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Thiolactams

Organic heterocyclic compounds that contain a cyclic thioamide; they are analogous to lactams with the oxygen atom replaced by a sulfur atom.
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1

4-Thiouridine, ∽98, MP Biomedicals™

CAS: 13957-31-8 Molecular Formula: C9H12N2O5S Molecular Weight (g/mol): 260.26 MDL Number: MFCD00006538 InChI Key: ZLOIGESWDJYCTF-XVFCMESISA-N Synonym: 4-thiouridine,thiouridine,uridine, 4-thio,1-beta-d-ribofuranosyl-4-thiouracil,1-2r,3r,4s,5r-3,4-dihydroxy-5-hydroxymethyl tetrahydrofuran-2-yl-4-thioxo-3,4-dihydropyrimidin-2 1h-one,1-beta-d-ribofuranosyl-4-thioxo-3,4-dihydropyrimidin-2 1h-one,s4u,thiouridine van,uridine,4-thio,4-thio-d-uridine PubChem CID: 3032615 ChEBI: CHEBI:20480 IUPAC Name: 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-sulfanylidene-1,2,3,4-tetrahydropyrimidin-2-one SMILES: OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=CC(=S)NC1=O

PubChem CID 3032615
CAS 13957-31-8
Molecular Weight (g/mol) 260.26
ChEBI CHEBI:20480
MDL Number MFCD00006538
SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=CC(=S)NC1=O
Synonym 4-thiouridine,thiouridine,uridine, 4-thio,1-beta-d-ribofuranosyl-4-thiouracil,1-2r,3r,4s,5r-3,4-dihydroxy-5-hydroxymethyl tetrahydrofuran-2-yl-4-thioxo-3,4-dihydropyrimidin-2 1h-one,1-beta-d-ribofuranosyl-4-thioxo-3,4-dihydropyrimidin-2 1h-one,s4u,thiouridine van,uridine,4-thio,4-thio-d-uridine
IUPAC Name 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-sulfanylidene-1,2,3,4-tetrahydropyrimidin-2-one
InChI Key ZLOIGESWDJYCTF-XVFCMESISA-N
Molecular Formula C9H12N2O5S
2

4-Thiouridine, 98+%

CAS: 13957-31-8 Molecular Formula: C9H12N2O5S Molecular Weight (g/mol): 260.26 MDL Number: MFCD00006538 InChI Key: ZLOIGESWDJYCTF-XVFCMESISA-N PubChem CID: 3032615 ChEBI: CHEBI:20480 SMILES: OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=CC(=S)NC1=O

PubChem CID 3032615
CAS 13957-31-8
Molecular Weight (g/mol) 260.26
ChEBI CHEBI:20480
MDL Number MFCD00006538
SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=CC(=S)NC1=O
InChI Key ZLOIGESWDJYCTF-XVFCMESISA-N
Molecular Formula C9H12N2O5S
3

4-Thiouridine, MP Biomedicals™

CAS: 13957-31-8 Molecular Formula: C9H12N2O5S Molecular Weight (g/mol): 260.26 MDL Number: MFCD00006538 InChI Key: ZLOIGESWDJYCTF-XVFCMESISA-N Synonym: 4-thiouridine,thiouridine,uridine, 4-thio,1-beta-d-ribofuranosyl-4-thiouracil,1-2r,3r,4s,5r-3,4-dihydroxy-5-hydroxymethyl tetrahydrofuran-2-yl-4-thioxo-3,4-dihydropyrimidin-2 1h-one,1-beta-d-ribofuranosyl-4-thioxo-3,4-dihydropyrimidin-2 1h-one,s4u,thiouridine van,uridine,4-thio,4-thio-d-uridine PubChem CID: 3032615 ChEBI: CHEBI:20480 IUPAC Name: 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-sulfanylidene-1,2,3,4-tetrahydropyrimidin-2-one SMILES: OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=CC(=S)NC1=O

PubChem CID 3032615
CAS 13957-31-8
Molecular Weight (g/mol) 260.26
ChEBI CHEBI:20480
MDL Number MFCD00006538
SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=CC(=S)NC1=O
Synonym 4-thiouridine,thiouridine,uridine, 4-thio,1-beta-d-ribofuranosyl-4-thiouracil,1-2r,3r,4s,5r-3,4-dihydroxy-5-hydroxymethyl tetrahydrofuran-2-yl-4-thioxo-3,4-dihydropyrimidin-2 1h-one,1-beta-d-ribofuranosyl-4-thioxo-3,4-dihydropyrimidin-2 1h-one,s4u,thiouridine van,uridine,4-thio,4-thio-d-uridine
IUPAC Name 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-sulfanylidene-1,2,3,4-tetrahydropyrimidin-2-one
InChI Key ZLOIGESWDJYCTF-XVFCMESISA-N
Molecular Formula C9H12N2O5S
4

