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2-Thiouracil is a selective neuronal nitric oxide synthase (nNOS) inhibitor with a Ki value of 20 μM. It antagonizes BH4-induced nNOS dimerization and is also known as an antithyroid compound and a highly specific melanoma detector. It has been shown to stimulate the growth of pea and corn root segments.
Significantly reduces the number of nNOS dimers
Inhibits conventional oligomerization of indole
Generates new major products including DHI-TU adducts
Stimulates root growth in pea and corn roots
Rapidly incorporates into tumor pigment in melanoma-bearing mice
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
2-Thiouracil is a selective neuronal nitric oxide synthase (nNOS) inhibitor. It antagonizes BH4-induced nNOS dimerization and acts as an antithyroid compound. This compound also functions as a highly specific melanoma detector and stimulates the growth of pea and corn root segments.