Trioxanes
Artemisinin, 98%
CAS: 63968-64-9 Molecular Formula: C15H22O5 Molecular Weight (g/mol): 282.336 MDL Number: MFCD00081057 InChI Key: BLUAFEHZUWYNDE-DKGJTOOQSA-N Synonym: artemisinine,artemisinin,gnf-pf-5341,artemisinin, 18,1s,4s,5r,8s,9r,12s,13r-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo 10.3.1.0^ 4,13 .0^ 8,13 hexadecan-10-one,1s,4s,5r,8s,9r,12s,13r-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo 10.3.1.04,13.08,13 hexadecan-10-one PubChem CID: 9838675 SMILES: CC1CCC2C(C(=O)OC3C24C1CCC(O3)(OO4)C)C
s-Trioxane, 99+%
CAS: 110-88-3 Molecular Formula: C3H6O3 Molecular Weight (g/mol): 90.08 MDL Number: MFCD00006563 InChI Key: BGJSXRVXTHVRSN-UHFFFAOYSA-N Synonym: s-trioxane,trioxymethylene,metaformaldehyde,triformol,formaldehyde, trimer,aldeform,formagene,marvosan,trioxan,sym-trioxane PubChem CID: 8081 ChEBI: CHEBI:38043 IUPAC Name: 1,3,5-trioxane SMILES: C1OCOCO1
1,3,5-Trioxane 99.0+%, TCI America™
CAS: 110-88-3 Molecular Formula: C3H6O3 Molecular Weight (g/mol): 90.078 MDL Number: MFCD00006563 InChI Key: BGJSXRVXTHVRSN-UHFFFAOYSA-N Synonym: s-trioxane,trioxymethylene,metaformaldehyde,triformol,formaldehyde, trimer,aldeform,formagene,marvosan,trioxan,sym-trioxane PubChem CID: 8081 ChEBI: CHEBI:38043 IUPAC Name: 1,3,5-trioxane SMILES: C1OCOCO1
Artemisinin 97.0+%, TCI America™
CAS: 63968-64-9 Molecular Formula: C15H22O5 Molecular Weight (g/mol): 282.336 MDL Number: MFCD00081057 InChI Key: BLUAFEHZUWYNDE-DKGJTOOQSA-N Synonym: artemisinine,artemisinin,gnf-pf-5341,artemisinin, 18,1s,4s,5r,8s,9r,12s,13r-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo 10.3.1.0^ 4,13 .0^ 8,13 hexadecan-10-one,1s,4s,5r,8s,9r,12s,13r-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo 10.3.1.04,13.08,13 hexadecan-10-one PubChem CID: 9838675 SMILES: CC1CCC2C(C(=O)OC3C24C1CCC(O3)(OO4)C)C
Dihydroartemisinin 98.0+%, TCI America™
CAS: 71939-50-9 Molecular Formula: C15H24O5 Molecular Weight (g/mol): 284.35 MDL Number: MFCD00236467,MFCD00274495,MFCD00274495,MFCD28384156 InChI Key: BJDCWCLMFKKGEE-KXTPALSWSA-N PubChem CID: 44264589 IUPAC Name: (4S,5R,8S,9R,10S,12R,13R)-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.0⁴,¹³.0⁸,¹³]hexadecan-10-ol SMILES: C[C@@H]1CC[C@H]2[C@@H](C)[C@@H](O)O[C@@H]3OC4(C)CC[C@@H]1[C@@]23OO4
Medchemexpress LLC Dihydroartemisinin (mixture of α and β isomers) | 131175-87-6 | MFCD00274495 | 98.0% | 284.35 g/mol | C15H24O5 | 100 MG
Dihydroartemisinin (mixture of α and β isomers) is an active metabolite of artemisinin used in research as an antimalarial and anticancer agent. It modulates cell death and autophagy pathways and is used in studies of parasite infection, apoptosis, and tumor biology.
- High purity: 98.0%.
- Molecular formula: C15H24O5; molecular weight: 284.35 g/mol.
- Available in research pack sizes including 100 MG.
- Active metabolite of artemisinin with antimalarial activity.
- Induces apoptosis and autophagy in cellular models.
- Powder storage: -20°C (3 years) or 4°C (2 years).
Selleck Chemical LLC Artemisinin S1282-50mg
Artemisinin is a sesquiterpene endoperoxide which is a potent antimalarial agent
Medchemexpress LLC Artemisinin (Standard) | 63968-64-9 | 98.6% | C₁₅H₂₂O₅ | 500 MG
Artemisinin (Standard) is the analytical standard for Artemisinin, a sesquiterpene lactone isolated from *Artemisia annua L.* plants. It functions as an anti-malarial agent and inhibits the AKT signaling pathway by decreasing pAKT. It has been shown to reduce cancer cell proliferation, migration, invasion, tumorigenesis, and metastasis, and also possesses neuroprotective effects.