4-Thiouracil, 97%, Thermo Scientific Chemicals

CAS: 591-28-6 Molecular Formula: C4H4N2OS Molecular Weight (g/mol): 128.15 MDL Number: MFCD00090842 InChI Key: OVONXEQGWXGFJD-UHFFFAOYSA-N Synonym: 4-thiouracil,2-hydroxy-4 1h-pyrimidinethione,4-thioxo-3,4-dihydropyrimidin-2 1h-one,2-hydroxy-4-mercaptopyrimidine,uracil, 4-thio,4-mercaptopyrimidin-2-ol,4-sulfanylpyrimidin-2-ol,2-hydroxy-4-thiopyrimidine,2 1h-pyrimidinone, 3,4-dihydro-4-thioxo,2 1h-pyrimidinone, 4-mercapto-9ci PubChem CID: 2734394 IUPAC Name: 4-sulfanylidene-1,2,3,4-tetrahydropyrimidin-2-one SMILES: O=C1NC=CC(=S)N1

PubChem CID 2734394
CAS 591-28-6
Molecular Weight (g/mol) 128.15
MDL Number MFCD00090842
SMILES O=C1NC=CC(=S)N1
Synonym 4-thiouracil,2-hydroxy-4 1h-pyrimidinethione,4-thioxo-3,4-dihydropyrimidin-2 1h-one,2-hydroxy-4-mercaptopyrimidine,uracil, 4-thio,4-mercaptopyrimidin-2-ol,4-sulfanylpyrimidin-2-ol,2-hydroxy-4-thiopyrimidine,2 1h-pyrimidinone, 3,4-dihydro-4-thioxo,2 1h-pyrimidinone, 4-mercapto-9ci
IUPAC Name 4-sulfanylidene-1,2,3,4-tetrahydropyrimidin-2-one
InChI Key OVONXEQGWXGFJD-UHFFFAOYSA-N
Molecular Formula C4H4N2OS
5

Thermo Scientific Chemicals 4-Thiouracil, 97%

CAS: 591-28-6 Molecular Formula: C4H4N2OS Molecular Weight (g/mol): 128.15 MDL Number: MFCD00090842 InChI Key: OVONXEQGWXGFJD-UHFFFAOYSA-N Synonym: 4-thiouracil,2-hydroxy-4 1h-pyrimidinethione,4-thioxo-3,4-dihydropyrimidin-2 1h-one,2-hydroxy-4-mercaptopyrimidine,uracil, 4-thio,4-mercaptopyrimidin-2-ol,4-sulfanylpyrimidin-2-ol,2-hydroxy-4-thiopyrimidine,2 1h-pyrimidinone, 3,4-dihydro-4-thioxo,2 1h-pyrimidinone, 4-mercapto-9ci PubChem CID: 2734394 IUPAC Name: 4-sulfanylidene-1H-pyrimidin-2-one SMILES: O=C1NC=CC(=S)N1

PubChem CID 2734394
CAS 591-28-6
Molecular Weight (g/mol) 128.15
MDL Number MFCD00090842
SMILES O=C1NC=CC(=S)N1
Synonym 4-thiouracil,2-hydroxy-4 1h-pyrimidinethione,4-thioxo-3,4-dihydropyrimidin-2 1h-one,2-hydroxy-4-mercaptopyrimidine,uracil, 4-thio,4-mercaptopyrimidin-2-ol,4-sulfanylpyrimidin-2-ol,2-hydroxy-4-thiopyrimidine,2 1h-pyrimidinone, 3,4-dihydro-4-thioxo,2 1h-pyrimidinone, 4-mercapto-9ci
IUPAC Name 4-sulfanylidene-1H-pyrimidin-2-one
InChI Key OVONXEQGWXGFJD-UHFFFAOYSA-N
Molecular Formula C4H4N2OS
6

4-Thiouracil 97.0+%, TCI America™

CAS: 591-28-6 Molecular Formula: C4H4N2OS Molecular Weight (g/mol): 128.15 MDL Number: MFCD00090842 InChI Key: OVONXEQGWXGFJD-UHFFFAOYSA-N Synonym: 4-thiouracil,2-hydroxy-4 1h-pyrimidinethione,4-thioxo-3,4-dihydropyrimidin-2 1h-one,2-hydroxy-4-mercaptopyrimidine,uracil, 4-thio,4-mercaptopyrimidin-2-ol,4-sulfanylpyrimidin-2-ol,2-hydroxy-4-thiopyrimidine,2 1h-pyrimidinone, 3,4-dihydro-4-thioxo,2 1h-pyrimidinone, 4-mercapto-9ci PubChem CID: 2734394 IUPAC Name: 4-sulfanylidene-1,2,3,4-tetrahydropyrimidin-2-one SMILES: O=C1NC=CC(=S)N1

