Aralkylamines
Betahistine Hydrochloride, USP, 99-101%, Spectrum™ Chemical
CAS: 5579-84-0 Molecular Formula: C8H14Cl2N2 Molecular Weight (g/mol): 209.11 InChI Key: XVDFMHARQUBJRE-UHFFFAOYSA-N IUPAC Name: dihydrogen methyl[2-(pyridin-2-yl)ethyl]amine dichloride SMILES: [H+].[H+].[Cl-].[Cl-].CNCCC1=CC=CC=N1
(S)-(-)-N-Methyl-1-phenylethylamine 98.0+%, TCI America™
CAS: 19131-99-8 Molecular Formula: C9H13N Molecular Weight (g/mol): 135.21 MDL Number: MFCD00067113 InChI Key: RCSSHZGQHHEHPZ-QMMMGPOBSA-N Synonym: s---n-methyl-1-phenylethylamine,s-n-methyl-1-phenylethanamine,unii-4mu17yen7y,4mu17yen7y,methyl 1s-1-phenylethyl amine,n-methyl-1-phenylethylamine, s,s---n,alpha-dimethylbenzylamine,n-methyl-n-1s-1-phenylethyl amine,pubchem18717 PubChem CID: 2060073 IUPAC Name: (1S)-N-methyl-1-phenylethanamine SMILES: CC(C1=CC=CC=C1)NC
DL-alpha-Methylbenzylamine, 99%
CAS: 618-36-0 MDL Number: MFCD00008069 InChI Key: RQEUFEKYXDPUSK-UHFFFAOYSA-N Synonym: 1-phenylethylamine,alpha-methylbenzylamine,alpha-phenylethylamine,dl-alpha-methylbenzylamine,1-phenethylamine,alpha-aminoethylbenzene,1-amino-1-phenylethane,1-phenylethan-1-amine,a-methylbenzylamine,alpha-methylbenzenemethanamine PubChem CID: 7408 ChEBI: CHEBI:670 IUPAC Name: 1-phenylethanamine SMILES: CC(C1=CC=CC=C1)N
Medchemexpress LLC Clinafloxacin hydrochloride | 105956-99-8 | MFCD03840545 | 10 MG
Clinafloxacin hydrochloride is the hydrochloride salt of clinafloxacin, a potent broad-spectrum fluoroquinolone antibiotic used for research. It exhibits activity against Gram-positive and Gram-negative bacteria and is supplied as a research reagent for antibacterial studies and assay development.
- Hydrochloride salt form for improved solubility.
- Broad-spectrum fluoroquinolone antibacterial activity.
- Suitable for in vitro antibacterial research and assay development.
- Molecular weight 402.25 g/mol; CAS 105956-99-8.
- Available in small research pack sizes, e.g. 10 mg.
Medchemexpress LLC Clinafloxacin (hydrochloride) | 105956-99-8 | 99.6% | 25 MG
Clinafloxacin hydrochloride is a potent and broad-spectrum fluoroquinolone antibiotic. It exhibits inhibitory activity against gram-positive, gram-negative bacteria, and anaerobic pathogens in vitro, acting against DNA gyrase and topoisomerase IV of *S. aureus*.
- Potent and broad-spectrum fluoroquinolone antibiotic
- Inhibits gram-positive, gram-negative bacteria, and anaerobic pathogens
- Active against DNA gyrase and topoisomerase IV of *S. aureus*
- Effective against penicillin-resistant, ciprofloxacin-susceptible pneumococcal meningitis
- Exhibits activity against *S. pneumonia*
Medchemexpress LLC Clinafloxacin hydrochloride | 105956-99-8 | 99.6% | 50 MG
Clinafloxacin hydrochloride is a potent, broad-spectrum fluoroquinolone antibiotic. It demonstrates inhibitory activity against gram-positive and gram-negative bacteria, as well as anaerobic pathogens in vitro. This compound targets DNA gyrase and topoisomerase IV of *S. aureus*.
- Effective against *S. pneumonia* with an MIC of 1 μg/ml for parC-gyrA mutants.
- Shows antibacterial activities against target-altered mutant strains of *S. aureus*.
- Effective in treating penicillin-resistant, ciprofloxacin-susceptible pneumococcal meningitis in a rabbit model in vivo.
- Appears as a light yellow to yellow solid.
- For research use only.
Medchemexpress LLC Clinafloxacin (hydrochloride) | 105956-99-8 | 99.6% | 5 MG
Clinafloxacin hydrochloride (AM 1091 hydrochloride) is a potent, broad-spectrum fluoroquinolone antibiotic with inhibitory activity against gram-positive, gram-negative bacteria, and anaerobic pathogens. It targets DNA gyrase and topoisomerase IV, making it suitable for laboratory research.
- Potent and broad-spectrum fluoroquinolone antibiotic
- Active against gram-positive, gram-negative, and anaerobic pathogens
- Targets DNA gyrase and topoisomerase IV
- For research use only
- Soluble in DMSO
Medchemexpress LLC Navlimetostat hydrochloride | 2630904-45-7 | MFCD34604075 | 99.61% | 501.34 | 50 MG
Navlimetostat hydrochloride, also known as MRTX-1719 hydrochloride, is a potent, orally active, selective PRMT5-MTA complex inhibitor (IC50 values of 3.6 nM for PRMT5-MTA and 20.5 nM for PRMT5). It binds strongly to the PRMT5-MTA complex (KD of 0.14 pM) and demonstrates antineoplastic activity in vitro and in vivo, making it suitable for cancer research.
- In vitro activity: Inhibits PRMT5 activity (IC50 8 nM) and viability (IC50 12 nM) in MTAP-deleted HCT116 cells.
- In vivo activity: Significantly reduces tumor growth in Lu-99 orthotopic xenograft models (12.5-100 mg/kg/day, oral, 21 days).
- Pharmacokinetics: High bioavailability in CD-1 mice (80% at 30 mg/kg p.o.) and Beagle dogs (59% at 10 mg/kg p.o.).