Tetrapyrroles and derivatives
Apexbio Technology LLC Chlorin e6(Synonyms: Ce6, Chlorophyllin e6, Chlorophyll derivative e6, Chlorin-e6, Chlorin e-6), 100mg, CAS: 19660-77-6.
Chlorin e6 (Ce6 CAS 19660-77-6) is a second-generation photosensitizer utilized in photodynamic therapy (PDT) research with demonstrated anticancer activity when activated by laser irradiation Upon irradiation Ce6 generates reactive oxygen species mediating cytotoxic effects and cellular apoptosis In mouse models intravenous administration of Ce6 (2 5 10 mg/kg) combined with irradiation (50 200 J/cm ) resulted in complete elimination of implanted fibrosarcomas In clinical trials for bronchogenic superficial squamous cell carcinoma Ce6-based PDT (40 mg/m 100 J/cm ) produced complete response rates up to 82 9% underscoring its utility for cancer therapy studies
Medchemexpress LLC Chlorin e6 trisodium | 72984-36-2 | 98.7% | 662.62 | C34H33N4Na3O6 | 5mg
Chlorin e6 Ce6 (trisodium) is a water-soluble derivative of chlorophyll belonging to the chlorin class of photosensitizers with an absorption wavelength range of 600-670 nm Chlorin e6 trisodium emits characteristic red fluorescence upon light excitation enabling real-time identification of tumor boundaries and progression Chlorin e6 trisodium can be used for the study of photodynamic therapy (PDT) of cancers (bladder cancer) and fluorescence diagnosis of neoplastic lesions[1][2][3]
Frontier Specialty Chemicals 100mg 5-Mono(4-carboxyphenyl)-10,15,20-triphenyl porphine, 95051-10-8 MFCD01366156
5-Mono(4-carboxyphenyl)-10,15,20-triphenyl porphine CAS: 95051-10-8 MFCD01366156 Porphyrins Synthetic Porphyrins
![Chemscene ChemScene | 3-Oxobenzo[d]isothiazole-2(3H)-carbaldehyde 1,1-dioxide | 5G | CS-0106913 | 0.98 | 50978-45-5| MFCD23380208 | 211.2](https://assets.fishersci.com/TFS-Assets/CCG/product-images/CS-0106913.JPG-250.jpg)
Chemscene ChemScene | 3-Oxobenzo[d]isothiazole-2(3H)-carbaldehyde 1,1-dioxide | 5G | CS-0106913 | 0.98 | 50978-45-5| MFCD23380208 | 211.2
ChemScene | 3-Oxobenzo[d]isothiazole-2(3H)-carbaldehyde 1,1-dioxide | 5G | CS-0106913 | 0.98 | 50978-45-5| MFCD23380208 | 211.2
Frontier Specialty Chemicals 5g meso-Tetra(4-carboxyphenyl)porphine, 14609-54-2 MFCD00064860
meso-Tetra(4-carboxyphenyl)porphinemeso-Tetraphenylporphine- 4,4',4'',4'''-tetracarboxylic acid CAS: 14609-54-2 MFCD00064860 Porphyrins Synthetic Porphyrins
Cayman Chemical Mn III ProtoporphyrIn IX Chl
A metalloporphyrin; induces mRNA expression of the genes encoding δ-aminolevulinate synthase and HO in chick embryo liver cells at 10 µM; manganese(III) protoporphyrin IX chloride-containing nanobialys have been used in MRI of fibrin clots in vitro; has been used in the synthesis of MnGGH
Medchemexpress LLC Protoporphyrin IX (Standard) | 553-12-8 | 96.1% | 50 MG
Protoporphyrin IX (Standard) serves as an analytical reference standard for diverse research and analytical applications. It functions as a key intermediate in the heme biosynthetic pathway, acting as both a radiation sensitizer-boosting reactive oxygen species (ROS) generation and inducing DNA damage even in hypoxic states-and a photosensitizer, undergoing photobleaching upon light exposure.
- Enhances ROS generation and induces DNA damage.
- Undergoes photobleaching through direct degradation by light irradiation.
- Accumulates in tumor cells after 5-aminolevulinic acid (5-ALA) administration.
- Causes selective improvement of basal cell carcinoma when activated by red fluorescence.
- Promising for research into sonodynamic and photodynamic agents for various cancers.
- Used in qualitative, quantitative, and methodological research experiments.
- Ideal for applications in HPLC, GC, and MS.
Apexbio Technology LLC Bilirubin 635-65-4 10mM (in 1mL DMSO)
Bilirubin (CAS 635-65-4) is a bile pigment naturally produced from the catabolism of heme It exhibits antioxidant properties primarily via scavenging reactive oxygen species and inhibiting oxidative modification of biomolecules Bilirubin modulates signaling pathways associated with inflammation oxidative stress and cellular apoptosis rendering it relevant in biomedical research focused on hepatic disorders cardiovascular disease and neurodegenerative conditions Originally identified from bezoar bilirubin requires storage under airtight cool and dry conditions to maintain stability
Sigma Aldrich Fine Chemicals Biosciences SIGMA ALDRICH FINE CHEMICALS BIOSCIENCES
NC4013060 CYANOCOBALAMIN