PubChem CID 2734394
CAS 591-28-6
Molecular Weight (g/mol) 128.15
MDL Number MFCD00090842
SMILES O=C1NC=CC(=S)N1
Synonym 4-thiouracil,2-hydroxy-4 1h-pyrimidinethione,4-thioxo-3,4-dihydropyrimidin-2 1h-one,2-hydroxy-4-mercaptopyrimidine,uracil, 4-thio,4-mercaptopyrimidin-2-ol,4-sulfanylpyrimidin-2-ol,2-hydroxy-4-thiopyrimidine,2 1h-pyrimidinone, 3,4-dihydro-4-thioxo,2 1h-pyrimidinone, 4-mercapto-9ci
IUPAC Name 4-sulfanylidene-1,2,3,4-tetrahydropyrimidin-2-one
InChI Key OVONXEQGWXGFJD-UHFFFAOYSA-N
Molecular Formula C4H4N2OS
7

Sigma Aldrich 3-(Pyrrolidin-1-ylmethyl)aniline dihydrochloride

MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.

ENCOMPASS ENCOMPASS_PREFERRED
8

Cayman Chemical 4-ThIouracIl 500mg
SDP

A site-specific, photoactivatable probe used to detect RNA structures and nucleic acid-nucleic acid contacts

ENCOMPASS_PREFERRED
9

Sigma Aldrich Fine Chemicals Biosciences 4-Thiouridine >=98% | 13957-31-8 | MFCD00006538 | 250MG

4-Thiouridine >=98% | Purity: >=98% | Mol Wt: 260.27 | 13957-31-8 | MFCD00006538 | 250MG

ENCOMPASS
10

eMolecules​ Broadpharm / 2-Thiouridine / 100mg / 761707707 / BP-58834 / 98.000 / 20235-78-3 / MFCD03788697 / 260.260 / C9H12N2O5S

Broadpharm / 2-Thiouridine / 100mg / 761707707 / BP-58834 / 98.000 / 20235-78-3 / MFCD03788697 / 260.260 / C9H12N2O5S

ENCOMPASS_PREFERRED
11

Medchemexpress LLC 4-Thiouridine | 13957-31-8 | 99.98% | 260.27 | 25 MG
SDP

4-Thiouridine is a ribonucleoside analog, widely used in RNA analysis and (m)RNA labeling. It inhibits rRNA synthesis and causes a nucleolar stress response.

  • Functions as a ribonucleoside analog.
  • Utilized for RNA analysis and (m)RNA labeling.
  • Labels and purifies nascent rRNA at concentrations of 0-10 μM without significantly affecting rRNA synthesis.
  • Strongly inhibits the production and processing of rRNA at concentrations of ≥50 μM.
  • Targets nucleoside antimetabolite/analog.
  • Acts on the cell cycle/DNA damage pathway.

ENCOMPASS_PREFERRED
12

Cayman Chemical 4-ThIouracIl 1g
SDP

A site-specific, photoactivatable probe used to detect RNA structures and nucleic acid-nucleic acid contacts

ENCOMPASS_PREFERRED
13

Apexbio Technology LLC 2-Thiouracil 141-90-2 1g
SDP

2-Thiouracil (CAS 141-90-2) is a sulfur-containing derivative of uracil that functions as an inhibitor of thyroid hormone synthesis It exerts its antihyperthyroid effects by interfering with the enzymatic iodination of tyrosine residues within thyroglobulin thereby suppressing the production of triiodothyronine (T3) and thyroxine (T4) Due to its capacity to modulate thyroid function 2-Thiouracil is utilized in biomedical research to study thyroid hormone regulation and associated disorders as well as to model hypothyroid states in experimental settings

ENCOMPASS_PREFERRED
14

Apexbio Technology LLC 2-Thiouracil 141-90-2 5g
SDP

2-Thiouracil (CAS 141-90-2) is a sulfur-containing derivative of uracil that functions as an inhibitor of thyroid hormone synthesis It exerts its antihyperthyroid effects by interfering with the enzymatic iodination of tyrosine residues within thyroglobulin thereby suppressing the production of triiodothyronine (T3) and thyroxine (T4) Due to its capacity to modulate thyroid function 2-Thiouracil is utilized in biomedical research to study thyroid hormone regulation and associated disorders as well as to model hypothyroid states in experimental settings

ENCOMPASS_PREFERRED
15

Apexbio Technology LLC 2-Thiouracil 141-90-2 10mM (in 1mL DMSO)
SDP

2-Thiouracil (CAS 141-90-2) is a sulfur-containing derivative of uracil that functions as an inhibitor of thyroid hormone synthesis It exerts its antihyperthyroid effects by interfering with the enzymatic iodination of tyrosine residues within thyroglobulin thereby suppressing the production of triiodothyronine (T3) and thyroxine (T4) Due to its capacity to modulate thyroid function 2-Thiouracil is utilized in biomedical research to study thyroid hormone regulation and associated disorders as well as to model hypothyroid states in experimental settings

ENCOMPASS_PREFERRED