Thiolactams
Medchemexpress LLC 4-Thiouracil | 591-28-6 | 99.98% | 128.15 | 100 MG
4-Thiouracil is a thionucleobase possessing cytostatic properties. It functions as a biological photoprobe for detecting RNA structures and nucleic acid-nucleic acid contacts. Additionally, it serves as a potent ultraviolet A (UVA) photosensitizer, generating reactive oxygen species (O2). 4-Thiouracil holds promise for research in photocrosslinking, photodamage, and photodynamic therapy.
- Thionucleobase with cytostatic properties.
- Can be used as biological photoprobes to detect RNA structures and nucleic acid-nucleic acid contacts.
- Acts as a strong UVA photosensitizer, providing a source of reactive oxygen species (O2).
- Promising for research in photocrosslinking, photodamage, and photodynamic therapy.
Apexbio Technology LLC 2-Thiouracil 141-90-2 10mM (in 1mL DMSO)
2-Thiouracil (CAS 141-90-2) is a sulfur-containing derivative of uracil that functions as an inhibitor of thyroid hormone synthesis It exerts its antihyperthyroid effects by interfering with the enzymatic iodination of tyrosine residues within thyroglobulin thereby suppressing the production of triiodothyronine (T3) and thyroxine (T4) Due to its capacity to modulate thyroid function 2-Thiouracil is utilized in biomedical research to study thyroid hormone regulation and associated disorders as well as to model hypothyroid states in experimental settings
Medchemexpress LLC 4-thiouridine 5′-triphosphate tetralithium | 20188-72-1 | C9H11Li4N2O14P3S | 5 MG
4-Thiouridine 5′-triphosphate tetralithium (4-Thio-UTP) is a UTP analog and a potent P2Y2 and P2Y4 receptor agonist, with EC50 values of 35 nM for hP2Y2 and 350 nM for hP2Y4. This compound is a light yellow to yellow solid suitable for various research applications.
- UTP analog
- Potent P2Y2 and P2Y4 receptor agonist
- Suitable for cross-linking experiments
- Suitable for transcriptional complex labeling studies
- Ships at room temperature in the continental US
- Store at 4°C, sealed, away from moisture and light
- For research use only
Cayman Chemical 4-ThIouracIl 1g
A site-specific, photoactivatable probe used to detect RNA structures and nucleic acid-nucleic acid contacts
Medchemexpress LLC 4-Thiouracil | 591-28-6 | 99.98% | 128.15 | 250 MG
4-Thiouracil is a thionucleobase with cytostatic properties. It can be utilized as a biological photoprobe to detect RNA structures and nucleic acid-nucleic acid contacts. Additionally, it functions as a strong ultraviolet A (UVA) photosensitizer, serving as a source of reactive oxygen species (O2). 4-Thiouracil shows promise for research in photocrosslinking, photodamage, and photodynamic therapy.
- Thionucleobase with cytostatic properties
- Can be used as biological photoprobes to detect RNA structures and nucleic acid-nucleic acid contacts
- Acts as a strong ultraviolet A (UVA) photosensitizer
- Provides a source of reactive oxygen species of O2
- Promising for research of photocrosslinking, photodamage, and photodynamic therapy
Medchemexpress LLC 4-Thiouridine | 13957-31-8 | 100.0% | 260.27 | 5 MG
4-Thiouridine is a ribonucleoside analog widely used in RNA analysis and (m)RNA labeling. It inhibits rRNA synthesis and causes a nucleolar stress response.
- Ribonucleoside analog
- Used in RNA analysis and (m)RNA labeling
- Inhibits rRNA synthesis
- Causes a nucleolar stress response
- At 0-10 μM, it labels and purifies nascent rRNA without significantly affecting rRNA synthesis
- At ≥50 μM, it strongly inhibits production and processing of rRNA
Medchemexpress LLC 4-Thiouridine | 13957-31-8 | 99.98% | 260.27 | 25 MG
4-Thiouridine is a ribonucleoside analog, widely used in RNA analysis and (m)RNA labeling. It inhibits rRNA synthesis and causes a nucleolar stress response.
- Functions as a ribonucleoside analog.
- Utilized for RNA analysis and (m)RNA labeling.
- Labels and purifies nascent rRNA at concentrations of 0-10 μM without significantly affecting rRNA synthesis.
- Strongly inhibits the production and processing of rRNA at concentrations of ≥50 μM.
- Targets nucleoside antimetabolite/analog.
- Acts on the cell cycle/DNA damage pathway.
Medchemexpress LLC Uridine,4-thio- | 13957-31-8 | 99.98% | 260.27 | 1 ML
4-Thiouridine is a ribonucleoside analog widely used in RNA analysis and (m)RNA labeling. It works by inhibiting rRNA synthesis, which leads to a nucleolar stress response. It is intended for research use only and is not sold to patients.
- Ribonucleoside analog
- Used in RNA analysis and mRNA labeling
- Inhibits rRNA synthesis
- Causes a nucleolar stress response
- High purity: 99.98%
- Labels and purifies nascent rRNA at 0-10 μM
- Strongly inhibits rRNA production and processing at ≥50 μM
Selleck Chemical LLC 4-Thiouridine-E1292-1G
4-thiouridine (4-Thio-UTP) a thiouridine and a nucleoside analogue has a role as an affinity label and an antimetabolite
Cayman Chemical 4-ThIouracIl 500mg
A site-specific, photoactivatable probe used to detect RNA structures and nucleic acid-nucleic acid contacts
Selleck Chemical LLC 4-Thiouridine-E1292-25MG
4-thiouridine (4-Thio-UTP) a thiouridine and a nucleoside analogue has a role as an affinity label and an antimetabolite
Medchemexpress LLC 2-Thiouracil | 141-90-2 | 99.9% | 5 G
2-Thiouracil (Thiouracil) is a selective neuronal nitric oxide synthase (nNOS) inhibitor with a Ki value of 20 μM. It antagonizes BH4-induced nNOS dimerization and has been observed to stimulate the growth of pea and corn root segments. Additionally, it functions as an antithyroid compound and a highly specific melanoma detector.
- Functions as a selective neuronal nitric oxide synthase (nNOS) inhibitor
- Antagonizes BH4-induced nNOS dimerization
- Acts as an antithyroid compound
- Serves as a highly specific melanoma detector
- Stimulates growth of pea and corn root segments
Medchemexpress LLC 2-Thiouracil | 141-90-2 | 99.91% | 100 G
2-Thiouracil acts as a selective inhibitor for neuronal nitric oxide synthase (nNOS) with a Ki value of 20 μM, and it also counteracts BH4-induced nNOS dimerization. Additionally, it functions as an antithyroid agent and a highly specific detector for melanoma. This compound has also been observed to stimulate the growth of root segments in pea and corn plants.
- Selective inhibitor of neuronal nitric oxide synthase (nNOS).
- Antagonizes BH4-induced nNOS dimerization.
- Functions as an antithyroid compound.
- Highly specific detector for melanoma.
- Stimulates root growth in pea and corn.