Carboximidamides
Medchemexpress LLC AN0128, a boron-containing antibacterial and anti-inflammatory agent | 872044-70-7 | 99.0% | 400.06 | 100 MG
AN0128, a boron-containing antibacterial and anti-inflammatory agent | 872044-70-7 | 99.0% | 400.06 | 100 MG
Medchemexpress LLC ((bis(3-chloro-4-methylphenyl)boraneyl)oxy)(3-hydroxypyridin-2-yl)methanone | 872044-70-7 | MFCD18251581 | 99.0% | 400.06 g/mol | C20H16BCl2NO3 | 5 MG
AN0128 is a boron-containing antibacterial and anti-inflammatory research compound with demonstrated in vitro activity against several Gram-positive bacteria. It is intended for use in preclinical research on periodontal and cutaneous diseases and is supplied as a solid with high purity; handle protected from light.
Medchemexpress LLC AN0128 | 872044-70-7 | 98.95% | 400.06 | 50 MG
AN0128 is a boron-containing antibacterial and anti-inflammatory agent. It is effective against various bacteria including *S. aureus*, *S. epidermidis*, *P. acnes*, and *B. subtilis*. This compound can be utilized in the research of periodontal disease and cutaneous diseases, demonstrating strong inhibition of pro-inflammatory cytokines *in vitro* and reduction of inflammatory infiltrate and bone loss *in vivo*.
- Boron-containing antibacterial and anti-inflammatory agent
- Effective against *S. aureus*, *S. epidermidis*, *P. acnes*, and *B. subtilis*
- Utilized for research on periodontal disease and cutaneous diseases
- Inhibits release of pro-inflammatory cytokines (TNF-α, IL-1β) in PBMCs
- Reduces inflammatory infiltrate and bone loss *in vivo*
- Increases bone area and bone volume in experimental periodontitis rat model
- Decreases bone loss and inflammation in experimental periodontitis rat model
Medchemexpress LLC AN0128 | 872044-70-7 | 98.95% | 400.06 | 10 MG
AN0128 is a boron-containing antibacterial and anti-inflammatory agent. It has demonstrated efficacy against *S. aureus*, *S. epidermidis*, *P. acnes*, and *B. subtilis* with minimum inhibitory concentration (MIC) values of 1, 0.5, 0.3, and 1 μg/mL, respectively. This product is intended for research in periodontal and cutaneous diseases.
- Acts as an antibacterial agent.
- Functions as an anti-inflammatory agent.
- Inhibits the release of pro-inflammatory cytokines (TNF-α, IL-1β) in human peripheral blood mononuclear cells (PBMCs) at 10 μM.
- Reduces inflammatory infiltrate and bone loss in experimental periodontitis.
- Shows greater effectiveness than a common toothpaste in reducing bone loss and increasing bone volume in animal models of periodontitis.
- Available in solid form, white to off-white in color.