workflows. The sodium sulfonate improves aqueous solubility for biological applications.

  • Water-soluble heterobifunctional cross-linker for amine-to-thiol coupling
  • Contains a sulfo-NHS ester reactive toward primary amines
  • Contains a maleimide group selective for sulfhydryl groups
  • Suitable for conjugation in aqueous buffers and physiological conditions
  • High purity supports consistent conjugation performance
  • Applicable to protein labeling, cross-linking, and bioconjugation assays

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9

Accela Chembio Inc Spiro[1 | 2 | 3 | 4-tetrahydroquinazoline-2 | 1'-cyclobutane]-4-one | 5g | 1363165-92-7 | MFCD21641327 | 97+% | Shelf Life: 1260 Days | Light Sensitive/moisture Sensitive/+4
SDP

Spiro[1 | 2 | 3 | 4-tetrahydroquinazoline-2 | 1'-cyclobutane]-4-one | 5g | 1363165-92-7 | MFCD21641327 | 97+% | Shelf Life: 1260 Days | Light Sensitive/moisture Sensitive/+4

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10

Accela Chembio Inc Spiro[1 | 2 | 3 | 4-tetrahydroquinazoline-2 | 1'-cyclobutane]-4-one | 25g | 1363165-92-7 | MFCD21641327 | 97+% | Shelf Life: 1260 Days | Light Sensitive/moisture Sensitive/+4
SDP

Spiro[1 | 2 | 3 | 4-tetrahydroquinazoline-2 | 1'-cyclobutane]-4-one | 25g | 1363165-92-7 | MFCD21641327 | 97+% | Shelf Life: 1260 Days | Light Sensitive/moisture Sensitive/+4

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