Tetrapyrroles and derivatives
Abcam Monosodium urate (PBS solution), NLRP3/NALP3 inflammasome activator, 10MG
MW 190.09 Da. NLRP3/NALP3 inflammasome activator. Stimulates caspase-1 activating NLRP3/NALP3 inflammasome, results in active IL-1β and IL-18 production. Active in vitro and in vivo.
The product is subject to the following: Abcam Restricted Use Statement
Abcam PDTC (Ammonium pyrrolidinedithiocarbamate), NF-kappaB inhibitor antio x idant, 100MG
MW 164.3 Da. Selective NF-κB inhibitor. Inhibits translation of nitric oxide synthase mRNA to prevent induction. Metal ion chelator and antioxidant. Active in vitro.
The product is subject to the following: Abcam Restricted Use Statement
Sigma Aldrich Fine Chemicals Biosciences Vitamin B12 | 68-19-9 | MFCD00151092 | 100mg
Vitamin B12 | Purity: ≥98% | MW:1355.37 | 68-19-9 | MFCD00151092 | 100mg
Abcam BIM 23056, Somatostatin receptor 5 (sst5) antagonist, 1MG
MW 1232.5 Da. BIM 23056, Somatostatin receptor 5 (sst5) antagonist. Achieve your results faster with highly validated, pure and trusted compounds.
The product is subject to the following: Abcam Restricted Use Statement
Abcam SB 505124, ALK5 inhibitor, 25MG
MW 335.4 Da, Purity >98%. Potent, reversible, competitive ALK5 inhibitor (IC₅₀ values are 47 and 129 nM for ALK5 and ALK4 respectively). Inhibits ALK7 but not ALK1, 2, 3, or 6. Shows antifibrotic effects in vivo. .
The product is subject to the following: Abcam Restricted Use Statement
Abcam (S)-(-)-Raclopride, D2 receptor antagonist, 10MG
MW 347.24 g/mol, Purity >97%. High affinity (Kd = 1.2 nM) and high selectivity for D₂ receptors in vitro and in vivo (IC₅₀ = 32 nM). Centrally active following systemic administration.
The product is subject to the following: Abcam Restricted Use Statement
Abcam CK 666, Actin polymerization inhibitor, 50MG
MW 296.3 Da, Purity >99%. Potent inhibitor of actin polymerization. Inhibits the Arp2/3 (IC₅₀ = 17 μM), SpArp2/3 (IC₅₀ = 5 μM) and HsArp2/3 complexes (IC₅₀= 4 μM) by preventing a shift into an active conformation.
The product is subject to the following: Abcam Restricted Use Statement
Sigma Aldrich Fine Chemicals Biosciences Hemin from bovine, >=90% | 16009-13-5 | MFCD00010726 | 10G
Hemin from bovine, >=90% | Purity: >=90% | Mol Wt: 651.94 | 16009-13-5 | MFCD00010726 | 10G
Abcam SB 203580, p38 MAPK inhibitor, 500UG
MW 377.4 Da, Purity >99%. SB 203580, p38 MAPK inhibitor. Achieve your results faster with highly validated, pure and trusted compounds.
The product is subject to the following: Abcam Restricted Use Statement
Abcam 4-Thiouridine, RNA synthesis inhibitor, 100MG
MW 260.27 Da, Purity >99%. Ribonucleoside (Uridine ab143255) analog. Antisense agent. RNA synthesis inhibitor. Modifies oligos slated for RNA. Induces p53 and inhibits proliferation. Metabolically labels RNA for stability studies.
The product is subject to the following: Abcam Restricted Use Statement
Abcam CL-316243 disodium salt, adrenergic-beta3 receptor agonist, 5MG
MW 465.8 Da, Purity >99%. Selective adrenergic-β3 receptor agonist. Induces adipose tissue remodelling in rat. Hypoglycemic agent. Active *in vivo* and *in vitro*.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Clozapine N-o x ide, Metabolite of Clozapine, 100MG
MW 342.8 Da, Purity >99%. Metabolite of atypical antipsychotic Clozapine (ab120019). Active in vitro and in vivo.
The product is subject to the following: Abcam Restricted Use Statement
Abcam SEN 12333, alpha7 nicotinic acetylcholine receptor (nAChR) agonist, 50MG
MW 339.4 Da, Purity >98%. Potent, selective α7 nicotinic acetylcholine receptor (nAChR) agonist. High affinity for rat α7 receptors (Ki = 260 nM). Full agonist in functional Ca²+ flux studies (EC₅₀ = 1.6 μM). Active in vivo and in vitro. Excellent brain penetration. Orally bioavailable.
The product is subject to the following: Abcam Restricted Use Statement
Abcam ODQ, NO-sensitive guanylyl cyclase inhibitor, 10MG
MW 187.15 Da, Purity >99%. Selective, potent inhibitor of nitric oxide-sensitive guanylyl cyclase. Achieve your results faster with highly validated, pure and trusted compounds.
The product is subject to the following: Abcam Restricted Use Statement
Abcam (R,S)-CPP, NMDA antagonist, 10MG
MW 252.2 Da. Potent, competitive NMDA antagonist. See separate isomer (ab120159). Also available in simple stock solutions (ab146720) - add 1 ml of water to get an exact, ready-to-use concentration.
The product is subject to the following: Abcam Restricted Use Statement