- Analytical standard for research and analytical applications
- Functions as an anti-malarial agent
- Inhibits AKT signaling pathway by decreasing pAKT
- Reduces cancer cell proliferation, migration, invasion, tumorigenesis, and metastasis
- Possesses neuroprotective effects
- Used in qualitative, quantitative, and methodological research experiments such as HPLC, GC, and MS
Medchemexpress LLC Artemisinin | 63968-64-9 | 98.0% | C15H22O5 | 500 MG
Artemisinin, also known as Qinghaosu, is a sesquiterpene lactone and an anti-malarial agent derived from *Artemisia annua L.* plants. It inhibits the AKT signaling pathway, leading to a dose-dependent decrease in pAKT levels. Artemisinin reduces cancer cell proliferation, migration, invasion, tumorigenesis, and metastasis, and demonstrates neuroprotective effects.
- Anti-malarial agent
- Inhibits AKT signaling pathway
- Reduces cancer cell proliferation, migration, invasion, tumorigenesis, and metastasis
- Demonstrates neuroprotective capabilities
- Targets Plasmodium
- Exhibits antiproliferative activity against various human cancer cell lines
- Shows antiparasitic activity against *Toxoplasma gondii*
- Exhibits antiviral activity against Hepatitis B virus
Medchemexpress LLC Dihydroartemisinin | 71939-50-9 | 284.35 | 1 G
Dihydroartemisinin (DHA) is a potent antimalarial agent that modulates cellular processes. It up-regulates cytosolic RelA/p65 protein levels while down-regulating nuclear RelA/p65, effectively blocking its nuclear translocation. DHA also induces autophagy and suppresses NF-kB activation in RPMI 8226 cells. Furthermore, it can enhance the anti-tumor effect of photodynamic therapy (PDT) on esophageal cancer cells.
- Potent anti-malaria activity
- Modulates RelA/p65 protein levels
- Blocks nuclear translocation of RelA/p65
- Induces autophagy
- Suppresses NF-kB activation
- Enhances anti-tumor effects of photodynamic therapy
- Derived from Artemisia carvifolia Buch.-Ham. ex Roxb. plants
Medchemexpress LLC Artemisinin | 63968-64-9 | MFCD00081057 | 98.0% | 282.33 g/mol | C15H22O5 | 10 MG
Artemisinin analytical standard supplied as a 10 mg reference material for research and analytical applications. This sesquiterpene lactone is used for assay calibration, method development, and analytical validation, and it has documented antimalarial activity and reported effects in cell-based studies. Provided with molecular formula C15H22O5 and molecular weight 282.33 g/mol.
- Intended for assay calibration and method development.
- Suitable for analytical validation and quality control workflows.
- Supplied in a 10 mg vial for convenient handling.
- Sesquiterpene lactone with molecular formula C15H22O5 and molecular weight 282.33 g/mol.
Cayman Chemical 2-deoxy ArtemIsInIn 10mg
An inactive metabolite of artemisinin; is not active against the P. falciparum D-6 Sierra Leone clone (IC50 = 761.58 ng/ml)
Medchemexpress LLC Dihydroartemisinin (mixture of α and β isomers) | 71939-50-9 | MFCD00274495 | 98.0% | 284.35 g/mol | C15H24O5 | 500 MG
Dihydroartemisinin is an active metabolite of artemisinin used in research as an antimalarial and as a probe for antiproliferative and autophagy-related pathways. It is provided as a high-purity compound and is available in multiple solid and solution formats for in vitro studies.
- High purity (98.0%) suitable for research applications.
- Available as solids and as 10 mM solutions in DMSO for immediate use.
- Relevant for studies of parasite biology, apoptosis, and autophagy.
- Well-characterized with CAS number 71939-50-9 and published spectral data.
- Supplied in small pack sizes convenient for bench-top experiments.
Apexbio Technology LLC Dihydroartemisinin 71939-50-9 10mM (in 1mL DMSO)
Dihydroartemisinin (CAS 71939-50-9) is a bioactive compound whose antimalarial action primarily involves interaction with intracellular iron followed by generation of reactive oxygen species leading to damage of Plasmodium parasite biomolecules and subsequent parasite death In in vitro studies dihydroartemisinin demonstrates potent antiplasmodial activity with an IC50 value of approximately 3 10 nM in Plasmodium falciparum strains Based on these pharmacological properties dihydroartemisinin holds research potential in antimalarial anti-inflammatory and antipsoriasis applications